PMID- 24728579 OWN - NLM STAT- MEDLINE DCOM- 20150731 LR - 20211021 IS - 1432-2323 (Electronic) IS - 0364-2313 (Linking) VI - 38 IP - 9 DP - 2014 Sep TI - Partnership for sustainability in cardiac surgery to address critical rheumatic heart disease in sub-Saharan Africa: the experience from Rwanda. PG - 2205-11 LID - 10.1007/s00268-014-2559-2 [doi] AB - IMPORTANCE: Rheumatic heart disease (RHD) in the developing world results in critical disability among children, adolescents, and young adults-marginalizing a key population at its peak age of productivity. Few regions in sub-Saharan Africa have independently created an effective strategy to detect and treat streptococcal infection and mitigate its progression to RHD. OBJECTIVE: We describe a unique collaboration, where the Rwanda Ministry of Health, the Rwanda Heart Foundation, and an expatriate humanitarian cardiac surgery program have together leveraged an innovative partnership as a means to expand Rwanda's current capacity to address screening and primary prevention, as well as provide life-saving cardiac surgery for patients with critical RHD. EVIDENCE REVIEW: Interviews with key personnel and review of administrative records were conducted to obtain qualitative and quantitative data on the recruitment of clinical personnel, procurement of equipment, and program finances. The number of surgical cases completed and the resultant clinical outcomes are reviewed. FINDINGS: From 2008 to 2013, six annual visits were completed. A total of 128 prosthetic valves have been implanted in 86 complex patients in New York Heart Association (NYHA) class III or IV heart failure, with excellent clinical outcomes (5 % 30-day mortality). Postoperative complications included a cerebrovascular accident (n = 1) and hemorrhage, requiring reoperation (n = 2). All procedures were performed with participation of local personnel. CONCLUSIONS AND RELEVANCE: This strategy provides a reliable and consistent model of sophisticated specialty care delivery; inclusive of patient-centered cardiac surgery, mentorship, didactics, skill transfer, and investment in a sustainable cardiac program to address critical RHD in sub-Saharan Africa. FAU - Swain, JaBaris D AU - Swain JD AD - Department of Surgery, Division of Cardiac Surgery, Brigham and Women's Hospital-Harvard Medical School, Boston, MA, USA, jdswain@partners.org. FAU - Pugliese, Daniel N AU - Pugliese DN FAU - Mucumbitsi, Joseph AU - Mucumbitsi J FAU - Rusingiza, Emmanuel K AU - Rusingiza EK FAU - Ruhamya, Nathan AU - Ruhamya N FAU - Kagame, Abel AU - Kagame A FAU - Ganza, Gapira AU - Ganza G FAU - Come, Patricia C AU - Come PC FAU - Breakey, Suellen AU - Breakey S FAU - Greenwood, Bonnie AU - Greenwood B FAU - Muehlschlegel, Jochen D AU - Muehlschlegel JD FAU - Patton-Bolman, Cecilia AU - Patton-Bolman C FAU - Binagwaho, Agnes AU - Binagwaho A FAU - Morton Bolman, R AU - Morton Bolman R LA - eng GR - T32 HL007734/HL/NHLBI NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't PL - United States TA - World J Surg JT - World journal of surgery JID - 7704052 SB - IM MH - Adolescent MH - Adult MH - Capacity Building/*organization & administration MH - Delivery of Health Care/economics/*organization & administration MH - Female MH - Foundations MH - Government Agencies MH - *Heart Valve Prosthesis Implantation/adverse effects/education MH - Humans MH - Male MH - Mentors MH - Middle Aged MH - Patient Selection MH - *Program Evaluation/economics MH - Public-Private Sector Partnerships/economics/*organization & administration MH - Rheumatic Heart Disease/diagnosis/prevention & control/*surgery MH - Rwanda MH - Surgical Equipment/supply & distribution MH - Treatment Outcome MH - Workforce MH - Young Adult EDAT- 2014/04/15 06:00 MHDA- 2015/08/01 06:00 CRDT- 2014/04/15 06:00 PHST- 2014/04/15 06:00 [entrez] PHST- 2014/04/15 06:00 [pubmed] PHST- 2015/08/01 06:00 [medline] AID - 10.1007/s00268-014-2559-2 [doi] PST - ppublish SO - World J Surg. 2014 Sep;38(9):2205-11. doi: 10.1007/s00268-014-2559-2.