PMID- 24684117
OWN - NLM
STAT- MEDLINE
DCOM- 20140529
LR  - 20161020
IS  - 1000-0607 (Print)
IS  - 1000-0607 (Linking)
VI  - 39
IP  - 1
DP  - 2014 Feb
TI  - [Toll-like receptor 4 in regional acupoints and initiation of acupuncture 
      signals].
PG  - 79-82
AB  - It has been well documented that acupuncture effect is produced through suitable 
      manipulation stimulation of the inserted acupuncture needle, and subsequent 
      activation of the body' s inherent nerve-endocrine-immune regulating network. As 
      a physical stimulus, the acupuncture stimulation exerted onto the local acupoint 
      needs being converted into biological signal first, further reaching favorable 
      regulation in the body. Toll-like receptor 4 (TLR 4), an important molecular 
      pattern recognition receptor, can not only recognize the exogenous 
      pathogen-associated molecular patterns but also identify endogenous 
      damage-associated molecular patterns, leading to activation of innate immunity. 
      What's more, TLR 4 has a close relationship with nervous and immune system of the 
      body. In the present paper, the authors make a discussion on the correlation 
      between TLR 4 and acupuncture intervention from 1) TLR 4 and acupuncture signal 
      conversion, 2) TLR 4 and acupuncture clinical phenomenon, and 3) TLR 4 and 
      related mechanisms of acupuncture intervention. Moreover, the authors also think 
      that TLR 4 in the acupoint area may participate in the initiation process of 
      acupuncture stimulation information.
FAU - Cui, Rui
AU  - Cui R
FAU - Xi, Qiang
AU  - Xi Q
LA  - chi
PT  - English Abstract
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Zhen Ci Yan Jiu
JT  - Zhen ci yan jiu = Acupuncture research
JID - 8507710
RN  - 0 (Toll-Like Receptor 4)
SB  - IM
MH  - Acupuncture Points
MH  - *Acupuncture Therapy
MH  - Animals
MH  - Humans
MH  - Immunity
MH  - *Signal Transduction
MH  - Toll-Like Receptor 4/genetics/*metabolism
EDAT- 2014/04/02 06:00
MHDA- 2014/05/30 06:00
CRDT- 2014/04/02 06:00
PHST- 2014/04/02 06:00 [entrez]
PHST- 2014/04/02 06:00 [pubmed]
PHST- 2014/05/30 06:00 [medline]
PST - ppublish
SO  - Zhen Ci Yan Jiu. 2014 Feb;39(1):79-82.