PMID- 24731602
OWN - NLM
STAT- MEDLINE
DCOM- 20160418
LR  - 20140613
IS  - 1532-2769 (Electronic)
IS  - 1356-689X (Linking)
VI  - 19
IP  - 4
DP  - 2014 Aug
TI  - Sensory characteristics of chronic non-specific low back pain: a subgroup 
      investigation.
PG  - 311-8
LID - S1356-689X(14)00040-X [pii]
LID - 10.1016/j.math.2014.03.006 [doi]
AB  - It has been proposed that patients with chronic non-specific low back pain 
      (CNSLBP) can be broadly classified based on clinical features that represent 
      either predominantly a mechanical pain (MP) or non-mechanical pain (NMP) profile. 
      The aim of this study was to establish if patients with CNSLBP who report 
      features of NMP demonstrate differences in pain thresholds compared to those who 
      report MP characteristics and pain-free controls. This study was a 
      cross-sectional design investigating whether pressure pain threshold (PPT) and/or 
      cold pain threshold (CPT) at three anatomical locations differed between patients 
      with mechanical CNSLBP (n = 17) versus non-mechanical CNSLBP (n = 19 and healthy 
      controls (n = 19) whilst controlling for confounders. The results of this study 
      provide evidence of increased CPT at the wrist in the NMP profile group compared 
      to both the MP profile and control subjects, when controlling for gender, sleep 
      and depression (NMP versus MP group Odds Ratio (OR): 18.4, 95% confidence 
      interval (CI): 2.5-133.1, p = 0.004). There was no evidence of lowered PPT at any 
      site after adjustment for confounding factors. Those with an MP profile had 
      similar pain thresholds to pain-free controls, whereas the NMP profile group 
      demonstrated elevated CPT's consistent with central amplification of pain. These 
      findings may represent different pain mechanisms associated with these patient 
      profiles and may have implications for targeted management.
CI  - Copyright (c) 2014 Elsevier Ltd. All rights reserved.
FAU - O'Sullivan, Peter
AU  - O'Sullivan P
AD  - School of Physiotherapy & Exercise Science, Curtin University, GPO Box 1987, 
      Perth, WA 6845, Australia. Electronic address: p.osullivan@curtin.edu.au.
FAU - Waller, Robert
AU  - Waller R
AD  - School of Physiotherapy & Exercise Science, Curtin University, GPO Box 1987, 
      Perth, WA 6845, Australia.
FAU - Wright, Anthony
AU  - Wright A
AD  - School of Physiotherapy & Exercise Science, Curtin University, GPO Box 1987, 
      Perth, WA 6845, Australia.
FAU - Gardner, Joseph
AU  - Gardner J
AD  - School of Physiotherapy & Exercise Science, Curtin University, GPO Box 1987, 
      Perth, WA 6845, Australia.
FAU - Johnston, Richard
AU  - Johnston R
AD  - School of Physiotherapy & Exercise Science, Curtin University, GPO Box 1987, 
      Perth, WA 6845, Australia.
FAU - Payne, Carly
AU  - Payne C
AD  - School of Physiotherapy & Exercise Science, Curtin University, GPO Box 1987, 
      Perth, WA 6845, Australia.
FAU - Shannon, Aedin
AU  - Shannon A
AD  - School of Physiotherapy & Exercise Science, Curtin University, GPO Box 1987, 
      Perth, WA 6845, Australia.
FAU - Ware, Brendan
AU  - Ware B
AD  - School of Physiotherapy & Exercise Science, Curtin University, GPO Box 1987, 
      Perth, WA 6845, Australia.
FAU - Smith, Anne
AU  - Smith A
AD  - School of Physiotherapy & Exercise Science, Curtin University, GPO Box 1987, 
      Perth, WA 6845, Australia.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20140325
PL  - Scotland
TA  - Man Ther
JT  - Manual therapy
JID - 9610924
SB  - IM
MH  - Adult
MH  - Age Factors
MH  - Chronic Pain/*classification/diagnosis/rehabilitation
MH  - Confidence Intervals
MH  - Cross-Sectional Studies
MH  - Female
MH  - Humans
MH  - Low Back Pain/*classification/diagnosis/rehabilitation
MH  - Male
MH  - Middle Aged
MH  - Odds Ratio
MH  - *Pain Measurement
MH  - Pain Threshold/*physiology
MH  - Reference Values
MH  - Risk Assessment
MH  - Sensory Thresholds/*physiology
MH  - Severity of Illness Index
MH  - Sex Factors
OTO - NOTNLM
OT  - Biopsychosocial
OT  - Chronic non-specific low back pain
OT  - Classification
OT  - Pain sensitivity
EDAT- 2014/04/16 06:00
MHDA- 2016/04/19 06:00
CRDT- 2014/04/16 06:00
PHST- 2013/05/22 00:00 [received]
PHST- 2014/03/06 00:00 [revised]
PHST- 2014/03/14 00:00 [accepted]
PHST- 2014/04/16 06:00 [entrez]
PHST- 2014/04/16 06:00 [pubmed]
PHST- 2016/04/19 06:00 [medline]
AID - S1356-689X(14)00040-X [pii]
AID - 10.1016/j.math.2014.03.006 [doi]
PST - ppublish
SO  - Man Ther. 2014 Aug;19(4):311-8. doi: 10.1016/j.math.2014.03.006. Epub 2014 Mar 
      25.