PMID- 24740199
OWN - NLM
STAT- MEDLINE
DCOM- 20150819
LR  - 20240210
IS  - 1538-7755 (Electronic)
IS  - 1055-9965 (Print)
IS  - 1055-9965 (Linking)
VI  - 23
IP  - 7
DP  - 2014 Jul
TI  - Variation in NF-kappaB signaling pathways and survival in invasive epithelial ovarian 
      cancer.
PG  - 1421-7
LID - 10.1158/1055-9965.EPI-13-0962 [doi]
AB  - Survival in epithelial ovarian cancer (EOC) is influenced by the host immune 
      response, yet the key genetic determinants of inflammation and immunity that 
      affect prognosis are not known. The nuclear factor-kappaB (NF-kappaB) transcription 
      factor family plays an important role in many immune and inflammatory responses, 
      including the response to cancer. We studied common inherited variation in 210 
      genes in the NF-kappaB family in 10,084 patients with invasive EOC (5,248 high-grade 
      serous, 1,452 endometrioid, 795 clear cell, and 661 mucinous) from the Ovarian 
      Cancer Association Consortium. Associations between genotype and overall survival 
      were assessed using Cox regression for all patients and by major histology, 
      adjusting for known prognostic factors and correcting for multiple testing 
      (threshold for statistical significance, P < 2.5 x 10(-5)). Results were 
      statistically significant when assessed for patients of a single histology. Key 
      associations were with caspase recruitment domain family, member 11 (CARD11) 
      rs41324349 in patients with mucinous EOC [HR, 1.82; 95% confidence interval (CI), 
      1.41-2.35; P = 4.13 x 10(-6)] and tumor necrosis factor receptor superfamily, 
      member 13B (TNFRSF13B) rs7501462 in patients with endometrioid EOC (HR, 0.68; 95% 
      CI, 0.56-0.82; P = 2.33 x 10(-5)). Other associations of note included TNF 
      receptor-associated factor 2 (TRAF2) rs17250239 in patients with high-grade 
      serous EOC (HR, 0.84; 95% CI, 0.77-0.92; P = 6.49 x 10(-5)) and phospholipase C, 
      gamma 1 (PLCG1) rs11696662 in patients with clear cell EOC (HR, 0.43; 95% CI, 
      0.26-0.73; P = 4.56 x 10(-4)). These associations highlight the potential 
      importance of genes associated with host inflammation and immunity in modulating 
      clinical outcomes in distinct EOC histologies.
CI  - (c)2014 American Association for Cancer Research.
FAU - Block, Matthew S
AU  - Block MS
AD  - Authors' Affiliations: Departments of Medical Oncology.
FAU - Charbonneau, Bridget
AU  - Charbonneau B
AD  - Health Sciences Research, Division of Epidemiology;
FAU - Vierkant, Robert A
AU  - Vierkant RA
AD  - Health Sciences Research, Division of Biomedical Statistics and Informatics;
FAU - Fogarty, Zachary
AU  - Fogarty Z
AD  - Health Sciences Research, Division of Biomedical Statistics and Informatics;
FAU - Bamlet, William R
AU  - Bamlet WR
AD  - Health Sciences Research, Division of Biomedical Statistics and Informatics;
FAU - Pharoah, Paul D P
AU  - Pharoah PD
AD  - Oncology and Public Health and Primary Care, University of Cambridge, Cambridge;
CN  - Georgia Chenevix-Trench
CN  - for AOCS
CN  - /ACS Group
FAU - Rossing, Mary Anne
AU  - Rossing MA
AD  - Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson 
      Cancer Research Center; Department of Epidemiology, University of Washington, 
      Seattle, Washington;
FAU - Cramer, Daniel
AU  - Cramer D
AD  - Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital and 
      Harvard Medical School; Department of Epidemiology, Harvard School of Public 
      Health, Boston, Massachusetts;
FAU - Pearce, Celeste Leigh
AU  - Pearce CL
AD  - Department of Preventive Medicine, Keck School of Medicine, University of 
      Southern California Norris Comprehensive Cancer Center;
FAU - Schildkraut, Joellen
AU  - Schildkraut J
AD  - Cancer Prevention, Detection, and Control Research Program, Duke Cancer 
      Institute; Department of Community and Family Medicine;
FAU - Menon, Usha
AU  - Menon U
AD  - Gynaecological Cancer Research Centre, Women's Cancer, Institute for Women's 
      Health, University College London;
FAU - Kjaer, Susanne K
AU  - Kjaer SK
AD  - The Juliane Marie Centre, Department of Obstetrics and Gynecology, 
      Rigshospitalet, Copenhagen, Denmark; Virus, Lifestyle and Genes, Danish Cancer 
      Society Research Center;
FAU - Levine, Douglas A
AU  - Levine DA
AD  - Gynecology Service, Department of Surgery;
FAU - Gronwald, Jacek
AU  - Gronwald J
AD  - Department of Genetics and Pathology, International Hereditary Cancer Center, 
      Pomeranian Medical University, Szczecin; Departments of.
