PMID- 24669687
OWN - NLM
STAT- MEDLINE
DCOM- 20140919
LR  - 20190221
IS  - 2096-7993 (Print)
IS  - 2096-7993 (Linking)
VI  - 27
IP  - 24
DP  - 2013 Dec
TI  - [The treatment and clinical therapeutic effect analysis in 59 cases of advanced 
      supraglottic laryngeal squamous cell carcinoma].
PG  - 1366-9
AB  - OBJECTIVE: To compare the therapeutic effect of postoperative radiotherapy with 
      surgery alone in advanced supraglottic laryngeal squamous cell carcinoma (LSCC). 
      METHOD: According to the treatment methods, 59 patients with advanced 
      supraglottic LSCC were divided into surgery plus radiotherapy group (S+R group) 
      (33 cases) and surgical group (S group) (26 cases). In S+R group, total 
      laryngectomy was performed on 27 patients and partial laryngectomy on 6 patients, 
      27 of whom underwent lateral neck dissections; while in S group, total 
      laryngectomy was performed on 23 patients and partial laryngectomy on 3 patients, 
      24 of whom underwent lateral neck dissections. RESULT: The 3-year overall 
      survival rate of S+R and S group were 62.6% and 62.6% respectively, and the 
      5-year overall survival rate of S+R and S group were 43.8% and 40.5% 
      respectively. But there was no statistically significant difference of survival 
      rate between two groups by Log-rank test (P > 0.05). In S+R group, recurrence 
      happened in 5 cases and the recurrent rate was 15.1%; in S group, recurrence 
      happened in 10 patients and the recurrent rate was 38.5%, statistically 
      significant difference was found between the two recurrent rates (P < 0.05). 
      CONCLUSION: Surgery combined with postoperative radiotherapy could not improve 
      the 3-year-or 5-year overall survival rate, but could significantly reduced tumor 
      recurrence rate.
FAU - Lai, Qimin
AU  - Lai Q
FAU - Li, Hao
AU  - Li H
LA  - chi
PT  - Comparative Study
PT  - Journal Article
PL  - China
TA  - Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
JT  - Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical 
      otorhinolaryngology, head, and neck surgery
JID - 101303164
SB  - IM
MH  - Adult
MH  - Aged
MH  - Carcinoma, Squamous Cell/pathology/*radiotherapy/*surgery
MH  - Combined Modality Therapy
MH  - Female
MH  - Glottis/pathology
MH  - Head and Neck Neoplasms/pathology/*radiotherapy/*surgery
MH  - Humans
MH  - Laryngeal Neoplasms/pathology/*radiotherapy/*surgery
MH  - Laryngectomy
MH  - Male
MH  - Middle Aged
MH  - Neck Dissection
MH  - Squamous Cell Carcinoma of Head and Neck
MH  - Survival Rate
MH  - Treatment Outcome
EDAT- 2014/03/29 06:00
MHDA- 2014/09/23 06:00
CRDT- 2014/03/28 06:00
PHST- 2014/03/28 06:00 [entrez]
PHST- 2014/03/29 06:00 [pubmed]
PHST- 2014/09/23 06:00 [medline]
PST - ppublish
SO  - Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2013 Dec;27(24):1366-9.