PMID- 24629695 OWN - NLM STAT- MEDLINE DCOM- 20151201 LR - 20191210 IS - 1578-8989 (Electronic) IS - 0025-7753 (Linking) VI - 144 IP - 6 DP - 2015 Mar 15 TI - [Diagnostic performance of surface electrocardiogram in early detection of chagasic cardiomyopathy]. PG - 254-6 LID - S0025-7753(14)00122-5 [pii] LID - 10.1016/j.medcli.2014.01.028 [doi] AB - BARCKGROUND AND OBJECTIVE: Contrast-enhanced cardiac magnetic resonance imaging (CMR) allows early detection of myocardial involvement by Trypanosoma cruzi infection. The aim of our study was to assess the diagnostic performance of the surface electrocardiogram (ECG) in the early detection of Chagas' cardiomyopathy (CCM) compared with CMR. METHODS: We included 43 asymptomatic patients (30 women, 42 +/- 9.8 years), diagnosed of Chagas disease. The sample was divided into 2 groups according to the presence (n=17) or absence (n=26) of electrocardiographic abnormalities. All patients underwent CMR and late gadolinium enhancement (LGE) was used as a marker of early myocardial involvement. RESULTS: Six (14%) patients had a LGE significantly higher in the group who had electrocardiographic abnormalities (29 vs. 4%, P<.05). With CMR as the method of reference, the ECG had a sensitivity of 83% and a negative predictive value of 96% to detect CCM. CONCLUSION: ECG is a useful, inexpensive and globally available tool for the screening of CCM in asymptomatic patients but with proven myocardial involvement in CMR. CI - Copyright (c) 2013 Elsevier Espana, S.L.U. All rights reserved. FAU - Bochard-Villanueva, Bruno AU - Bochard-Villanueva B AD - Servicio de Cardiologia, Consorcio Hospital General Universitario de Valencia, Valencia, Espana. Electronic address: bbochard@gmail.com. FAU - Estornell-Erill, Jordi AU - Estornell-Erill J AD - Unidad de Imagen Cardiaca, ERESA, Consorcio Hospital General Universitario de Valencia, Valencia, Espana. FAU - Fabregat-Andres, Oscar AU - Fabregat-Andres O AD - Servicio de Cardiologia, Consorcio Hospital General Universitario de Valencia, Valencia, Espana; Servicios Medicos Villarreal Club de Futbol SAD, Villarreal, Castellon, Espana. FAU - Garcia-Gonzalez, Pilar AU - Garcia-Gonzalez P AD - Servicio de Cardiologia, Consorcio Hospital General Universitario de Valencia, Valencia, Espana. FAU - Morell-Cabedo, Salvador AU - Morell-Cabedo S AD - Servicio de Cardiologia, Consorcio Hospital General Universitario de Valencia, Valencia, Espana. FAU - Ridocci-Soriano, Francisco AU - Ridocci-Soriano F AD - Servicio de Cardiologia, Consorcio Hospital General Universitario de Valencia, Valencia, Espana; Departamento de Medicina, Facultad de Medicina, Universitat de Valencia, Valencia, Espana. LA - spa PT - Comparative Study PT - Evaluation Study PT - Journal Article TT - Rendimiento diagnostico del electrocardiograma de superficie en la deteccion precoz de miocardiopatia chagasica. DEP - 20140313 PL - Spain TA - Med Clin (Barc) JT - Medicina clinica JID - 0376377 SB - IM MH - Adult MH - Asymptomatic Infections MH - Chagas Cardiomyopathy/*diagnosis MH - Early Diagnosis MH - *Electrocardiography MH - Female MH - Humans MH - *Magnetic Resonance Imaging MH - Male MH - Middle Aged MH - Retrospective Studies MH - Sensitivity and Specificity OTO - NOTNLM OT - Chagas cardiomyopathy OT - Chagas disease OT - Diagnostico precoz OT - Early diagnosis OT - Electrocardiografia OT - Electrocardiography OT - Enfermedad de Chagas OT - Magnetic resonance imaging OT - Miocardiopatia chagasica OT - Resonancia magnetica EDAT- 2014/03/19 06:00 MHDA- 2015/12/15 06:00 CRDT- 2014/03/18 06:00 PHST- 2013/11/15 00:00 [received] PHST- 2014/01/21 00:00 [revised] PHST- 2014/01/23 00:00 [accepted] PHST- 2014/03/18 06:00 [entrez] PHST- 2014/03/19 06:00 [pubmed] PHST- 2015/12/15 06:00 [medline] AID - S0025-7753(14)00122-5 [pii] AID - 10.1016/j.medcli.2014.01.028 [doi] PST - ppublish SO - Med Clin (Barc). 2015 Mar 15;144(6):254-6. doi: 10.1016/j.medcli.2014.01.028. Epub 2014 Mar 13.