FAU - Culver, Hoda Anton
AU  - Culver HA
AD  - Department of Epidemiology, Center for Cancer Genetics Research and Prevention, 
      School of Medicine, University of California Irvine, Irvine;
FAU - Whittemore, Alice S
AU  - Whittemore AS
AD  - Department of Health Research and Policy - Epidemiology, Stanford University 
      School of Medicine, Palo Alto;
FAU - Karlan, Beth Y
AU  - Karlan BY
AD  - Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute;
FAU - Lambrechts, Diether
AU  - Lambrechts D
AD  - Vesalius Research Center, VIB; Laboratory for Translational Genetics, Department 
      of Oncology, University of Leuven;
FAU - Wentzensen, Nicolas
AU  - Wentzensen N
AD  - Division of Cancer Epidemiology and Genetics, National Cancer Institute, 
      Bethesda, Maryland;
FAU - Kupryjanczyk, Jolanta
AU  - Kupryjanczyk J
AD  - Pathology and.
FAU - Chang-Claude, Jenny
AU  - Chang-Claude J
AD  - German Cancer Research Center, Division of Cancer Epidemiology, Heidelberg;
FAU - Bandera, Elisa V
AU  - Bandera EV
AD  - The Cancer Institute of New Jersey, Robert Wood Johnson Medical School, New 
      Brunswick;
FAU - Hogdall, Estrid
AU  - Hogdall E
AD  - Virus, Lifestyle and Genes, Danish Cancer Society Research Center; Molecular 
      Unit, Department of Pathology, Herlev Hospital, University of Copenhagen, 
      Copenhagen, Denmark;
FAU - Heitz, Florian
AU  - Heitz F
AD  - Department of Gynecology and Gynecologic Oncology, Dr. Horst Schmidt Kliniken 
      Wiesbaden; Department of Gynecology and Gynecologic Oncology, Kliniken 
      Essen-Mitte/Evang. Huyssens-Stiftung/Knappschaft GmbH, Essen; and.
FAU - Kaye, Stanley B
AU  - Kaye SB
AD  - Division of Clinical Studies, The Institute of Cancer Research and the Royal 
      Marsden Hospital;
FAU - Fasching, Peter A
AU  - Fasching PA
AD  - Department of Medicine, Division of Hematology and Oncology, David Geffen School 
      of Medicine, University of California at Los Angeles, Los Angeles; University 
      Hospital Erlangen, Department of Gynecology and Obstetrics, 
      Friedrich-Alexander-University Erlangen-Nuremberg, Comprehensive Cancer Center, 
      Erlangen;
FAU - Campbell, Ian
AU  - Campbell I
AD  - Research Division, Peter MacCallum Cancer Centre, Melbourne; Department of 
      Pathology, University of Melbourne, Parkville, Victoria;
FAU - Goodman, Marc T
AU  - Goodman MT
AD  - Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los 
      Angeles, California;
FAU - Pejovic, Tanja
AU  - Pejovic T
AD  - Department of Obstetrics and Gynecology; Knight Cancer Institute, Oregon Health 
      and Science University;
FAU - Bean, Yukie T
AU  - Bean YT
AD  - Department of Obstetrics and Gynecology; Knight Cancer Institute, Oregon Health 
      and Science University;
FAU - Hays, Laura E
AU  - Hays LE
AD  - Department of Hematology and Oncology and the Knight Cancer Institute, Portland, 
      Oregon;
FAU - Lurie, Galina
AU  - Lurie G
AD  - Cancer Epidemiology Program, University of Hawaii Cancer Center, Hawaii;
FAU - Eccles, Diana
AU  - Eccles D
AD  - Faculty of Medicine, University of Southampton, University Hospital Southampton;
FAU - Hein, Alexander
AU  - Hein A
AD  - University Hospital Erlangen, Department of Gynecology and Obstetrics, 
      Friedrich-Alexander-University Erlangen-Nuremberg, Comprehensive Cancer Center, 
      Erlangen;
FAU - Beckmann, Matthias W
AU  - Beckmann MW
AD  - University Hospital Erlangen, Department of Gynecology and Obstetrics, 
      Friedrich-Alexander-University Erlangen-Nuremberg, Comprehensive Cancer Center, 
      Erlangen;
FAU - Ekici, Arif B
AU  - Ekici AB
AD  - Institute of Human Genetics, Friedrich-Alexander-University Erlangen-Nuremberg, 
      Erlangen, Germany.
