PMID- 24706048 OWN - NLM STAT- MEDLINE DCOM- 20151117 LR - 20211021 IS - 1573-2630 (Electronic) IS - 0165-5701 (Linking) VI - 35 IP - 2 DP - 2015 Apr TI - Optic nerve head drusen: a comparative study of 10 MHz and 20 MHz ultrasound probes. PG - 229-32 LID - 10.1007/s10792-014-9939-3 [doi] AB - The aim of this study was to evaluate and compare 10-MHz and 20-MHz ultrasonography in the assessment of patients with optic nerve head drusen (ONHD). The design of the study was prospective, comparative and cross-sectional. Ultrasonographic examination with a 10 and 20 MHz probe was performed in 45 eyes with suspected ONHD. The 20 MHz probe showed drusen in 43 eyes (95.5 %), while the 10 MHz probe revealed drusen in only 33 eyes (73.3 %, p = 0.0001). The 10 MHz probe showed surface drusen in 10 eyes (22.2 %), while the 20 MHz probe showed surface drusen in 14 eyes (31.1 %) (sensitivity 71.4 %; 95 % CI [47.6-95.1 %]). The 10 MHz probe showed buried drusen in 23 eyes (23.1 %), while the 20 MHz probe showed buried drusen in 29 eyes (64.4 %) (sensitivity 79.3 %; 95 % CI [56.6-86.2 %]). The sensitivity was 76.7 % with 10 MHz probe compared to a 20 MHz as gold standard. The use of 20 MHz probe increased the sensitivity of buried disc drusen by 1.5 times and surface disc drusen by nearly 2 times. Using the 10 MHz probe alone the false negative error rate was 83.3 %. The 20 MHz probe has shown itself to be an excellent method for the diagnosis of ONHD; it is more sensitive and reliable than 10 MHz probe and should be considered in the management of patients with clinical evidence of ONHD. FAU - Zaouali, Sonia AU - Zaouali S AD - Department of Ophthalmology, Fattouma Bourguiba University Hospital, Faculty of Medicine, University of Monastir, 5019, Monastir, Tunisia. FAU - Abroug, Nesrine AU - Abroug N FAU - Khochtali, Sana AU - Khochtali S FAU - Kahloun, Rim AU - Kahloun R FAU - Jelliti, Bechir AU - Jelliti B FAU - Attia, Sonia AU - Attia S FAU - Ben Yahia, Salim AU - Ben Yahia S FAU - Khairallah, Moncef AU - Khairallah M LA - eng PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20140405 PL - Netherlands TA - Int Ophthalmol JT - International ophthalmology JID - 7904294 SB - IM MH - Adolescent MH - Adult MH - Cross-Sectional Studies MH - Female MH - Humans MH - Male MH - Middle Aged MH - Optic Disk Drusen/*diagnostic imaging MH - Prospective Studies MH - Sensitivity and Specificity MH - Ultrasonography MH - Young Adult EDAT- 2014/04/08 06:00 MHDA- 2015/11/18 06:00 CRDT- 2014/04/08 06:00 PHST- 2013/10/13 00:00 [received] PHST- 2014/03/22 00:00 [accepted] PHST- 2014/04/08 06:00 [entrez] PHST- 2014/04/08 06:00 [pubmed] PHST- 2015/11/18 06:00 [medline] AID - 10.1007/s10792-014-9939-3 [doi] PST - ppublish SO - Int Ophthalmol. 2015 Apr;35(2):229-32. doi: 10.1007/s10792-014-9939-3. Epub 2014 Apr 5.