PMID- 24670879
OWN - NLM
STAT- MEDLINE
DCOM- 20150212
LR  - 20190819
IS  - 1347-4820 (Electronic)
IS  - 1346-9843 (Linking)
VI  - 78
IP  - 6
DP  - 2014
TI  - Impact of concomitant surgical atrial fibrillation ablation in patients 
      undergoing aortic valve replacement.
PG  - 1364-71
AB  - BACKGROUND: The clinical benefit of concomitant atrial fibrillation (AF) ablation 
      at the time of aortic valve replacement (AVR) is uncertain. METHODS AND RESULTS: 
      A total of 124 patients with AF who underwent AVR with (n=50) or without (n=74) a 
      concomitant maze procedure, between 2000 and 2011, were evaluated. There were no 
      significant differences in early postoperative outcomes. During a median clinical 
      follow-up of 18.1 months (interquartile range: 6.9-47.8 months), 19 late deaths 
      (15.3%) and 33 valve-related complications (26.6%) occurred, but the differences 
      between groups were not statistically significant. Major event-free survival at 5 
      years was 60.9+/-9.9% vs. 57.0+/-10.3% (P=0.41). After adjustment, the maze group 
      demonstrated similar risks for major adverse cardiac events (hazard ratio, 1.18; 
      95% confidence interval, 0.56-2.49; P=0.67). However, the rate of sinus rhythm 
      restoration at 4 years was significantly higher in the maze group (80.6% vs. 
      3.6%, P<0.001). Left atrial dimension was smaller (46.9 vs. 50.4mm, P=0.017), and 
      the ejection fraction was higher (60.6% vs. 58.0%, P=0.059) in the maze group. 
      The rate of postoperative anticoagulation was also lower in the maze group (53.1% 
      vs. 89.2%, P<0.001). CONCLUSIONS: Concomitant AF ablation in patients undergoing 
      AVR resulted in increased sinus rhythm restoration, better echocardiographic 
      results, and decreased anticoagulation requirement, without increasing surgical 
      morbidity or mortality.
FAU - Yoo, Jae Suk
AU  - Yoo JS
AD  - Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, 
      University of Ulsan College of Medicine.
FAU - Kim, Joon Bum
AU  - Kim JB
FAU - Ro, Sun Kyun
AU  - Ro SK
FAU - Jung, Yoonsuh
AU  - Jung Y
FAU - Jung, Sung-Ho
AU  - Jung SH
FAU - Choo, Suk Jung
AU  - Choo SJ
FAU - Lee, Jae Won
AU  - Lee JW
FAU - Chung, Cheol Hyun
AU  - Chung CH
LA  - eng
PT  - Journal Article
DEP - 20140326
PL  - Japan
TA  - Circ J
JT  - Circulation journal : official journal of the Japanese Circulation Society
JID - 101137683
SB  - IM
MH  - Ablation Techniques/*methods
MH  - Aged
MH  - Aortic Valve/*surgery
MH  - *Atrial Fibrillation/mortality/physiopathology/surgery
MH  - Disease-Free Survival
MH  - Female
MH  - Heart Valve Prosthesis Implantation/*methods
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Survival Rate
EDAT- 2014/03/29 06:00
MHDA- 2015/02/13 06:00
CRDT- 2014/03/28 06:00
PHST- 2014/03/28 06:00 [entrez]
PHST- 2014/03/29 06:00 [pubmed]
PHST- 2015/02/13 06:00 [medline]
AID - DN/JST.JSTAGE/circj/CJ-13-1533 [pii]
AID - 10.1253/circj.cj-13-1533 [doi]
PST - ppublish
SO  - Circ J. 2014;78(6):1364-71. doi: 10.1253/circj.cj-13-1533. Epub 2014 Mar 26.