PMID- 24707093 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20140407 LR - 20211021 IS - 0915-5287 (Print) IS - 2187-5626 (Electronic) IS - 0915-5287 (Linking) VI - 26 IP - 3 DP - 2014 Mar TI - Skilled reach training influences brain recovery following intracerebral hemorrhage in rats. PG - 405-7 LID - 10.1589/jpts.26.405 [doi] AB - [Purpose] The present study investigated how skilled reach training influences functional and neurological brain recovery via a rat model with intracerebral hemorrhage. [Subjects] Thirty rats with intracerebral hemorrhage were divided into 2 groups randomly: the control group (CON) that did not receive any treatment, and the experimental group (SRT) that received skilled reach training. [Methods] The experimental group was trained through skilled reaching training with the affected upper limb in 15-minute sessions administered 6 days per week for 4 weeks. [Results] In the behavioral test, the results showed that motor function was significantly improved in the skilled reach training group compared with the control group. In the neurological teat, the expression level of brain-derived neurotrophic factor (BDNF) was significantly increased in the skilled reach training group compared with the control group. [Conclusion] Skilled reach training is able to facilitate both the expression of neurotrophic factor in the motor cortex and motor function recovery following intracerebral hemorrhage. FAU - Yong, Min-Sik AU - Yong MS AD - Department of Rehabilitation Science, Graduate School, Daegu University, Republic of Korea. FAU - Hwangbo, Kak AU - Hwangbo K AD - Department of Physical Therapy, College of Rehabilitation Science, Daegu University, Republic of Korea. LA - eng PT - Journal Article DEP - 20140325 PL - Japan TA - J Phys Ther Sci JT - Journal of physical therapy science JID - 9105359 PMC - PMC3976012 OTO - NOTNLM OT - Brain-derived neurotrophic factor OT - Intracerebral hemorrhage OT - Skilled reach training EDAT- 2014/04/08 06:00 MHDA- 2014/04/08 06:01 PMCR- 2014/03/01 CRDT- 2014/04/08 06:00 PHST- 2013/08/23 00:00 [received] PHST- 2013/10/02 00:00 [accepted] PHST- 2014/04/08 06:00 [entrez] PHST- 2014/04/08 06:00 [pubmed] PHST- 2014/04/08 06:01 [medline] PHST- 2014/03/01 00:00 [pmc-release] AID - jpts--2013-406 [pii] AID - 10.1589/jpts.26.405 [doi] PST - ppublish SO - J Phys Ther Sci. 2014 Mar;26(3):405-7. doi: 10.1589/jpts.26.405. Epub 2014 Mar 25.