PMID- 24686116
OWN - NLM
STAT- MEDLINE
DCOM- 20150223
LR  - 20140704
IS  - 1878-3252 (Electronic)
IS  - 0946-672X (Linking)
VI  - 28
IP  - 3
DP  - 2014 Jul
TI  - The prevalence of wheezing and its association with serum zinc concentration in 
      children and adolescents in Brazil.
PG  - 293-7
LID - S0946-672X(14)00018-2 [pii]
LID - 10.1016/j.jtemb.2014.02.007 [doi]
AB  - OBJECTIVE: To assess the influence of zinc serum status on the prevalence of 
      wheezing in a sample of children and adolescents in Northeastern Brazil. RESEARCH 
      METHODS AND PROCEDURES: This is a cross-sectional study which included 592 
      students of 6-12 years old, from the public elementary schools of Sao Francisco 
      do Conde, Bahia, Northeastern Brazil. Report of wheezing in the past 12 months 
      was collected using a questionnaire of the International Study of Asthma and 
      Allergies in Childhood Program (ISAAC) phase III, adapted to Portuguese. The 
      determination of serum Zn levels was performed using a flame atomic absorption 
      spectrometer. Data on anthropometric status, level of physical activity, pubertal 
      development and socioeconomic information, for each participant were obtained. 
      Multivariate logistic regression analyses were used to assess the associations of 
      interest. RESULTS: Of the students, 8.6% (95% CI 6.30-10.9) reported having 
      wheezing. The mean (SD) serum zinc level was 114 (22.9 mug/dL). The results of the 
      multiple logistic regression analysis showed, after adjustments, positive and 
      significant association between low serum zinc levels and wheezing. Students 
      categorized as being below the median for serum Zn concentration presented an 
      almost 1.9-fold increase in the wheezing prevalence ratio (OR=1.9; 95% CI 
      1.03-3.53). CONCLUSION: The main findings of this study suggest that the level of 
      zinc may influence the risk of wheezing in late childhood on the study 
      population.
CI  - Copyright (c) 2014 Elsevier GmbH. All rights reserved.
FAU - de Cassia Ribeiro-Silva, Rita
AU  - de Cassia Ribeiro-Silva R
AD  - Departamento de Ciencias da Nutricao, Universidade Federal da Bahia, Av. Araujo 
      Pinho, 32, Canela, CEP: 40110-150 Salvador, Bahia, Brazil. Electronic address: 
      rcrsilva@ufba.br.
FAU - Fiaccone, Rosemeire Leovigildo
AU  - Fiaccone RL
AD  - Instituto de Matematica, Universidade Federal da Bahia, Av. Adhemar de Barros, 
      s/n, Ondina, CEP: 40170-110 Salvador, Bahia, Brazil.
FAU - Barreto, Mauricio Lima
AU  - Barreto ML
AD  - Instituto de Saude Coletiva, Universidade Federal da Bahia, Rua Basilio da Gama, 
      s/n, Campus Universitario Canela, CEP: 40110-040 Salvador, Bahia, Brazil.
FAU - da Silva, Luce Alves
AU  - da Silva LA
AD  - Departamento de Ciencias da Nutricao, Universidade Federal da Bahia, Av. Araujo 
      Pinho, 32, Canela, CEP: 40110-150 Salvador, Bahia, Brazil.
FAU - Santos, Luis Fernandes Pereira
AU  - Santos LF
AD  - Departamento de Ciencias da Nutricao, Universidade Federal da Bahia, Av. Araujo 
      Pinho, 32, Canela, CEP: 40110-150 Salvador, Bahia, Brazil.
FAU - Alcantara-Neves, Neuza Maria
AU  - Alcantara-Neves NM
AD  - Departamento de Ciencias da Biointeracao, Instituto de Ciencias da Saude, 
      Universidade Federal da Bahia, Av. Reitor Miguel Calmon, s/n, CEP: 40110-100 
      Salvador, Bahia, Brazil.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140310
PL  - Germany
TA  - J Trace Elem Med Biol
JT  - Journal of trace elements in medicine and biology : organ of the Society for 
      Minerals and Trace Elements (GMS)
JID - 9508274
RN  - J41CSQ7QDS (Zinc)
SB  - IM
MH  - Asthma/blood/physiopathology
MH  - Child
MH  - Cross-Sectional Studies
MH  - Female
MH  - Humans
MH  - Male
MH  - Respiratory Sounds/*physiology
MH  - Zinc/*blood
OTO - NOTNLM
OT  - Adolescents
OT  - Children
OT  - Nutrition
OT  - Serum zinc levels
OT  - Wheezing
EDAT- 2014/04/02 06:00
MHDA- 2015/02/24 06:00
CRDT- 2014/04/02 06:00
PHST- 2013/11/26 00:00 [received]
PHST- 2014/02/26 00:00 [revised]
PHST- 2014/02/28 00:00 [accepted]
PHST- 2014/04/02 06:00 [entrez]
PHST- 2014/04/02 06:00 [pubmed]
PHST- 2015/02/24 06:00 [medline]
AID - S0946-672X(14)00018-2 [pii]
AID - 10.1016/j.jtemb.2014.02.007 [doi]
PST - ppublish
SO  - J Trace Elem Med Biol. 2014 Jul;28(3):293-7. doi: 10.1016/j.jtemb.2014.02.007. 
      Epub 2014 Mar 10.