PMID- 24667068
OWN - NLM
STAT- MEDLINE
DCOM- 20150226
LR  - 20180813
IS  - 1755-3768 (Electronic)
IS  - 1755-375X (Linking)
VI  - 92
IP  - 6
DP  - 2014 Sep
TI  - Plasma vitamin D and serum total immunoglobulin E levels in patients with 
      seasonal allergic conjunctivitis.
PG  - e443-6
LID - 10.1111/aos.12398 [doi]
AB  - PURPOSE: To evaluate plasma 25-hydroxyvitamin D and serum total immunoglobulin E 
      (IgE) levels in patients with seasonal allergic conjunctivitis (SAC). METHODS: 
      This observational case-control study involved 49 patients with SAC without any 
      other ocular and systemic diseases, and 44 consecutive, age- and sex-matched 
      healthy subjects. Plasma 25-hydroxyvitamin D and serum total IgE levels of all 
      subjects were quantified with electrochemiluminescence technique. Results were 
      compared between the groups, and p values of <0.05 were considered as 
      statistically significant. RESULTS: No significant differences were found between 
      the groups with respect to age (p = 0.41) and sex (p = 0.98). Plasma vitamin D 
      levels of the subjects with SAC (median 8.03 ng/ml, range 3.00-17.97 ng/ml) were 
      significantly lower than the control group (median 10.52 ng/ml, range 
      3.30-25.92 ng/ml) (p = 0.007). Serum total IgE levels of patients with SAC 
      (median 48.65 IU/ml, range 1.77-812.00 IU/ml) were significantly higher when 
      compared to the control group (median 32.49 IU/ml, range 0.14-104.60 IU/ml) 
      (p = 0.003). CONCLUSIONS: We found lower plasma vitamin D levels and higher serum 
      total IgE levels in patients with SAC.
CI  - (c) 2014 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & 
      Sons Ltd.
FAU - Dadaci, Zeynep
AU  - Dadaci Z
AD  - Department of Ophthalmology, Mevlana (Rumi) University School of Medicine, Meram, 
      Konya, Turkey.
FAU - Borazan, Mehmet
AU  - Borazan M
FAU - Kiyici, Aysel
AU  - Kiyici A
FAU - Oncel Acir, Nursen
AU  - Oncel Acir N
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20140326
PL  - England
TA  - Acta Ophthalmol
JT  - Acta ophthalmologica
JID - 101468102
RN  - 1406-16-2 (Vitamin D)
RN  - 37341-29-0 (Immunoglobulin E)
RN  - A288AR3C9H (25-hydroxyvitamin D)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Age Distribution
MH  - Case-Control Studies
MH  - Child
MH  - Conjunctivitis, Allergic/*blood
MH  - Female
MH  - Humans
MH  - Immunoglobulin E/*blood
MH  - Luminescent Measurements
MH  - Male
MH  - Prospective Studies
MH  - Sex Distribution
MH  - Vitamin D/*analogs & derivatives/blood
MH  - Young Adult
OTO - NOTNLM
OT  - allergy
OT  - immunoglobulin E
OT  - seasonal allergic conjunctivitis
OT  - vitamin D
EDAT- 2014/03/29 06:00
MHDA- 2015/02/27 06:00
CRDT- 2014/03/27 06:00
PHST- 2013/12/29 00:00 [received]
PHST- 2014/02/16 00:00 [accepted]
PHST- 2014/03/27 06:00 [entrez]
PHST- 2014/03/29 06:00 [pubmed]
PHST- 2015/02/27 06:00 [medline]
AID - 10.1111/aos.12398 [doi]
PST - ppublish
SO  - Acta Ophthalmol. 2014 Sep;92(6):e443-6. doi: 10.1111/aos.12398. Epub 2014 Mar 26.