PMID- 24673641
OWN - NLM
STAT- MEDLINE
DCOM- 20141224
LR  - 20181202
IS  - 1551-3823 (Electronic)
IS  - 1551-3815 (Linking)
VI  - 33
IP  - 3
DP  - 2014 Jun
TI  - The evaluation of inflammatory markers in umbilical cord blood.
PG  - 196-7
LID - 10.3109/15513815.2014.898722 [doi]
AB  - We have read with great interest the article by Lausten-Thomsen et al. entitled 
      "Inflammatory Markers in Umbilical Cord Blood from Small-For-Gestational-Age 
      Newborns" in which they report Interleukin 6 (IL-6), Tumor necrosis factor-alpha 
      (TNF-alpha) and C-reactive protein (CRP) levels in umbilical cord blood from 
      small-for-gestational-age (SGA) and healthy newborns. In this regard, we would 
      like to make some additions to paper in respect to interpretations of biochemical 
      markers. Normal CRP concentration in healthy human serum is usually lower than 10 
      mg/L, slightly increasing with aging. Acute inflammatory response causes release 
      of IL-6 and other cytokines that trigger the synthesis of CRP by the liver. In 
      this article, IL-6 levels reported as elevated but CRP levels have remained in 
      normal range. In this situation, increasing in IL-6 levels should be approached 
      suspiciously. Although decreased TNF-alpha level was compatible with IL-6 levels, 
      increased IL-6 levels did not cause CRP elevation in this study.
FAU - Aydin, Ibrahim
AU  - Aydin I
AD  - 1Department of Biochemistry, Sarikamis Military Hospital, Kars, Turkey.
FAU - Aydin, Fevzi Nuri
AU  - Aydin FN
FAU - Agilli, Mehmet
AU  - Agilli M
LA  - eng
PT  - Comment
PT  - Letter
DEP - 20140327
PL  - England
TA  - Fetal Pediatr Pathol
JT  - Fetal and pediatric pathology
JID - 101230972
RN  - 0 (Inflammation Mediators)
SB  - IM
CON - Fetal Pediatr Pathol. 2014 Apr;33(2):114-8. PMID: 24476425
MH  - Female
MH  - Fetal Blood/*metabolism
MH  - Humans
MH  - Infant, Small for Gestational Age/*blood
MH  - Inflammation Mediators/*blood
MH  - Male
MH  - Pregnancy
EDAT- 2014/03/29 06:00
MHDA- 2014/12/30 06:00
CRDT- 2014/03/29 06:00
PHST- 2014/03/29 06:00 [entrez]
PHST- 2014/03/29 06:00 [pubmed]
PHST- 2014/12/30 06:00 [medline]
AID - 10.3109/15513815.2014.898722 [doi]
PST - ppublish
SO  - Fetal Pediatr Pathol. 2014 Jun;33(3):196-7. doi: 10.3109/15513815.2014.898722. 
      Epub 2014 Mar 27.