PMID- 24673784
OWN - NLM
STAT- MEDLINE
DCOM- 20150806
LR  - 20181202
IS  - 1532-8228 (Electronic)
IS  - 0883-9417 (Linking)
VI  - 28
IP  - 2
DP  - 2014 Apr
TI  - Peripheral brain derived neurotrophic factor (BDNF) in bulimia nervosa: a 
      systematic review.
PG  - 108-13
LID - S0883-9417(13)00149-0 [pii]
LID - 10.1016/j.apnu.2013.11.006 [doi]
AB  - INTRODUCTION: Currently, there is limited understanding of the etiology of BN. 
      While multifaceted etiology is likely, several neurobiological factors may play a 
      role. Brain derived neurotrophic factor (BDNF), a potential biomarker linked to 
      eating and weight disorders, is one factor of recent investigation. This paper 
      examined studies comparing BDNF blood levels in BN to healthy control (HC) 
      subjects. METHODS: A systematic review of the literature was conducted utilizing 
      five databases (PubMed, CINAHL, EMBASE, PsycINFO, and Medline). Key terms 
      included eating disorders, BDNF, and bulimia nervosa. CONCLUSIONS: BDNF blood 
      levels appear lower in BN than in HC subjects; however, studies are needed to 
      examine the influence of possible correlates including symptom severity, mood, 
      medications, exercise, and substance use.
CI  - Copyright (c) 2014 Elsevier Inc. All rights reserved.
FAU - Phillips, Kathryn
AU  - Phillips K
AD  - Fairfield University, Fairfield, CT. Electronic address: 
      Kphillips1@fairfield.edu.
FAU - Keane, Kathleen
AU  - Keane K
AD  - Boston College, Chestnut Hill, MA; Richards 1, Maine Medical Center, Portland, 
      ME. Electronic address: keanekd@bc.edu.
FAU - Wolfe, Barbara E
AU  - Wolfe BE
AD  - Boston College, Chestnut Hill, MA. Electronic address: Barabara.wolfe.1@bc.edu.
LA  - eng
PT  - Journal Article
PT  - Review
PT  - Systematic Review
DEP - 20131123
PL  - United States
TA  - Arch Psychiatr Nurs
JT  - Archives of psychiatric nursing
JID - 8708534
RN  - 0 (Brain-Derived Neurotrophic Factor)
SB  - IM
MH  - Animals
MH  - Brain-Derived Neurotrophic Factor/*blood/physiology
MH  - Bulimia Nervosa/*blood/*etiology/pathology
MH  - Humans
EDAT- 2014/03/29 06:00
MHDA- 2015/08/08 06:00
CRDT- 2014/03/29 06:00
PHST- 2013/07/06 00:00 [received]
PHST- 2013/11/10 00:00 [revised]
PHST- 2013/11/11 00:00 [accepted]
PHST- 2014/03/29 06:00 [entrez]
PHST- 2014/03/29 06:00 [pubmed]
PHST- 2015/08/08 06:00 [medline]
AID - S0883-9417(13)00149-0 [pii]
AID - 10.1016/j.apnu.2013.11.006 [doi]
PST - ppublish
SO  - Arch Psychiatr Nurs. 2014 Apr;28(2):108-13. doi: 10.1016/j.apnu.2013.11.006. Epub 
      2013 Nov 23.