PMID- 24640937 OWN - NLM STAT- MEDLINE DCOM- 20150602 LR - 20181202 IS - 1473-4877 (Electronic) IS - 0300-7995 (Linking) VI - 30 IP - 6 DP - 2014 Jun TI - The relationship between vitamin D and obesity. PG - 1197-9 LID - 10.1185/03007995.2014.900004 [doi] AB - Currently, vitamin D deficiency and obesity are pandemic diseases and they are associated with cardiovascular (CV) disease, metabolic syndrome and type 2 diabetes mellitus (T2DM) and other diseases. Concentrations of 25-hydroxyvitamin D (25(OH)D) (25D) are considered as the best indicator of total body vitamin D stores. An association between reduced circulating 25D concentrations and obesity is well known, but the mechanisms are not totally clear. The role of vitamin D supplementation is still uncertain and prospective interventions will establish its influence, if any, in the treatment of obesity. Vitamin D deficiency is associated with the presence of a cardiometabolic risk profile in the obese. Future trials may establish a role for Vitamin D supplementation in individuals at increased CV risk. FAU - Soskic, Sanja AU - Soskic S AD - Institute of nuclear sciences 'Vinca', Laboratory for Radiobiology and Molecular Genetics, University of Belgrade , Belgrade , Serbia. FAU - Stokic, Edita AU - Stokic E FAU - Isenovic, Esma R AU - Isenovic ER LA - eng PT - Editorial PT - Research Support, Non-U.S. Gov't DEP - 20140318 PL - England TA - Curr Med Res Opin JT - Current medical research and opinion JID - 0351014 RN - 1406-16-2 (Vitamin D) RN - A288AR3C9H (25-hydroxyvitamin D) SB - IM MH - Cardiovascular Diseases/blood MH - Diabetes Mellitus, Type 2/blood MH - Humans MH - Metabolic Syndrome/blood MH - Obesity/*blood MH - Vitamin D/*analogs & derivatives/blood MH - Vitamin D Deficiency/*blood OTO - NOTNLM OT - Cardiovascular disease OT - Metabolic syndrome OT - Obesity OT - Type 2 diabetes OT - Vitamin D EDAT- 2014/03/20 06:00 MHDA- 2015/06/03 06:00 CRDT- 2014/03/20 06:00 PHST- 2014/03/20 06:00 [entrez] PHST- 2014/03/20 06:00 [pubmed] PHST- 2015/06/03 06:00 [medline] AID - 10.1185/03007995.2014.900004 [doi] PST - ppublish SO - Curr Med Res Opin. 2014 Jun;30(6):1197-9. doi: 10.1185/03007995.2014.900004. Epub 2014 Mar 18.