PMID- 2467295
OWN - NLM
STAT- MEDLINE
DCOM- 19890428
LR  - 20190501
IS  - 0027-8424 (Print)
IS  - 1091-6490 (Electronic)
IS  - 0027-8424 (Linking)
VI  - 86
IP  - 6
DP  - 1989 Mar
TI  - Comparison of a human T-cell lymphotropic virus type I strain from cerebrospinal 
      fluid of a Jamaican patient with tropical spastic paraparesis with a prototype 
      human T-cell lymphotropic virus type I.
PG  - 2021-5
AB  - The isolation and characterization of a human T-cell lymphotropic retrovirus 
      related to human T-cell lymphotropic virus type I (HTLV-I) from cerebrospinal 
      fluid of a Jamaican patient with tropical spastic paraparesis is described. The 
      virus isolate is a typical type C retrovirus as seen by electron microscopy and 
      is related to prototype HTLV-I isolated from patients with adult T-cell leukemia 
      but is not identical to this prototype HTLV-I as seen by restriction enzyme 
      mapping.
FAU - Sarin, P S
AU  - Sarin PS
AD  - Laboratory of Tumor Cell Biology, National Cancer Institute, Bethesda, MD 20892.
FAU - Rodgers-Johnson, P
AU  - Rodgers-Johnson P
FAU - Sun, D K
AU  - Sun DK
FAU - Thornton, A H
AU  - Thornton AH
FAU - Morgan, O S
AU  - Morgan OS
FAU - Gibbs, W N
AU  - Gibbs WN
FAU - Mora, C
AU  - Mora C
FAU - McKhann, G 2nd
AU  - McKhann G 2nd
FAU - Gajdusek, D C
AU  - Gajdusek DC
FAU - Gibbs, C J Jr
AU  - Gibbs CJ Jr
LA  - eng
PT  - Case Reports
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - Proc Natl Acad Sci U S A
JT  - Proceedings of the National Academy of Sciences of the United States of America
JID - 7505876
RN  - 0 (DNA, Viral)
RN  - 0 (Deltaretrovirus Antibodies)
RN  - EC 2.7.7.49 (RNA-Directed DNA Polymerase)
RN  - EC 3.1.21.- (DNA Restriction Enzymes)
SB  - IM
MH  - Aged
MH  - Cells, Cultured
MH  - Cerebrospinal Fluid/*microbiology
MH  - DNA Restriction Enzymes
MH  - DNA, Viral/analysis
MH  - Deltaretrovirus Antibodies/analysis
MH  - Female
MH  - Fluorescent Antibody Technique
MH  - Human T-lymphotropic virus 1/enzymology/genetics/*isolation & purification
MH  - Humans
MH  - Jamaica
MH  - Leukemia, T-Cell/microbiology
MH  - Leukocytes, Mononuclear/microbiology
MH  - Microscopy, Electron
MH  - Paraparesis, Tropical Spastic/immunology/*microbiology
MH  - RNA-Directed DNA Polymerase/analysis
PMC - PMC286838
EDAT- 1989/03/01 00:00
MHDA- 2001/03/28 10:01
PMCR- 1989/09/01
CRDT- 1989/03/01 00:00
PHST- 1989/03/01 00:00 [pubmed]
PHST- 2001/03/28 10:01 [medline]
PHST- 1989/03/01 00:00 [entrez]
PHST- 1989/09/01 00:00 [pmc-release]
AID - 10.1073/pnas.86.6.2021 [doi]
PST - ppublish
SO  - Proc Natl Acad Sci U S A. 1989 Mar;86(6):2021-5. doi: 10.1073/pnas.86.6.2021.