FAU - Paul, James
AU  - Paul J
AD  - The Beatson West of Scotland Cancer Centre, Glasgow, United Kingdom;
FAU - Brown, Robert
AU  - Brown R
AD  - Department of Surgery and Cancer, Imperial College London;
FAU - Flanagan, James M
AU  - Flanagan JM
AD  - Department of Surgery and Cancer, Imperial College London;
FAU - Harter, Philipp
AU  - Harter P
AD  - Department of Gynecology and Gynecologic Oncology, Dr. Horst Schmidt Kliniken 
      Wiesbaden; Department of Gynecology and Gynecologic Oncology, Kliniken 
      Essen-Mitte/Evang. Huyssens-Stiftung/Knappschaft GmbH, Essen; and.
FAU - du Bois, Andreas
AU  - du Bois A
AD  - Department of Gynecology and Gynecologic Oncology, Dr. Horst Schmidt Kliniken 
      Wiesbaden; Department of Gynecology and Gynecologic Oncology, Kliniken 
      Essen-Mitte/Evang. Huyssens-Stiftung/Knappschaft GmbH, Essen; and.
FAU - Schwaab, Ira
AU  - Schwaab I
AD  - Institut fur Humangenetik Wiesbaden, Wiesbaden;
FAU - Hogdall, Claus K
AU  - Hogdall CK
AD  - The Juliane Marie Centre, Department of Obstetrics and Gynecology, 
      Rigshospitalet, Copenhagen, Denmark;
FAU - Lundvall, Lene
AU  - Lundvall L
AD  - The Juliane Marie Centre, Department of Obstetrics and Gynecology, 
      Rigshospitalet, Copenhagen, Denmark;
FAU - Olson, Sara H
AU  - Olson SH
AD  - Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer 
      Center, New York, New York;
FAU - Orlow, Irene
AU  - Orlow I
AD  - Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer 
      Center, New York, New York;
FAU - Paddock, Lisa E
AU  - Paddock LE
AD  - New Jersey Department of Health, Trenton, New Jersey;
FAU - Rudolph, Anja
AU  - Rudolph A
AD  - German Cancer Research Center, Division of Cancer Epidemiology, Heidelberg;
FAU - Eilber, Ursula
AU  - Eilber U
AD  - German Cancer Research Center, Division of Cancer Epidemiology, Heidelberg;
FAU - Dansonka-Mieszkowska, Agnieszka
AU  - Dansonka-Mieszkowska A
AD  - Pathology and.
FAU - Rzepecka, Iwona K
AU  - Rzepecka IK
AD  - Pathology and.
