PMID- 24678570
OWN - NLM
STAT- MEDLINE
DCOM- 20140818
LR  - 20140331
IS  - 1538-957X (Electronic)
IS  - 1538-9588 (Linking)
VI  - 15
IP  - 5
DP  - 2014
TI  - Elevated risk of sleepiness-related motor vehicle accidents in patients with 
      obstructive sleep apnea syndrome: a case-control study.
PG  - 470-6
LID - 10.1080/15389588.2013.830213 [doi]
AB  - OBJECTIVES: The present case-control study aimed to determine whether obstructive 
      sleep apnea syndrome (OSAS) patients are at an increased risk for 
      sleepiness-related motor vehicle accidents (MVAs) than controls and to identify 
      disease-related factors associated with accident risk. METHODS: Demographic, 
      anthropometric, clinical, and polysomnographic parameters of 312 OSAS patients 
      were compared with 156 age- and sex-matched primary snoring subjects. RESULTS: 
      The rate of OSAS patients reporting accident was higher than snoring subjects 
      (21.2% vs. 11.5%, P = .011), and OSAS was associated with an increase in accident 
      risk (odds ratio = 2.06, 95% confidence interval [CI], 1.17 to 3.61, P = .012). 
      Younger OSAS patients (P = .001) and those who were male (P = .001), had greater 
      neck circumference (P = .002), had a higher Epworth sleepiness score (ESS; P < 
      .0001), and had a higher apnea-hypopnea index (AHI; p = .039) had more MVAs than 
      OSAS patients. Daytime sleepiness was associated with a 2.74-fold increase (95% 
      CI, 1.54 to 4.87, P = .001) in accident risk. In multiple logistic regression 
      analysis, accident risk was associated with neck circumference (P < .031) and ESS 
      (P < .0001). In addition, accident risk could be excluded in OSAS patients with 
      neck circumference < 43 cm and ESS < 11 (sensitivity 33.3%, specificity 85.8%). 
      CONCLUSIONS: The present results show that OSAS patients have a twofold higher 
      risk of traffic accidents than control subjects, and increased neck circumference 
      and excessive daytime sleepiness are useful in predicting OSAS patients at higher 
      risk of having accidents.
FAU - Basoglu, Ozen K
AU  - Basoglu OK
AD  - a Department of Chest Diseases , Ege University School of Medicine , Izmir , 
      Turkey.
FAU - Tasbakan, Mehmet Sezai
AU  - Tasbakan MS
LA  - eng
PT  - Journal Article
PL  - England
TA  - Traffic Inj Prev
JT  - Traffic injury prevention
JID - 101144385
SB  - IM
MH  - Accidents, Traffic/*statistics & numerical data
MH  - Adult
MH  - Case-Control Studies
MH  - Disorders of Excessive Somnolence/*epidemiology
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Neck/anatomy & histology
MH  - Retrospective Studies
MH  - Risk Assessment
MH  - Sleep Apnea, Obstructive/*complications
EDAT- 2014/04/01 06:00
MHDA- 2014/08/19 06:00
CRDT- 2014/04/01 06:00
PHST- 2014/04/01 06:00 [entrez]
PHST- 2014/04/01 06:00 [pubmed]
PHST- 2014/08/19 06:00 [medline]
AID - 10.1080/15389588.2013.830213 [doi]
PST - ppublish
SO  - Traffic Inj Prev. 2014;15(5):470-6. doi: 10.1080/15389588.2013.830213.