PMID- 24698656
OWN - NLM
STAT- MEDLINE
DCOM- 20150330
LR  - 20151119
IS  - 1439-0507 (Electronic)
IS  - 0933-7407 (Linking)
VI  - 57
IP  - 9
DP  - 2014 Sep
TI  - Paracoccidioidomycosis in Mexico: clinical and epidemiological data from 93 new 
      cases (1972-2012).
PG  - 525-30
LID - 10.1111/myc.12190 [doi]
AB  - Paracoccidioidomycosis (PCM) is an endemic systemic infection in several 
      countries of Latin America. The few registered cases in Mexico most likely do not 
      reflect the real frequency. Disseminate the epidemiological and clinical data of 
      unreported cases of PCM in Mexico from 1972 until 2012 is the aim of this work. 
      Epidemiological and clinical information of non-published cases of PCM was 
      requested from the principal mycological diagnosis centres in Mexico. A total of 
      93 cases were received. The infection was found predominantly in men (95.7%), 
      peasants (88.5%) and individual between 31 and 60 years of age. Most of the cases 
      were found in tropical areas of the Gulf of Mexico (54.84%) and the Pacific 
      littoral (20.3%). The main sites of dissemination were the oral mucosa (39.38%) 
      and skin (34.05%). The most effective treatments were itraconazole alone and the 
      combination of itraconazole with sulfamethoxazole-trimethoprim. PCM is a 
      subdiagnosed pathology in Mexico. Therefore, adequate training is necessary to 
      determine the current status of this mycosis.
CI  - (c) 2014 Blackwell Verlag GmbH.
FAU - Lopez-Martinez, Ruben
AU  - Lopez-Martinez R
AD  - Departamento de Microbiologia y Parasitologia, Facultad de Medicina, Universidad 
      Nacional Autonoma de Mexico, Mexico, D. F., Mexico.
FAU - Hernandez-Hernandez, Francisca
AU  - Hernandez-Hernandez F
FAU - Mendez-Tovar, Luis Javier
AU  - Mendez-Tovar LJ
FAU - Manzano-Gayosso, Patricia
AU  - Manzano-Gayosso P
FAU - Bonifaz, Alexandro
AU  - Bonifaz A
FAU - Arenas, Roberto
AU  - Arenas R
FAU - Padilla-Desgarennes, Maria Del Carmen
AU  - Padilla-Desgarennes Mdel C
FAU - Estrada, Roberto
AU  - Estrada R
FAU - Chavez, Guadalupe
AU  - Chavez G
LA  - eng
PT  - Journal Article
DEP - 20140402
PL  - Germany
TA  - Mycoses
JT  - Mycoses
JID - 8805008
RN  - 0 (Antifungal Agents)
RN  - 304NUG5GF4 (Itraconazole)
RN  - 8064-90-2 (Trimethoprim, Sulfamethoxazole Drug Combination)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Age Factors
MH  - Aged
MH  - Aged, 80 and over
MH  - Antifungal Agents/therapeutic use
MH  - Child
MH  - Female
MH  - Humans
MH  - Itraconazole/therapeutic use
MH  - Male
MH  - Mexico/epidemiology
MH  - Middle Aged
MH  - Mouth Mucosa/microbiology
MH  - Occupational Exposure
MH  - Paracoccidioidomycosis/drug therapy/*epidemiology/*pathology
MH  - Sex Factors
MH  - Skin/microbiology
MH  - Topography, Medical
MH  - Trimethoprim, Sulfamethoxazole Drug Combination/therapeutic use
MH  - Young Adult
OTO - NOTNLM
OT  - Paracoccidioides brasiliensis
OT  - Paracoccidioidomycosis
OT  - systemic mycosis
EDAT- 2014/04/05 06:00
MHDA- 2015/03/31 06:00
CRDT- 2014/04/05 06:00
PHST- 2013/09/11 00:00 [received]
PHST- 2014/01/15 00:00 [revised]
PHST- 2014/02/20 00:00 [accepted]
PHST- 2014/04/05 06:00 [entrez]
PHST- 2014/04/05 06:00 [pubmed]
PHST- 2015/03/31 06:00 [medline]
AID - 10.1111/myc.12190 [doi]
PST - ppublish
SO  - Mycoses. 2014 Sep;57(9):525-30. doi: 10.1111/myc.12190. Epub 2014 Apr 2.