FAU - Ziolkowska-Seta, Izabela
AU  - Ziolkowska-Seta I
AD  - Gynecologic Oncology, The Maria Sklodowska-Curie Memorial Cancer Center and 
      Institute of Oncology, Warsaw;
FAU - Brinton, Louise A
AU  - Brinton LA
AD  - Division of Cancer Epidemiology and Genetics, National Cancer Institute, 
      Bethesda, Maryland;
FAU - Yang, Hannah
AU  - Yang H
AD  - Division of Cancer Epidemiology and Genetics, National Cancer Institute, 
      Bethesda, Maryland;
FAU - Garcia-Closas, Montserrat
AU  - Garcia-Closas M
AD  - Breakthrough Breast Cancer Research Centre, London; Division of Genetics and 
      Epidemiology, Institute of Cancer Research, Sutton;
FAU - Despierre, Evelyn
AU  - Despierre E
AD  - Division of Gynecologic Oncology, Department of Obstetrics and Gynecology and 
      Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium;
FAU - Lambrechts, Sandrina
AU  - Lambrechts S
AD  - Division of Gynecologic Oncology, Department of Obstetrics and Gynecology and 
      Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium;
FAU - Vergote, Ignace
AU  - Vergote I
AD  - Division of Gynecologic Oncology, Department of Obstetrics and Gynecology and 
      Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium;
FAU - Walsh, Christine S
AU  - Walsh CS
AD  - Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute;
FAU - Lester, Jenny
AU  - Lester J
AD  - Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute;
FAU - Sieh, Weiva
AU  - Sieh W
AD  - Department of Health Research and Policy - Epidemiology, Stanford University 
      School of Medicine, Palo Alto;
FAU - McGuire, Valerie
AU  - McGuire V
AD  - Department of Health Research and Policy - Epidemiology, Stanford University 
      School of Medicine, Palo Alto;
FAU - Rothstein, Joseph H
AU  - Rothstein JH
AD  - Department of Health Research and Policy - Epidemiology, Stanford University 
      School of Medicine, Palo Alto;
FAU - Ziogas, Argyrios
AU  - Ziogas A
AD  - Department of Epidemiology, Center for Cancer Genetics Research and Prevention, 
      School of Medicine, University of California Irvine, Irvine;
FAU - Lubinski, Jan
AU  - Lubinski J
AD  - Department of Genetics and Pathology, International Hereditary Cancer Center, 
      Pomeranian Medical University, Szczecin; Departments of.
FAU - Cybulski, Cezary
AU  - Cybulski C
AD  - Department of Genetics and Pathology, International Hereditary Cancer Center, 
      Pomeranian Medical University, Szczecin; Departments of.
FAU - Menkiszak, Janusz
AU  - Menkiszak J
AD  - Clinic of Gynaecological Surgery and Oncology, Pomeranian Medical University, 
      Szczecin, Poland;
FAU - Jensen, Allan
AU  - Jensen A
AD  - Virus, Lifestyle and Genes, Danish Cancer Society Research Center;
FAU - Gayther, Simon A
AU  - Gayther SA
AD  - Department of Preventive Medicine, Keck School of Medicine, University of 
      Southern California Norris Comprehensive Cancer Center;
FAU - Ramus, Susan J
AU  - Ramus SJ
AD  - Department of Preventive Medicine, Keck School of Medicine, University of 
      Southern California Norris Comprehensive Cancer Center;
FAU - Gentry-Maharaj, Aleksandra
AU  - Gentry-Maharaj A
AD  - Gynaecological Cancer Research Centre, Women's Cancer, Institute for Women's 
      Health, University College London;
FAU - Berchuck, Andrew
AU  - Berchuck A
AD  - Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, 
      North Carolina;
FAU - Wu, Anna H
AU  - Wu AH
AD  - Department of Preventive Medicine, Keck School of Medicine, University of 
      Southern California Norris Comprehensive Cancer Center;
FAU - Pike, Malcolm C
AU  - Pike MC
AD  - Department of Preventive Medicine, Keck School of Medicine, University of 
      Southern California Norris Comprehensive Cancer Center; Department of 
      Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, 
      New York;
FAU - Van Den Berg, David
AU  - Van Den Berg D
AD  - Department of Preventive Medicine, Keck School of Medicine, University of 
      Southern California Norris Comprehensive Cancer Center;
FAU - Terry, Kathryn L
AU  - Terry KL
AD  - Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital and 
      Harvard Medical School; Department of Epidemiology, Harvard School of Public 
      Health, Boston, Massachusetts;
FAU - Vitonis, Allison F
AU  - Vitonis AF
AD  - Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital and 
      Harvard Medical School;
FAU - Ramirez, Starr M
AU  - Ramirez SM
AD  - Health Sciences Research, Division of Epidemiology;
FAU - Rider, David N
AU  - Rider DN
AD  - Health Sciences Research, Division of Biomedical Statistics and Informatics;
FAU - Knutson, Keith L
AU  - Knutson KL
AD  - Immunology; and.
