PMID- 24656647
OWN - NLM
STAT- MEDLINE
DCOM- 20141222
LR  - 20160414
IS  - 1773-0619 (Electronic)
IS  - 0028-3770 (Linking)
VI  - 60
IP  - 1-2
DP  - 2014 Feb-Apr
TI  - [Nasal dermal sinus in children: a review based on a series of 6 cases].
PG  - 27-32
LID - S0028-3770(14)00008-3 [pii]
LID - 10.1016/j.neuchi.2013.10.123 [doi]
AB  - INTRODUCTION: Nasal dermal sinus in children (NDSC) is a rare malformation 
      (1/20,000 to 1/40,000). Apart from local infection, they present as median nasal 
      lump or pit on the dorsum and their diagnosis and treatment are often delayed. 
      Consequences of untreated NDSC are: local infection, meningitis, and empyema, due 
      to their frequent intracranial extension. PATIENTS AND METHODS: Six cases of NDSC 
      were retrospectively reviewed (5 boys and one girl), all treated between 2006 and 
      2012 in our institution (Nancy University Hospital). All patients underwent a 
      brain and facial CT-scan and MR imaging to check any bony lesions, skull base 
      extension by foramen caecum, course of the sinus and the possible associated brain 
      malformations. Evolution, treatment and follow-up (FU) were conducted by the same 
      multidisciplinary team (neurosurgeon, ENT surgeon, and plastic surgeon). Children 
      were operated on by a conjoined approach (cranial and facial) for removal of the 
      sinus and its intracranial extension. RESULTS: Mean age at diagnosis was 12 
      months (birth-36 months). Initial presentation consisted of three local 
      infections, one dorsum nasal lump, one CSF leakage, and one asymptomatic child. 
      Five children presented with a skull base extension. There were no associated 
      brain malformations. We observed only one surgical complication (bleeding from 
      the anterior part of the superior sagittal sinus during dissection) leading to 
      blood transfusion. Pathology results confirmed three dermoid cysts, one 
      epidermoid cyst, one cyst with granulation tissue, and negative in one case. 
      Average FU was 30.8 months (4-84 months). Two recurrences (same child) occurred, 
      leading to two re-operations. There were no recurrences or complications at the 
      end of FU. CONCLUSION: NDSC are rare malformations, mostly diagnosed before the 
      age of three years, due to an infectious complication. The aim of the treatment 
      is complete removal to avoid recurrence, and a multidisciplinary strategy is 
      required.
CI  - Copyright (c) 2014. Published by Elsevier Masson SAS.
FAU - Klein, O
AU  - Klein O
AD  - Service de neurochirurgie pediatrique, hopital d'Enfants, CHU de Nancy, 
      universite de Lorraine, 4, rue du Morvan, 54500 Vandoeuvre-Les-Nancy, France. 
      Electronic address: oliklein@yahoo.com.
FAU - Simon, E
AU  - Simon E
AD  - Service de chirurgie maxillo-faciale et plastique, CHU de Nancy, universite de 
      Lorraine, 54500 Nancy, France.
FAU - Coffinet, L
AU  - Coffinet L
AD  - Service d'ORL, CHU de Nancy, universite de Lorraine, 54500 Nancy, France.
FAU - Joud, A
AU  - Joud A
AD  - Service de neurochirurgie pediatrique, hopital d'Enfants, CHU de Nancy, 
      universite de Lorraine, 4, rue du Morvan, 54500 Vandoeuvre-Les-Nancy, France.
FAU - Ghetemme, C
AU  - Ghetemme C
AD  - Service de neurochirurgie pediatrique, hopital d'Enfants, CHU de Nancy, 
      universite de Lorraine, 4, rue du Morvan, 54500 Vandoeuvre-Les-Nancy, France.
FAU - Marchal, J-C
AU  - Marchal JC
AD  - Service de neurochirurgie pediatrique, hopital d'Enfants, CHU de Nancy, 
      universite de Lorraine, 4, rue du Morvan, 54500 Vandoeuvre-Les-Nancy, France.
LA  - fre
PT  - Case Reports
PT  - English Abstract
PT  - Journal Article
TT  - Fistules du dorsum nasal de l'enfant: mise au point a propos d'une serie de 6 
      cas.
DEP - 20140320
PL  - France
TA  - Neurochirurgie
JT  - Neuro-Chirurgie
JID - 0401057
SB  - IM
MH  - Dermoid Cyst/*surgery
MH  - Female
MH  - Humans
MH  - Male
MH  - Neoplasm Recurrence, Local/diagnosis/*surgery
MH  - Nose Neoplasms/diagnosis/*surgery
MH  - Retrospective Studies
MH  - Spina Bifida Occulta/diagnosis/*surgery
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Craniofacial
OT  - Embryologie
OT  - Embryology
OT  - Fistule du dorsum nasal
OT  - Kyste dermoide nasal
OT  - Nasal dermal sinus
OT  - Nasal dermoid sinus cyst
EDAT- 2014/03/25 06:00
MHDA- 2014/12/23 06:00
CRDT- 2014/03/25 06:00
PHST- 2013/05/24 00:00 [received]
PHST- 2013/07/26 00:00 [revised]
PHST- 2013/10/19 00:00 [accepted]
PHST- 2014/03/25 06:00 [entrez]
PHST- 2014/03/25 06:00 [pubmed]
PHST- 2014/12/23 06:00 [medline]
AID - S0028-3770(14)00008-3 [pii]
AID - 10.1016/j.neuchi.2013.10.123 [doi]
PST - ppublish
SO  - Neurochirurgie. 2014 Feb-Apr;60(1-2):27-32. doi: 10.1016/j.neuchi.2013.10.123. 
      Epub 2014 Mar 20.