PMID- 24730759
OWN - NLM
STAT- MEDLINE
DCOM- 20141224
LR  - 20161125
IS  - 1478-6427 (Electronic)
IS  - 1478-6419 (Linking)
VI  - 28
IP  - 18
DP  - 2014
TI  - Hypolipidaemic and antioxidant properties of ethanol extract from Flos populi.
PG  - 1467-70
LID - 10.1080/14786419.2014.905564 [doi]
AB  - This study was undertaken to evaluate antihyperlipidaemic and in vitro 
      antioxidant activity of ethanolic extract of Flos populi (EFP). The results 
      demonstrated that EFP contains 78.5% flavonoids and 10.4% phenolics, and it 
      exhibited free radical-scavenging activity on 2,2-diphenyl-picrylhydrazyl (IC50 
      36.40 +/- 0.62 mug/mL) and high reducing power (EC50 206.32 +/- 1.6l mug/mL) under in 
      vitro chemical assays. And irrespective of prophylactic administration or 
      remedial administration, in high fat diet-induced hyperlipidaemic mice, oral 
      treatment with EFP produced a decrease in the levels of serum total cholesterol, 
      triglycerides, low-density lipoprotein-cholesterol and increase in high-density 
      lipoprotein-cholesterol. In a word, in high fat diet-fed hyperlipidaemic mice, 
      EFP (100, 200 and 400 mg/kg) significantly altered the plasma lipid levels to 
      near normal. These results support a potential effect of EFP in cardiovascular 
      disease.
FAU - Zhao, Yan
AU  - Zhao Y
AD  - a College of Chinese Medicinal Materials, Jilin Agriculture University , 
      Changchun , 130118 , Jilin , P.R. China.
FAU - Tang, Guosheng
AU  - Tang G
FAU - Cai, Enbo
AU  - Cai E
FAU - Liu, Shuangli
AU  - Liu S
FAU - Zhang, Lianxue
AU  - Zhang L
FAU - Wang, Shijie
AU  - Wang S
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140414
PL  - England
TA  - Nat Prod Res
JT  - Natural product research
JID - 101167924
RN  - 0 (Antioxidants)
RN  - 0 (Biphenyl Compounds)
RN  - 0 (Cholesterol, HDL)
RN  - 0 (Cholesterol, LDL)
RN  - 0 (Flavonoids)
RN  - 0 (Hypolipidemic Agents)
RN  - 0 (Phenols)
RN  - 0 (Picrates)
RN  - 0 (Triglycerides)
RN  - 3K9958V90M (Ethanol)
RN  - DFD3H4VGDH (1,1-diphenyl-2-picrylhydrazyl)
SB  - IM
MH  - Animals
MH  - Antioxidants/*isolation & purification/*pharmacology
MH  - Biphenyl Compounds/pharmacology
MH  - Cholesterol, HDL/blood
MH  - Cholesterol, LDL/blood
MH  - Diet, High-Fat
MH  - Ethanol
MH  - Flavonoids/*isolation & purification/pharmacology
MH  - Hypolipidemic Agents/*isolation & purification/*pharmacology
MH  - Mice
MH  - Phenols/*isolation & purification/*pharmacology
MH  - Picrates/pharmacology
MH  - Populus/*chemistry
MH  - Triglycerides/blood
OTO - NOTNLM
OT  - Flos populi
OT  - antioxidant
OT  - flavonoids
OT  - hypolipidaemic
OT  - phenols
EDAT- 2014/04/16 06:00
MHDA- 2014/12/30 06:00
CRDT- 2014/04/16 06:00
PHST- 2014/04/16 06:00 [entrez]
PHST- 2014/04/16 06:00 [pubmed]
PHST- 2014/12/30 06:00 [medline]
AID - 10.1080/14786419.2014.905564 [doi]
PST - ppublish
SO  - Nat Prod Res. 2014;28(18):1467-70. doi: 10.1080/14786419.2014.905564. Epub 2014 
      Apr 14.