FAU - Sellers, Thomas A
AU  - Sellers TA
AD  - Department of Cancer Epidemiology, Division of Population Sciences, Moffitt 
      Cancer Center, Tampa, Florida;
FAU - Phelan, Catherine M
AU  - Phelan CM
AD  - Department of Cancer Epidemiology, Division of Population Sciences, Moffitt 
      Cancer Center, Tampa, Florida;
FAU - Doherty, Jennifer A
AU  - Doherty JA
AD  - Section of Biostatistics and Epidemiology, The Geisel School of Medicine at 
      Dartmouth, Lebanon, New Hampshire;
FAU - Johnatty, Sharon E
AU  - Johnatty SE
AD  - Cancer Division, Queensland Institute of Medical Research, Herston, QLD;
FAU - deFazio, Anna
AU  - deFazio A
AD  - Department of Gynaecological Oncology, Westmead Hospital and Westmead Institute 
      for Cancer Research, University of Sydney at the Westmead Millennium Institute, 
      Westmead, Australia;
FAU - Song, Honglin
AU  - Song H
AD  - Oncology and.
FAU - Tyrer, Jonathan
AU  - Tyrer J
AD  - Oncology and.
FAU - Kalli, Kimberly R
AU  - Kalli KR
AD  - Authors' Affiliations: Departments of Medical Oncology.
FAU - Fridley, Brooke L
AU  - Fridley BL
AD  - Department of Biostatistics, University of Kansas Medical Center, Kansas City, 
      Kansas; Departments of.
FAU - Cunningham, Julie M
AU  - Cunningham JM
AD  - Laboratory Medicine and Pathology, Division of Experimental Pathology, Mayo 
      Clinic, Rochester, Minnesota;
FAU - Goode, Ellen L
AU  - Goode EL
AD  - Health Sciences Research, Division of Epidemiology; egoode@mayo.edu.
LA  - eng
GR  - 10124/CRUK_/Cancer Research UK/United Kingdom
GR  - R01-CA61107/CA/NCI NIH HHS/United States
GR  - R01-CA092044/CA/NCI NIH HHS/United States
GR  - U01 CA069417/CA/NCI NIH HHS/United States
GR  - R01 CA050385/CA/NCI NIH HHS/United States
GR  - R25 CA092049/CA/NCI NIH HHS/United States
GR  - R01-CA067262/CA/NCI NIH HHS/United States
GR  - N01 PC067010/PC/NCI NIH HHS/United States
GR  - C490/A6187/CRUK_/Cancer Research UK/United Kingdom
GR  - P01-CA017054/CA/NCI NIH HHS/United States
GR  - C536/A13086/CRUK_/Cancer Research UK/United Kingdom
GR  - P30 CA016056/CA/NCI NIH HHS/United States
GR  - R01 CA087538/CA/NCI NIH HHS/United States
GR  - R01 CA136924/CA/NCI NIH HHS/United States
GR  - K22-CA138563/CA/NCI NIH HHS/United States
GR  - R01 CA067262/CA/NCI NIH HHS/United States
GR  - R01 CA106414/CA/NCI NIH HHS/United States
GR  - P30 CA072720/CA/NCI NIH HHS/United States
GR  - C490/A10119/CRUK_/Cancer Research UK/United Kingdom
GR  - C536/A6689/CRUK_/Cancer Research UK/United Kingdom
GR  - P30 CA168524/CA/NCI NIH HHS/United States
GR  - N01-CN55424/CN/NCI NIH HHS/United States
GR  - R37-CA070867/CA/NCI NIH HHS/United States
GR  - R03-CA113148/CA/NCI NIH HHS/United States
GR  - R03 CA113148/CA/NCI NIH HHS/United States
GR  - R01 CA058598/CA/NCI NIH HHS/United States
GR  - R37 CA070867/CA/NCI NIH HHS/United States
GR  - R01-CA112523/CA/NCI NIH HHS/United States
