PMID- 24625040 OWN - NLM STAT- MEDLINE DCOM- 20141217 LR - 20220409 IS - 1744-8379 (Electronic) IS - 1473-7167 (Linking) VI - 14 IP - 2 DP - 2014 Apr TI - The minimum clinically important difference for EQ-5D index: a critical review. PG - 221-33 LID - 10.1586/14737167.2014.894462 [doi] AB - The European Quality of Life-5 Dimensions Questionnaire (EQ-5D) is the most common instrument to value health outcomes under the patient's perspective. Several studies have investigated whether observed changes are meaningful to patients, using a variety of approaches to estimate the minimum clinically important difference (MCID). This study provides an overview of the state of art of the estimation of the MCID for the three-level EQ-5D index based on the UK scoring algorithm, critically assessing the available evidence. The interest in estimation of MCID for the EQ-5D has been increasing in recent years. However, some additional standardization in the estimation procedures may be of value, in order to enhance the ability to make comparisons across measures and disease areas. Further methodological research might also contribute to reducing gaps between theory and practice. FAU - Coretti, Silvia AU - Coretti S AD - Dr. Catholic University of Sacred Hearth - Faculty of Economics, L.go F. Vito 1, Rome 00168, Italy. FAU - Ruggeri, Matteo AU - Ruggeri M FAU - McNamee, Paul AU - McNamee P LA - eng GR - HERU1/CSO_/Chief Scientist Office/United Kingdom PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Review PL - England TA - Expert Rev Pharmacoecon Outcomes Res JT - Expert review of pharmacoeconomics & outcomes research JID - 101132257 SB - IM MH - Europe MH - Humans MH - *Quality of Life MH - *Surveys and Questionnaires EDAT- 2014/03/15 06:00 MHDA- 2014/12/18 06:00 CRDT- 2014/03/15 06:00 PHST- 2014/03/15 06:00 [entrez] PHST- 2014/03/15 06:00 [pubmed] PHST- 2014/12/18 06:00 [medline] AID - 10.1586/14737167.2014.894462 [doi] PST - ppublish SO - Expert Rev Pharmacoecon Outcomes Res. 2014 Apr;14(2):221-33. doi: 10.1586/14737167.2014.894462.