PMID- 24618220
OWN - NLM
STAT- MEDLINE
DCOM- 20141222
LR  - 20140430
IS  - 1532-2688 (Electronic)
IS  - 1059-1311 (Linking)
VI  - 23
IP  - 5
DP  - 2014 May
TI  - Subacute encephalopathy with seizures in alcoholics (SESA syndrome) revisited.
PG  - 393-6
LID - S1059-1311(14)00040-5 [pii]
LID - 10.1016/j.seizure.2014.02.002 [doi]
AB  - PURPOSE: The aim of this paper is to describe two additional cases of subacute 
      encephalopathy with seizures in alcoholics (SESA syndrome), and to propose that 
      this entity now should be considered as a subtype of nonconvulsive status 
      epilepticus (NCSE). METHODS: We retrospectively analyzed the clinical 
      characteristics, electroencephalography (EEG), neuroimaging data, and prognosis 
      of these two further cases of SESA syndrome. In addition, we compare our findings 
      with the cases previously described in the English literature in order to propose 
      new diagnostic criteria. RESULTS: Two adults with history of chronic alcohol 
      abuse were admitted because of confusion and seizures. A routine EEG showed 
      frequent periodic lateralized epileptiform discharges (PLEDs) localized over the 
      right temporal regions. In one case, we captured two complex partial seizures 
      (CPSs) arising from the right hemisphere. Neuroimaging studies revealed subjacent 
      chronic vascular pathology. Following transfer to the intensive care unit (ICU), 
      both improved to antiepileptic treatment and were discharged with full recovery. 
      CONCLUSION: On the basis of our findings and a review of the literature, we 
      suggest that SESA syndrome represents a subtype of partial or 
      localization-related NCSE given its particular clinical, electroencephalographic, 
      neuroimaging and prognostic characteristics.
CI  - Copyright (c) 2014 British Epilepsy Association. Published by Elsevier Ltd. All 
      rights reserved.
FAU - Fernandez-Torre, Jose L
AU  - Fernandez-Torre JL
AD  - Department of Clinical Neurophysiology, Marques de Valdecilla University 
      Hospital, Santander, Cantabria, Spain; Department of Physiology and Pharmacology, 
      University of Cantabria (UNICAN), Santander, Cantabria, Spain; Instituto de 
      Formacion e Investigacion Marques de Valdecilla (IFIMAV), Santander, Spain. 
      Electronic address: jlfernandez@humv.es.
FAU - Kaplan, Peter W
AU  - Kaplan PW
AD  - Department of Neurology, Johns Hopkins University School of Medicine, Johns 
      Hopkins Bayview Medical Center, Baltimore, USA.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Review
DEP - 20140215
PL  - England
TA  - Seizure
JT  - Seizure
JID - 9306979
RN  - 0 (Anticonvulsants)
SB  - IM
MH  - Alcoholics/psychology
MH  - Anticonvulsants/*therapeutic use
MH  - Brain Damage, Chronic/diagnosis/*drug therapy/etiology
MH  - *Electroencephalography
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Seizures/diagnosis/*drug therapy/etiology
MH  - Status Epilepticus/*drug therapy/etiology
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Alcoholics
OT  - Complex partial status epilepticus
OT  - Nonconvulsive status epilepticus
OT  - Periodic lateralized epileptiform discharges
OT  - SESA syndrome
EDAT- 2014/03/13 06:00
MHDA- 2014/12/23 06:00
CRDT- 2014/03/13 06:00
PHST- 2013/10/05 00:00 [received]
PHST- 2014/02/07 00:00 [revised]
PHST- 2014/02/09 00:00 [accepted]
PHST- 2014/03/13 06:00 [entrez]
PHST- 2014/03/13 06:00 [pubmed]
PHST- 2014/12/23 06:00 [medline]
AID - S1059-1311(14)00040-5 [pii]
AID - 10.1016/j.seizure.2014.02.002 [doi]
PST - ppublish
SO  - Seizure. 2014 May;23(5):393-6. doi: 10.1016/j.seizure.2014.02.002. Epub 2014 Feb 
      15.