GR  - R01-CA049449/CA/NCI NIH HHS/United States
GR  - R01-CA080742/CA/NCI NIH HHS/United States
GR  - K22 CA138563/CA/NCI NIH HHS/United States
GR  - N01-PC067010/PC/NCI NIH HHS/United States
GR  - R01 CA058860/CA/NCI NIH HHS/United States
GR  - C12292/A11174/CRUK_/Cancer Research UK/United Kingdom
GR  - P20 GM103418/GM/NIGMS NIH HHS/United States
GR  - R01 CA080742/CA/NCI NIH HHS/United States
GR  - P30-CA072720/CA/NCI NIH HHS/United States
GR  - R01-CA126841/CA/NCI NIH HHS/United States
GR  - R01-CA058598/CA/NCI NIH HHS/United States
GR  - R01 CA074850/CA/NCI NIH HHS/United States
GR  - R01-CA122443/CA/NCI NIH HHS/United States
GR  - C5047/A10692/CRUK_/Cancer Research UK/United Kingdom
GR  - N01PC35137/CA/NCI NIH HHS/United States
GR  - K07 CA092044/CA/NCI NIH HHS/United States
GR  - R01-CA087538/CA/NCI NIH HHS/United States
GR  - R01-CA014089/CA/NCI NIH HHS/United States
GR  - A10124/CRUK_/Cancer Research UK/United Kingdom
GR  - P50 CA105009/CA/NCI NIH HHS/United States
GR  - R01-CA074850/CA/NCI NIH HHS/United States
GR  - P20-GM103418/GM/NIGMS NIH HHS/United States
GR  - U19-CA148537/CA/NCI NIH HHS/United States
GR  - C490/A10124/CRUK_/Cancer Research UK/United Kingdom
GR  - C5047/A8384/CRUK_/Cancer Research UK/United Kingdom
GR  - R01 CA128978/CA/NCI NIH HHS/United States
GR  - R01-CA061132/CA/NCI NIH HHS/United States
GR  - CA115195/CA/NCI NIH HHS/United States
GR  - C1287/A 10710/CRUK_/Cancer Research UK/United Kingdom
GR  - R01-CA064277/CA/NCI NIH HHS/United States
GR  - P30 CA076292/CA/NCI NIH HHS/United States
GR  - R01 CA064277/CA/NCI NIH HHS/United States
GR  - R01-CA050385/CA/NCI NIH HHS/United States
GR  - P30 CA014089/CA/NCI NIH HHS/United States
GR  - U19 CA148537/CA/NCI NIH HHS/United States
GR  - MOP-86727/CAPMC/CIHR/Canada
GR  - P50-CA105009/CA/NCI NIH HHS/United States
GR  - R01 CA083918/CA/NCI NIH HHS/United States
GR  - U01-CA069417/CA/NCI NIH HHS/United States
GR  - R01-CA136924/CA/NCI NIH HHS/United States
GR  - P01-CA15083/CA/NCI NIH HHS/United States
GR  - R03 CA115195/CA/NCI NIH HHS/United States
GR  - U01-CA071966/CA/NCI NIH HHS/United States
GR  - R01-CA017054/CA/NCI NIH HHS/United States
GR  - R01 CA054419/CA/NCI NIH HHS/United States
GR  - R01 CA122443/CA/NCI NIH HHS/United States
GR  - 16561/CRUK_/Cancer Research UK/United Kingdom
GR  - P30 CA015083/CA/NCI NIH HHS/United States
GR  - C5047/A15007/CRUK_/Cancer Research UK/United Kingdom
GR  - R01-CA016056/CA/NCI NIH HHS/United States
GR  - R21-GM86689/GM/NIGMS NIH HHS/United States
GR  - C1312/A15589/CRUK_/Cancer Research UK/United Kingdom
GR  - R01 CA076016/CA/NCI NIH HHS/United States
GR  - R01-CA083918/CA/NCI NIH HHS/United States
GR  - K07 CA143047/CA/NCI NIH HHS/United States
GR  - K07-CA143047/CA/NCI NIH HHS/United States
GR  - R01-CA149429/CA/NCI NIH HHS/United States
GR  - CA106414/CA/NCI NIH HHS/United States
GR  - R01 CA087696/CA/NCI NIH HHS/United States
GR  - CA054419/CA/NCI NIH HHS/United States
