PMID- 24655652
OWN - NLM
STAT- MEDLINE
DCOM- 20150413
LR  - 20140324
IS  - 1527-5418 (Electronic)
IS  - 0890-8567 (Linking)
VI  - 53
IP  - 4
DP  - 2014 Apr
TI  - Childhood attention-deficit/hyperactivity disorder symptoms are risk factors for 
      obesity and physical inactivity in adolescence.
PG  - 425-36
LID - S0890-8567(14)00077-X [pii]
LID - 10.1016/j.jaac.2014.01.009 [doi]
AB  - OBJECTIVE: To prospectively investigate the association and directionality 
      between attention-deficit/hyperactivity disorder (ADHD) symptoms and obesity from 
      childhood to adolescence in the general population. We examined whether 
      obesogenic behaviors, namely, physical inactivity and binge eating, underlie the 
      potential ADHD symptom-obesity association. We explored whether childhood conduct 
      disorder (CD) symptoms are related to adolescent obesity/physical inactivity. 
      METHOD: At 7 to 8 years (n = 8,106), teachers reported ADHD and CD symptoms, and 
      parents reported body mass index (BMI) and physically active play. At 16 years 
      (n = 6,934), parents reported ADHD symptoms; adolescents reported physical 
      activity (transformed to metabolic equivalent of task [MET] hours per week) and 
      binge eating; BMI and waist-hip ratio (WHR) were measured via clinical 
      examination. Obesity was defined using the International Obesity Task Force 
      (IOTF) cut-offs for BMI and the 95th percentile cut-off for WHR. RESULTS: 
      Childhood ADHD symptoms significantly predicted adolescent obesity, rather than 
      the opposite. Inattention-hyperactivity symptoms at 8 years were associated with 
      indices of obesity at 16 years (obese BMI: odds ratio [OR] = 1.91, 95% confidence 
      interval [CI] = 1.10-3.33; 95th percentile WHR: OR = 1.71, 95% CI = 1.05-2.78), 
      adjusted for gender, baseline BMI, physical activity, family structure change, 
      and maternal education. Child CD symptoms associated with indices of adolescent 
      obesity. Reduced physically active play in childhood predicted adolescent 
      inattention (OR = 1.61, 95% CI = 1.16-2.24). Childhood ADHD and CD symptoms were 
      linked with physical inactivity in adolescence (inattention-hyperactivity; 
      OR = 1.60, 95% CI = 1.20-2.13), but not binge eating. Physical inactivity 
      mediated the associations. CONCLUSIONS: Children with ADHD or CD symptoms are at 
      increased risk for becoming obese and physically inactive adolescents. Physical 
      activity may be beneficial for both behavior problems and obesity.
CI  - Copyright (c) 2014 American Academy of Child and Adolescent Psychiatry. Published 
      by Elsevier Inc. All rights reserved.
FAU - Khalife, Natasha
AU  - Khalife N
AD  - Imperial College London, UK.
FAU - Kantomaa, Marko
AU  - Kantomaa M
AD  - Imperial College London, UK; LIKES - Research Center for Sports and Health 
      Sciences, Finland.
FAU - Glover, Vivette
AU  - Glover V
AD  - Imperial College London, UK.
FAU - Tammelin, Tuija
AU  - Tammelin T
AD  - LIKES - Research Center for Sports and Health Sciences, Finland.
FAU - Laitinen, Jaana
AU  - Laitinen J
AD  - Finnish Institute for Occupational Health, Finland.
FAU - Ebeling, Hanna
AU  - Ebeling H
AD  - Clinic of Child Psychiatry, University and University Hospital of Oulu, Finland.
FAU - Hurtig, Tuula
AU  - Hurtig T
AD  - Institute of Health Sciences, University of Oulu, Finland.
FAU - Jarvelin, Marjo-Riitta
AU  - Jarvelin MR
AD  - Imperial College London, UK; Medical Research Council (MRC) Health Protection 
      Agency (HMA) Centre for Environment and Health, Imperial College, UK; Institute 
      of Health Sciences, University of Oulu, Finland; Biocenter Oulu, University of 
      Oulu, Finland; Unit of Primary Care, Oulu University Hospital, Finland; and the 
      National Institute for Health and Welfare, Finland.
FAU - Rodriguez, Alina
AU  - Rodriguez A
AD  - Imperial College London, UK; Mid Sweden University, Sweden. Electronic address: 
      a.rodriguez@imperial.ac.uk.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140203
PL  - United States
TA  - J Am Acad Child Adolesc Psychiatry
JT  - Journal of the American Academy of Child and Adolescent Psychiatry
JID - 8704565
SB  - IM
MH  - Adolescent
MH  - Attention Deficit Disorder with Hyperactivity/*epidemiology
MH  - Bulimia/epidemiology
MH  - Child
MH  - Comorbidity
MH  - Conduct Disorder/*epidemiology
MH  - Female
MH  - Finland/epidemiology
MH  - Humans
MH  - Male
MH  - Motor Activity/physiology
MH  - Pediatric Obesity/*epidemiology
MH  - Risk Factors
OTO - NOTNLM
OT  - attention-deficit/hyperactivity disorder symptoms
OT  - conduct disorder symptoms
OT  - disruptive behavior
OT  - obesity
OT  - physical inactivity
EDAT- 2014/03/25 06:00
MHDA- 2015/04/14 06:00
CRDT- 2014/03/25 06:00
PHST- 2013/07/08 00:00 [received]
PHST- 2014/01/22 00:00 [revised]
PHST- 2014/01/27 00:00 [accepted]
PHST- 2014/03/25 06:00 [entrez]
PHST- 2014/03/25 06:00 [pubmed]
PHST- 2015/04/14 06:00 [medline]
AID - S0890-8567(14)00077-X [pii]
AID - 10.1016/j.jaac.2014.01.009 [doi]
PST - ppublish
SO  - J Am Acad Child Adolesc Psychiatry. 2014 Apr;53(4):425-36. doi: 
      10.1016/j.jaac.2014.01.009. Epub 2014 Feb 3.