PMID- 24702500 OWN - NLM STAT- MEDLINE DCOM- 20150515 LR - 20201031 IS - 1802-9973 (Electronic) IS - 0862-8408 (Linking) VI - 63 IP - 4 DP - 2014 TI - Comparison of arterial stiffness parameters in patients with coronary artery disease and diabetes mellitus using Arteriograph. PG - 429-37 AB - Recently an expert consensus document advised to standardize user procedures and a new cut-off value for carotid-femoral pulse wave velocity in daily practice. Our aim was to observe aortic pulse wave velocity (PWVao) and augmentation index (AIXao) in two high cardiovascular risk groups: patients with verified coronary artery disease (CAD) or with type 2 diabetes mellitus (T2DM). We also aimed to determine the cut-off values for PWVao, AIXao in CAD and T2DM patients using oscillometric device (Arteriograph). We investigated 186 CAD and 152 T2DM patients. PWVao and AIXao increased significantly in the CAD group compared to the age-, gender-, blood pressure-, and heart rate-matched control group (10.2+/-2.3 vs. 9.3+/-1.5 m/s; p<0.001 and 34.9+/-14.6 vs. 31.9+/-12.8 %; p<0.05, respectively). When compared to the apparently healthy control subjects, T2DM patients had significantly elevated PWVao (9.7+/-1.7 vs. 9.3+/-1.5 m/s; p<0.05, respectively), however the AIXao did not differ significantly. The ROC-curves of CAD and healthy control subjects explored cut-off values of 10.2 m/s for PWVao and 33.23 % for AIXao. Our data provide supporting evidence about impaired arterial stiffness parameters in CAD and T2DM. Our findings encourage the implementation of arterial stiffness measurements by oscillometric method in daily clinical routine. FAU - Lenkey, Z AU - Lenkey Z AD - Heart Institute, Medical School, University of Pecs, Pecs, Hungary. balazs.gaszner@aok.pte.hu. FAU - Illyes, M AU - Illyes M FAU - Bocskei, R AU - Bocskei R FAU - Husznai, R AU - Husznai R FAU - Sarszegi, Z AU - Sarszegi Z FAU - Meiszterics, Z AU - Meiszterics Z FAU - Molnar, F T AU - Molnar FT FAU - Hild, G AU - Hild G FAU - Szabados, S AU - Szabados S FAU - Cziraki, A AU - Cziraki A FAU - Gaszner, B AU - Gaszner B LA - eng PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20140403 PL - Czech Republic TA - Physiol Res JT - Physiological research JID - 9112413 SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Aging/physiology MH - Angiography/*methods MH - Blood Pressure/physiology MH - Coronary Artery Disease/drug therapy/*physiopathology MH - Diabetes Mellitus, Type 2/drug therapy/*physiopathology MH - Female MH - Heart Rate/physiology MH - Humans MH - Male MH - Middle Aged MH - Pulse Wave Analysis MH - Sex Characteristics MH - *Vascular Stiffness EDAT- 2014/04/08 06:00 MHDA- 2015/05/16 06:00 CRDT- 2014/04/08 06:00 PHST- 2014/04/08 06:00 [entrez] PHST- 2014/04/08 06:00 [pubmed] PHST- 2015/05/16 06:00 [medline] AID - 932524 [pii] AID - 10.33549/physiolres.932524 [doi] PST - ppublish SO - Physiol Res. 2014;63(4):429-37. doi: 10.33549/physiolres.932524. Epub 2014 Apr 3.