PMID- 24669716
OWN - NLM
STAT- MEDLINE
DCOM- 20150708
LR  - 20190923
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 31
IP  - 12
DP  - 2013 Dec
TI  - [Determination of the total amount of maleic acid and maleic anhydride in starch 
      and its products by high performance liquid chromatography-tandem mass 
      spectrometry].
PG  - 1224-7
AB  - A high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/ MS) 
      method was established for the determination of the total amount of maleic acid 
      and maleic anhydride in starch and its products. The samples were extracted with 
      50% (v/v) methanol and hydrolyzed by alkaline, then analyzed by HPLC-MS/MS, and 
      quantified with the external standard method. The mass spectrometry was operated 
      with electrospray in negative ionization mode. The multiple reaction monitoring 
      (MRM) mode was employed involving the transition of the precursor ion to two 
      selected product ions, in which one pair was for quantification (m/z 115.0 > 
      71.1) and the other pair was for identification (m/z 115.0 > 27.1). The results 
      indicated that no significant matrix effect was found for the spiked samples. The 
      recoveries of maleic acid spiked in starch and its products were 80.2%-115.3% at 
      spiked levels of 0.5-1,000 mg/kg. The relative standard deviations (RSDs) were 
      less than 12% (n = 6). The limits of detection (LOD) and quantification (LOQ) 
      were 0.1 and 0.5 mg/kg for maleic acid and maleic anhydride, respectively. The 
      method is rapid, sensitive and reproducible for the determination of the total 
      amount of maleic acid and maleic anhydride in starch and its products and shows 
      great potential for routine analysis
FAU - Xu, Dunming
AU  - Xu D
FAU - Chen, Yan
AU  - Chen Y
FAU - Zhou, Shuang
AU  - Zhou S
FAU - Lian, Yingjie
AU  - Lian Y
FAU - Chen, Luping
AU  - Chen L
FAU - Lin, Liyi
AU  - Lin L
FAU - Zhou, Yu
AU  - Zhou Y
FAU - Huang, Zhiqiang
AU  - Huang Z
LA  - chi
PT  - Journal Article
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Maleates)
RN  - 0 (Maleic Anhydrides)
RN  - 9005-25-8 (Starch)
RN  - 91XW058U2C (maleic acid)
SB  - IM
MH  - *Chromatography, High Pressure Liquid
MH  - Limit of Detection
MH  - Maleates/*analysis
MH  - Maleic Anhydrides/*analysis
MH  - Starch/*analysis
MH  - *Tandem Mass Spectrometry
EDAT- 2014/03/29 06:00
MHDA- 2015/07/15 06:00
CRDT- 2014/03/28 06:00
PHST- 2014/03/28 06:00 [entrez]
PHST- 2014/03/29 06:00 [pubmed]
PHST- 2015/07/15 06:00 [medline]
AID - 10.3724/sp.j.1123.2013.07011 [doi]
PST - ppublish
SO  - Se Pu. 2013 Dec;31(12):1224-7. doi: 10.3724/sp.j.1123.2013.07011.