PMID- 24624795
OWN - NLM
STAT- MEDLINE
DCOM- 20140408
LR  - 20140314
IS  - 0042-465X (Print)
IS  - 0042-465X (Linking)
VI  - 129
IP  - 6
DP  - 2013 Nov-Dec
TI  - [Depth of retinal vessels and electroretinogram changes in stage 3 and 4 
      cicatricial retinopathy of prematurity].
PG  - 10-4
AB  - The article presents the results of a study on retinal vessels in stage 3 and 4 
      cicatricial retinopathy of prematurity (ROP) by means of spectral-domain optical 
      coherence tomography (SD OCT). The study comprised 29 children (40 eyes) aged 
      from 6 month to 12 years with stage 3 and 4 cicatricial ROP, of which 17 children 
      (21 eyes) under 6 and 12 children (19 eyes) over 6 years of age. SD OCT was used 
      to approach the depth of retinal vessels and the caliber of the first-order 
      vessels. Only in 8 eyes (20%) proper retinal vessels were located in the ganglion 
      cell layer. In 12 eyes (30%) the vessels occurred in the nerve fiber layer and in 
      other 20 eyes (50%) they appeared to have extraretinal growth. Thus, 
      physiological depth of retinal vessels (i.e. in the ganglion cell layer) was seen 
      in only 20% of cases. A relationship between the degree of retinal vascular 
      system displacement and the presence of extraretinal tissue was established (p < 
      0.01). No correlation was found between gestational age and birth weight and the 
      location of retinal vessels (p > 0.05). Location of retinal vessels can serve as 
      a severity criterion, an important test to reveal preclinical negative changes, 
      and a risk factor for late complications (tractional retinoschisis, detachment 
      and tears). A tendency to smaller diameter of retinal vessels and higher 
      artheriovenous index in children with ROP in comparison with healthy full-term 
      children of the same age might indicate a decrease of retinal blood filling which 
      might later cause development of retinal dystrophies.
FAU - Katargina, L A
AU  - Katargina LA
FAU - Riabtsev, D I
AU  - Riabtsev DI
FAU - Kogoleva, L V
AU  - Kogoleva LV
LA  - rus
PT  - Comparative Study
PT  - English Abstract
PT  - Journal Article
PL  - Russia (Federation)
TA  - Vestn Oftalmol
JT  - Vestnik oftalmologii
JID - 0415216
SB  - IM
MH  - Child
MH  - Child, Preschool
MH  - Electroretinography/*methods
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Infant
MH  - Male
MH  - Prognosis
MH  - Retina/pathology/*physiopathology
MH  - Retinal Vessels/*pathology
MH  - Retinopathy of Prematurity/*diagnosis/physiopathology
MH  - Severity of Illness Index
MH  - Tomography, Optical Coherence/methods
EDAT- 2014/03/15 06:00
MHDA- 2014/04/09 06:00
CRDT- 2014/03/15 06:00
PHST- 2014/03/15 06:00 [entrez]
PHST- 2014/03/15 06:00 [pubmed]
PHST- 2014/04/09 06:00 [medline]
PST - ppublish
SO  - Vestn Oftalmol. 2013 Nov-Dec;129(6):10-4.