PMID- 24744021
OWN - NLM
STAT- MEDLINE
DCOM- 20141204
LR  - 20211021
IS  - 1534-6293 (Electronic)
IS  - 1528-4042 (Linking)
VI  - 14
IP  - 6
DP  - 2014 Jun
TI  - Resting state functional magnetic resonance imaging in Parkinson's disease.
PG  - 448
LID - 10.1007/s11910-014-0448-6 [doi]
AB  - Neuroimaging advances over the past several decades have provided increased 
      understanding of the structural and functional brain changes that occur with 
      Parkinson's disease (PD). Examination of resting state functional magnetic 
      resonance imaging (rs-fMRI) provides a noninvasive method that focuses on 
      low-frequency spontaneous fluctuations in the blood-oxygenation-level-dependent 
      signal that occurs when an individual is at rest. Several analysis methods have 
      been developed and used to explore how PD affects resting state activity and 
      functional connectivity, and the purpose of this review is to highlight the 
      critical advances made thus far. Some discrepancies in the rs-fMRI and PD 
      literature exist, and we make recommendations for consideration in future 
      studies. The rs-fMRI technique holds promise for investigating brain changes 
      associated with the motor and nonmotor symptoms of PD, and for revealing 
      important variations across large-scale networks of the brain in PD.
FAU - Prodoehl, Janey
AU  - Prodoehl J
AD  - Physical Therapy Program, Midwestern University, 555 31st Street, Downers Grove, 
      IL, USA.
FAU - Burciu, Roxana G
AU  - Burciu RG
FAU - Vaillancourt, David E
AU  - Vaillancourt DE
LA  - eng
GR  - R01 NS052318/NS/NINDS NIH HHS/United States
GR  - R01 NS075012/NS/NINDS NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - United States
TA  - Curr Neurol Neurosci Rep
JT  - Current neurology and neuroscience reports
JID - 100931790
SB  - IM
MH  - Brain/*physiopathology
MH  - Brain Mapping/methods
MH  - Humans
MH  - Magnetic Resonance Imaging/*methods
MH  - Neural Pathways/physiopathology
MH  - Parkinson Disease/*physiopathology
MH  - Rest/*physiology
EDAT- 2014/04/20 06:00
MHDA- 2014/12/15 06:00
CRDT- 2014/04/19 06:00
PHST- 2014/04/19 06:00 [entrez]
PHST- 2014/04/20 06:00 [pubmed]
PHST- 2014/12/15 06:00 [medline]
AID - 10.1007/s11910-014-0448-6 [doi]
PST - ppublish
SO  - Curr Neurol Neurosci Rep. 2014 Jun;14(6):448. doi: 10.1007/s11910-014-0448-6.