PMID- 24694746
OWN - NLM
STAT- MEDLINE
DCOM- 20151005
LR  - 20220410
IS  - 1530-0315 (Electronic)
IS  - 0195-9131 (Print)
IS  - 0195-9131 (Linking)
VI  - 46
IP  - 12
DP  - 2014 Dec
TI  - Nonexercise energy expenditure and physical activity in the Midwest Exercise 
      Trial 2.
PG  - 2286-94
LID - 10.1249/MSS.0000000000000354 [doi]
AB  - PURPOSE: This study aimed to examine compensatory changes in nonexercise energy 
      expenditure (NEEx) and nonexercise physical activity (NEPA) in response to an 
      aerobic exercise training program. METHODS: Ninety-two overweight/obese (body 
      mass index, 25-39.9 kg.m) sedentary young adults (18-30 yr) completed a 10-month 
      randomized clinical efficacy trial of aerobic exercise 5 d.wk at either 400 kcal 
      per session (n = 37), 600 kcal per session (n = 37), or control (n = 18). Total 
      daily energy expenditure (TDEE) and resting metabolic rate (RMR) were measured at 
      months 0 and 10. NEPA was measured by an accelerometer at months 0, 3.5, 7, and 
      10. NEEx was calculated by the following formula: [(total daily energy 
      expenditure x 0.9) - RMR] - net EEEx (EEEx-RMR). Mixed modeling was used to 
      examine differences between groups (group effect), within groups (time effect), 
      and group-time interaction for NEEx and NEPA. RESULTS: Within the exercise 
      groups, there were no significant effects (all P > 0.05) of group, time, or 
      group-time interaction for NEPA. In addition, there were no significant within- 
      or between-group differences for change in NEEx. However, activity counts per 
      minute were significantly higher (P < 0.001) in the 600-kcal-per-session group 
      (346 +/- 141 min.d) versus controls (290 +/- 106 min.d) at month 7 and significantly 
      higher (P < 0.001) in both the 600-kcal-per-session (345 +/- 163 min.d) and 
      400-kcal-per-session groups (317 +/- 146 min.d) versus controls (277 +/- 116 min.d) 
      at 10 months. CONCLUSIONS: A 10-month aerobic exercise training program in 
      previously sedentary, overweight and obese young adults was not associated with 
      compensatory decreases in NEEx or NEPA. Results suggest that overweight and obese 
      individuals do not become less physically active or spend more time in sedentary 
      pursuits in response to exercise.
FAU - Willis, Erik A
AU  - Willis EA
AD  - 1Department of Internal Medicine, Cardiovascular Research Institute, University 
      of Kansas Medical Center, Kansas City, KS; 2Health, Physical Education, and 
      Recreation, Augustana College, Sioux Falls, SD; and 3Institute for Measurement, 
      Methodology, Analysis, and Policy, Texas Tech University, Lubbock, TX.
FAU - Herrmann, Stephen D
AU  - Herrmann SD
FAU - Honas, Jeffery J
AU  - Honas JJ
FAU - Lee, Jaehoon
AU  - Lee J
FAU - Donnelly, Joseph E
AU  - Donnelly JE
FAU - Washburn, Richard A
AU  - Washburn RA
LA  - eng
GR  - R01 DK049181/DK/NIDDK NIH HHS/United States
GR  - R01-DK049181/DK/NIDDK NIH HHS/United States
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, N.I.H., Extramural
PL  - United States
TA  - Med Sci Sports Exerc
JT  - Medicine and science in sports and exercise
JID - 8005433
SB  - IM
MH  - Accelerometry
MH  - Adolescent
MH  - Adult
MH  - *Energy Metabolism
MH  - *Exercise Therapy
MH  - Female
MH  - Humans
MH  - Linear Models
MH  - Male
MH  - Motor Activity/*physiology
MH  - Obesity/*physiopathology/*therapy
MH  - Overweight/*physiopathology/*therapy
MH  - Sedentary Behavior
MH  - Sex Factors
MH  - Young Adult
PMC - PMC4182343
MID - NIHMS580941
COIS- Conflict of Interest The authors report no conflict of interest
EDAT- 2014/04/04 06:00
MHDA- 2015/10/06 06:00
PMCR- 2015/12/01
CRDT- 2014/04/04 06:00
PHST- 2014/04/04 06:00 [entrez]
PHST- 2014/04/04 06:00 [pubmed]
PHST- 2015/10/06 06:00 [medline]
PHST- 2015/12/01 00:00 [pmc-release]
AID - 10.1249/MSS.0000000000000354 [doi]
PST - ppublish
SO  - Med Sci Sports Exerc. 2014 Dec;46(12):2286-94. doi: 10.1249/MSS.0000000000000354.