PMID- 24708396
OWN - NLM
STAT- MEDLINE
DCOM- 20150721
LR  - 20181202
IS  - 1557-900X (Electronic)
IS  - 0892-7790 (Linking)
VI  - 29
IP  - 1
DP  - 2015 Jan
TI  - Percutaneous nephrolithotomy: short- and long-term effects on health-related 
      quality of life.
PG  - 13-7
LID - 10.1089/end.2014.0081 [doi]
AB  - BACKGROUND AND PURPOSE: Percutaneous nephrolithotomy (PCNL) is the treatment of 
      choice for large and complex kidney stones, having increased its safety and 
      effectiveness over the last years. Nonetheless, there is little known about its 
      impact on quality of life (QoL). This study aimed at evaluating the effects of 
      PCNL on patients' QoL in the short and long term. PATIENTS AND METHODS: We 
      prospectively studied 40 consecutive cases who underwent PCNL. QoL was measured 
      using the short form-36 (SF-36) questionnaire, 2 weeks before surgery and then in 
      the third postoperative month and a year after. Changes in QoL were assessed 
      under statistical and clinical relevance criteria. RESULTS: PCNL has rendered 70% 
      of the cases completely stone free with a 35% complication rate (33% Clavien 
      I+II). The baseline scores of all SF-36 domains were worse than the referral 
      population. Three months after PCNL, bodily pain was the only dimension whose 
      change was relevant for patients (effect size [ES]=0.71, minimal clinically 
      important difference [MCID]=0.56). A year after, this favorable effect of PCNL on 
      body pain is still present, being also beneficial on both role physical (ES=0.58, 
      MCID=0.52) and the physical component summary (ES=0.56, MCID=0.43). Social 
      function was also close to reaching clinical relevance a year after the procedure 
      (ES=0.66, MCID=0.72). CONCLUSION: Kidney stone disease considerably affects the 
      patients' QoL. PCNL not only has good outcomes rendering the kidney stone free 
      without major complications but produces an immediate body pain relief. This is 
      perceived as relevant by the patients even a year after the procedure, when some 
      other physical aspects of QoL also get better, helping patients to restore their 
      social activities.
FAU - Perez-Fentes, Daniel Adolfo
AU  - Perez-Fentes DA
AD  - 1 Department of Urology, Complejo Hospitalario Universitario de Santiago de 
      Compostela , Santiago de Compostela, Spain .
FAU - Gude, Francisco
AU  - Gude F
FAU - Blanco, Benito
AU  - Blanco B
FAU - Freire, Camilo Garcia
AU  - Freire CG
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Endourol
JT  - Journal of endourology
JID - 8807503
SB  - IM
CIN - J Endourol. 2015 Jan;29(1):17-8. PMID: 25192392
MH  - Adult
MH  - Aged
MH  - Cohort Studies
MH  - Female
MH  - *Health Status
MH  - Humans
MH  - Kidney Calculi/*surgery
MH  - Longitudinal Studies
MH  - Male
MH  - Middle Aged
MH  - Nephrostomy, Percutaneous/*methods
MH  - Prospective Studies
MH  - *Quality of Life
MH  - Surveys and Questionnaires
MH  - Time Factors
MH  - Treatment Outcome
EDAT- 2014/04/09 06:00
MHDA- 2015/07/22 06:00
CRDT- 2014/04/09 06:00
PHST- 2014/04/09 06:00 [entrez]
PHST- 2014/04/09 06:00 [pubmed]
PHST- 2015/07/22 06:00 [medline]
AID - 10.1089/end.2014.0081 [doi]
PST - ppublish
SO  - J Endourol. 2015 Jan;29(1):13-7. doi: 10.1089/end.2014.0081.