PMID- 24696653
OWN - NLM
STAT- MEDLINE
DCOM- 20141203
LR  - 20211021
IS  - 1537-744X (Electronic)
IS  - 2356-6140 (Print)
IS  - 1537-744X (Linking)
VI  - 2014
DP  - 2014
TI  - Primary carcinoma of the fallopian tube: a review of a single institution 
      experience of 8 cases.
PG  - 630731
LID - 10.1155/2014/630731 [doi]
LID - 630731
AB  - AIMS AND OBJECTIVES: To evaluate the clinicopathologic features, response to 
      cytoreductive surgery and adjuvant platinum-based chemotherapy with or without 
      paclitaxel. MATERIALS AND METHODS: A retrospective observational study of 8 women 
      with a histopathologic diagnosis of primary fallopian tube carcinoma (PFTC) from 
      January 2000 to February 2013. RESULTS: 4/8 (50%) of the women were in the early 
      stage and an intraoperative frozen section was 100% effective in identifying 
      fallopian tube carcinoma and then a staging laparotomy was performed. All 4/8 
      cases in the early stage had received and responded to single agent carboplatin 
      and all are alive without clinical, radiological, or biochemical evidence of 
      recurrence at the end of 2 years and the longest survivor has completed 13 years. 
      Primary optimal cytoreductive surgery was achievable in 3/4 (75%) in advanced 
      disease. All showed response to adjuvant paclitaxel and carboplatin (T+C), but 
      all had succumbed to the disease following recurrence with mean progression-free 
      survival of 19 months (range 15-21 months) and mean overall survival of 27 months 
      (range 22-36 months). CONCLUSION: The pivotal role played by a frozen section in 
      diagnosing PFTC which is rare needs to be reemphasized, therefore justifying a 
      primary staging laparotomy in an early stage. Prolonged survival observed in this 
      group following an optimum tailored adjuvant single agent carboplatin is worth 
      noting.
FAU - Nanaiah, Shakuntala P
AU  - Nanaiah SP
AD  - Department of Gynaecologic Oncology, Kidwai Memorial Institute of Oncology, Dr. 
      MH MariGowda Road, Bengaluru, Karnataka 560030, India.
FAU - Rathod, Praveen S
AU  - Rathod PS
AD  - Department of Gynaecologic Oncology, Kidwai Memorial Institute of Oncology, Dr. 
      MH MariGowda Road, Bengaluru, Karnataka 560030, India.
FAU - Rajkumar, Namrata N
AU  - Rajkumar NN
AD  - Department of Pathology, Kidwai Memorial Institute of Oncology, Dr. MH MariGowda 
      Road, Bengaluru, Karnataka 560030, India.
FAU - Kundargi, Rajshekar
AU  - Kundargi R
AD  - Department of Gynaecologic Oncology, Kidwai Memorial Institute of Oncology, Dr. 
      MH MariGowda Road, Bengaluru, Karnataka 560030, India.
FAU - Subbian, Anbukkani
AU  - Subbian A
AD  - Department of Gynaecologic Oncology, Kidwai Memorial Institute of Oncology, Dr. 
      MH MariGowda Road, Bengaluru, Karnataka 560030, India.
FAU - Ramachandra, Pallavi V
AU  - Ramachandra PV
AD  - Department of Gynaecologic Oncology, Kidwai Memorial Institute of Oncology, Dr. 
      MH MariGowda Road, Bengaluru, Karnataka 560030, India.
FAU - Krishnappa, Shobha
AU  - Krishnappa S
AD  - Department of Gynaecologic Oncology, Kidwai Memorial Institute of Oncology, Dr. 
      MH MariGowda Road, Bengaluru, Karnataka 560030, India.
FAU - Narayan, Abhilasha
AU  - Narayan A
AD  - Department of Gynaecologic Oncology, Kidwai Memorial Institute of Oncology, Dr. 
      MH MariGowda Road, Bengaluru, Karnataka 560030, India.
FAU - Devi, Uma K
AU  - Devi UK
AD  - Department of Gynaecologic Oncology, Kidwai Memorial Institute of Oncology, Dr. 
      MH MariGowda Road, Bengaluru, Karnataka 560030, India.
FAU - Uttamchand, Bafna D
AU  - Uttamchand BD
AD  - Department of Gynaecologic Oncology, Kidwai Memorial Institute of Oncology, Dr. 
      MH MariGowda Road, Bengaluru, Karnataka 560030, India.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20140213
PL  - United States
TA  - ScientificWorldJournal
JT  - TheScientificWorldJournal
JID - 101131163
SB  - IM
MH  - Adult
MH  - Aged
MH  - Carcinoma/*diagnosis/drug therapy/surgery
MH  - Fallopian Tube Neoplasms/*diagnosis/drug therapy/surgery
MH  - Female
MH  - Humans
MH  - Middle Aged
MH  - Recurrence
MH  - Treatment Outcome
PMC - PMC3947731
EDAT- 2014/04/04 06:00
MHDA- 2014/12/15 06:00
PMCR- 2014/02/13
CRDT- 2014/04/04 06:00
PHST- 2013/08/24 00:00 [received]
PHST- 2013/12/10 00:00 [accepted]
PHST- 2014/04/04 06:00 [entrez]
PHST- 2014/04/04 06:00 [pubmed]
PHST- 2014/12/15 06:00 [medline]
PHST- 2014/02/13 00:00 [pmc-release]
AID - 10.1155/2014/630731 [doi]
PST - epublish
SO  - ScientificWorldJournal. 2014 Feb 13;2014:630731. doi: 10.1155/2014/630731. 
      eCollection 2014.