PMID- 24731459
OWN - NLM
STAT- MEDLINE
DCOM- 20150209
LR  - 20140415
IS  - 0376-2491 (Print)
IS  - 0376-2491 (Linking)
VI  - 94
IP  - 3
DP  - 2014 Jan 21
TI  - [Correlation between electrocardiogram, myocardial biomarkers and left 
      ventricular dysfunction in acute anterior ST segment elevation myocardial 
      infarction].
PG  - 187-90
AB  - OBJECTIVE: To analyze the correlation between ST segment elevation, Q wave and 
      peak biomarkers with left ventricular dysfunction in patients with acute anterior 
      ST elevation myocardial infarction (STEMI). METHODS: A total of 138 consecutive 
      inpatients with acute anterior STEMI, left anterior descending branch as the 
      convict vessel, from January 2009 to January 2012 in our hospital were enrolled 
      in this study. They were divided into reperfusion (n = 92) and non-reperfusion 
      group(n = 46). Clinical data, electrocardiogram, peak biomarkers, type B 
      natriuretic peptide (BNP) were collected by physicians and the patients were 
      followed up three months. RESULTS: The sum of the ST segments elevation, Q waves 
      and Q wave leads in anterior STEMI were positive correlation with the Killip 
      grades, myocardium biomarkers, BNP and left ventricle end diastolic diameters 
      (LVEDD) [gamma, 0.52-0.75, P < 0.01], while negative correlation with left ventricle 
      ejection fraction (LVEF) [gamma, -0.63--0.95, P < 0.01]. The sum of R wave altitude 
      was negative correlation with myocardium biomarkers, BNP and LVEDD in three 
      months after the onset of STEMI [gamma, -0.48--0.79, P < 0.01], while positive 
      correlation with LVEF [gamma, 0.73-0.82, P < 0.01]. BNP, one of the best markers of 
      left heart dysfunction, was found to be strongly negative correlation with LVEF 
      in acute stage and three months after the onset of STEMI [gamma , -0.92, -0.80, P < 
      0.01]. CONCLUSION: There are close correlations between electrocardiogram, 
      myocardial biomarkers and left ventricular dysfunction in acute anterior ST 
      segment elevation myocardial infarction, which may be strong predictors for the 
      short-term prognosis.
FAU - Sun, Wang Lexian
AU  - Sun WL
AD  - Division of Cardiovascular Medicine, Affiliated Hospital of Chengde Medical 
      College, Chengde Medical College, Chengde 067000, China.
FAU - Zhao, Jie
AU  - Zhao J
AD  - Division of Cardiovascular Medicine, Affiliated Hospital of Chengde Medical 
      College, Chengde Medical College, Chengde 067000, China.
FAU - Liu, Huiling
AU  - Liu H
AD  - Division of Cardiovascular Medicine, Affiliated Hospital of Chengde Medical 
      College, Chengde Medical College, Chengde 067000, China.
FAU - Shan, Weichao
AU  - Shan W
AD  - Division of Cardiovascular Medicine, Affiliated Hospital of Chengde Medical 
      College, Chengde Medical College, Chengde 067000, China.
FAU - Zhang, Ying
AU  - Zhang Y
AD  - Division of Cardiovascular Medicine, Affiliated Hospital of Chengde Medical 
      College, Chengde Medical College, Chengde 067000, China.
FAU - Guo, Jinrui
AU  - Guo J
AD  - Division of Cardiovascular Medicine, Affiliated Hospital of Chengde Medical 
      College, Chengde Medical College, Chengde 067000, China.
FAU - Sun, Jing
AU  - Sun J
AD  - Division of Cardiovascular Medicine, Affiliated Hospital of Chengde Medical 
      College, Chengde Medical College, Chengde 067000, China.
FAU - Li, Chunhua
AU  - Li C
AD  - Division of Cardiovascular Medicine, Affiliated Hospital of Chengde Medical 
      College, Chengde Medical College, Chengde 067000, China. Email: 
      lichunhua9522@163.com.
LA  - chi
PT  - English Abstract
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Zhonghua Yi Xue Za Zhi
JT  - Zhonghua yi xue za zhi
JID - 7511141
SB  - IM
MH  - Aged
MH  - Anterior Wall Myocardial Infarction/*enzymology/*physiopathology
MH  - Electrocardiography
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myocardium/*enzymology
MH  - Prognosis
MH  - Ventricular Function, Left
EDAT- 2014/04/16 06:00
MHDA- 2015/02/11 06:00
CRDT- 2014/04/16 06:00
PHST- 2014/04/16 06:00 [entrez]
PHST- 2014/04/16 06:00 [pubmed]
PHST- 2015/02/11 06:00 [medline]
PST - ppublish
SO  - Zhonghua Yi Xue Za Zhi. 2014 Jan 21;94(3):187-90.