GR  - U19 CA148112/CA/NCI NIH HHS/United States
GR  - R01 CA149429/CA/NCI NIH HHS/United States
GR  - P30-CA168524/CA/NCI NIH HHS/United States
GR  - R01-CA071766/CA/NCI NIH HHS/United States
GR  - P01 CA017054/CA/NCI NIH HHS/United States
GR  - P01-CA087696/CA/NCI NIH HHS/United States
GR  - N01 CN025403/CA/NCI NIH HHS/United States
GR  - R01-CA128978/CA/NCI NIH HHS/United States
GR  - R21 GM086689/GM/NIGMS NIH HHS/United States
GR  - R01-CA114343/CA/NCI NIH HHS/United States
GR  - R01 CA049449/CA/NCI NIH HHS/United States
GR  - R01-CA076016/CA/NCI NIH HHS/United States
GR  - U19-CA148112/CA/NCI NIH HHS/United States
GR  - R37-CA70867/CA/NCI NIH HHS/United States
GR  - K07-CA095666/CA/NCI NIH HHS/United States
GR  - R01 CA063682/CA/NCI NIH HHS/United States
GR  - R01-CA061107/CA/NCI NIH HHS/United States
GR  - P50-CA136393/CA/NCI NIH HHS/United States
GR  - K07 CA095666/CA/NCI NIH HHS/United States
GR  - C1287/A10118/CRUK_/Cancer Research UK/United Kingdom
GR  - N01-PC035137/PC/NCI NIH HHS/United States
GR  - R01 CA112523/CA/NCI NIH HHS/United States
GR  - P50 CA136393/CA/NCI NIH HHS/United States
GR  - R01 CA126841/CA/NCI NIH HHS/United States
GR  - R01 CA114343/CA/NCI NIH HHS/United States
GR  - 13086/CRUK_/Cancer Research UK/United Kingdom
GR  - R01-CA058860/CA/NCI NIH HHS/United States
GR  - R01-CA080978/CA/NCI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20140416
PL  - United States
TA  - Cancer Epidemiol Biomarkers Prev
JT  - Cancer epidemiology, biomarkers & prevention : a publication of the American 
      Association for Cancer Research, cosponsored by the American Society of 
      Preventive Oncology
JID - 9200608
RN  - 0 (NF-kappa B)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Carcinoma, Ovarian Epithelial
MH  - Female
MH  - Genotype
MH  - Humans
MH  - Middle Aged
MH  - NF-kappa B/*genetics
MH  - Neoplasm Invasiveness
MH  - Neoplasms, Glandular and Epithelial/*genetics/*mortality/pathology
MH  - Ovarian Neoplasms/*genetics/*mortality/pathology
MH  - Polymorphism, Single Nucleotide
MH  - Proportional Hazards Models
MH  - Signal Transduction/*genetics
PMC - PMC4082406
MID - EMS58136
OID - NLM: EMS58136
COIS- Conflict of interest: There are no conflicts of interest to be disclosed with the 
      exception of: Bridget Charbonneau was an employee of Mayo Clinic at the time this 
      manuscript was drafted and is currently an employee of and owns stock in Eli 
      Lilly and Company.
EDAT- 2014/04/18 06:00
MHDA- 2015/08/20 06:00
PMCR- 2015/01/01
CRDT- 2014/04/18 06:00
PHST- 2014/04/18 06:00 [entrez]
PHST- 2014/04/18 06:00 [pubmed]
PHST- 2015/08/20 06:00 [medline]
PHST- 2015/01/01 00:00 [pmc-release]
AID - 1055-9965.EPI-13-0962 [pii]
AID - 10.1158/1055-9965.EPI-13-0962 [doi]
PST - ppublish
SO  - Cancer Epidemiol Biomarkers Prev. 2014 Jul;23(7):1421-7. doi: 
      10.1158/1055-9965.EPI-13-0962. Epub 2014 Apr 16.