PMID- 24691719
OWN - NLM
STAT- MEDLINE
DCOM- 20150416
LR  - 20191210
IS  - 1618-2650 (Electronic)
IS  - 1618-2642 (Linking)
VI  - 406
IP  - 12
DP  - 2014 May
TI  - Simultaneous determination of chlorpyrifos and 3,5,6-trichloro-2-pyridinol in 
      duck muscle by modified QuEChERS coupled to gas chromatography tandem mass 
      spectrometry (GC-MS/MS).
PG  - 2899-907
LID - 10.1007/s00216-014-7717-8 [doi]
AB  - A rapid, specific, and sensitive method based on modified quick, easy, cheap, 
      effective, rugged, and safe (QuEChERS) coupled to gas chromatography tandem mass 
      spectrometry (GC-MS/MS) was developed and validated for simultaneous 
      determination of chlorpyrifos (CP) and its metabolite 3,5,6-trichloro-2-pyridinol 
      (TCP) in duck muscle. The residues of CP and TCP were extracted by acidified 
      acetonitrile. The fat layer of the extract was removed under -20  degrees C, then the 
      organic layer was evaporated. The analytes were derivatized by 
      N-(tert-butyldimethylsilyl)-N-methyltrifluoroacetamide (MTBSTFA) and cleaned up 
      by a mixture of 150 mg MgSO4, 25 mg graphitized carbon black (GCB), and 50 mg 
      N-propylethylenediamine (PSA) to remove interference. The final extract was 
      analyzed by GC-MS/MS. Recovery values at the spiking concentrations ranged from 
      86.2 to 92.3 % for CP and from 74.8 to 81.8 % for TCP, with relative standard 
      deviations (RSDs) lower than 9.5 and 12.3, respectively. The correlation 
      coefficients of CP (from 2 to 2,000 mug/kg) and TCP (from 1 to 1,000 mug/kg) were 
      equal to or higher than 0.998. The limits of detection (LODs) were 0.3 and 0.15 
      mug/kg, and the limits of quantification (LOQs) were 1.0 and 0.5 mug/kg for CP and 
      TCP in duck muscle, respectively. The average intra- and inter-day accuracy 
      ranged from 84.6 to 91.2 % for CP and 75.6 to 82.3 % for TCP, and the intra- and 
      inter-day precisions were from 5.8 to 8.2 % for CP and 6.5 to 11.9 % for TCP. 
      Furthermore, the CP and TCP residues in duck muscle samples were detected for 
      dietary risk assessment using the validated method.
FAU - Li, Rui
AU  - Li R
AD  - State Key Laboratory Breeding Base for Zhejiang Sustainable Plant Pest Control; 
      Agricultural Ministry Key Laboratory for Pesticide Residue Detection; Zhejiang 
      Province Key Laboratory for Food Safety; Institute of Quality and Standard for 
      Agro-products, Zhejiang Academy of Agricultural Sciences, 310021, Hangzhou, 
      Zhejiang, China.
FAU - He, Liang
AU  - He L
FAU - Zhou, Ting
AU  - Zhou T
FAU - Ji, Xiaofeng
AU  - Ji X
FAU - Qian, Mingrong
AU  - Qian M
FAU - Zhou, Yu
AU  - Zhou Y
FAU - Wang, Qiang
AU  - Wang Q
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140402
PL  - Germany
TA  - Anal Bioanal Chem
JT  - Analytical and bioanalytical chemistry
JID - 101134327
RN  - 0 (Pesticides)
RN  - 0 (Pyridones)
RN  - 6515-38-4 (3,5,6-trichloro-2-pyridinol)
RN  - JCS58I644W (Chlorpyrifos)
SB  - IM
MH  - Animals
MH  - Chemical Fractionation/*methods
MH  - Chlorpyrifos/*analysis/isolation & purification
MH  - Ducks
MH  - Food Contamination/*analysis
MH  - Gas Chromatography-Mass Spectrometry/*methods
MH  - Meat/*analysis
MH  - Muscle, Skeletal/*chemistry
MH  - Pesticides/*analysis/isolation & purification
MH  - Pyridones/*analysis/isolation & purification
MH  - Tandem Mass Spectrometry/methods
EDAT- 2014/04/03 06:00
MHDA- 2015/04/17 06:00
CRDT- 2014/04/03 06:00
PHST- 2013/11/03 00:00 [received]
PHST- 2014/02/20 00:00 [accepted]
PHST- 2014/02/18 00:00 [revised]
PHST- 2014/04/03 06:00 [entrez]
PHST- 2014/04/03 06:00 [pubmed]
PHST- 2015/04/17 06:00 [medline]
AID - 10.1007/s00216-014-7717-8 [doi]
PST - ppublish
SO  - Anal Bioanal Chem. 2014 May;406(12):2899-907. doi: 10.1007/s00216-014-7717-8. 
      Epub 2014 Apr 2.