PMID- 24744959
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20140418
LR  - 20211021
IS  - 2090-8113 (Print)
IS  - 2042-0048 (Electronic)
IS  - 2042-0048 (Linking)
VI  - 2014
DP  - 2014
TI  - In Vitro Virucidal and Virustatic Properties of the Crude Extract of Cynodon 
      dactylon against Porcine Reproductive and Respiratory Syndrome Virus.
PG  - 947589
LID - 10.1155/2014/947589 [doi]
LID - 947589
AB  - The in vitro virustatic and virucidal tests of the crude extract of Cynodon 
      dactylon against infection with porcine reproductive and respiratory syndrome 
      virus (PRRSV), a cause of major devastating pig disease, were described. Crude 
      extract of C. dactylon was prepared for cytotoxicity on tissue-culture cells that 
      were used to measure virustatic and virucidal activities against PRRSV. Crude 
      extract of C. dactylon at 0.78 mg/mL showed no cytotoxicity on the cell line, and 
      at that concentration significantly inhibited replication of PRRSV as early as 24 
      hours post infection (hpi). C. dactylon also inactivated PRRSV as determined by 
      immunoperoxidase monolayer assay (IPMA) compared to the control experiments. In 
      summary, the present study may be among the earliest studies to describe 
      virustatic and virucidal activities of C. dactylon crude extract against PRRSV in 
      vitro. Extracts of C. dactylon may be useful for PRRSV control and prevention on 
      pig farms.
FAU - Pringproa, Kidsadagon
AU  - Pringproa K
AUID- ORCID: 0000-0001-7291-1100
AD  - Department of Veterinary Biosciences and Veterinary Public Health, Faculty of 
      Veterinary Medicine, Chiang Mai University, Chiang Mai 50100, Thailand.
FAU - Khonghiran, Oapkun
AU  - Khonghiran O
AD  - Department of Veterinary Biosciences and Veterinary Public Health, Faculty of 
      Veterinary Medicine, Chiang Mai University, Chiang Mai 50100, Thailand.
FAU - Kunanoppadol, Suchaya
AU  - Kunanoppadol S
AD  - Department of Veterinary Biosciences and Veterinary Public Health, Faculty of 
      Veterinary Medicine, Chiang Mai University, Chiang Mai 50100, Thailand.
FAU - Potha, Teerapong
AU  - Potha T
AD  - Central Veterinary Diagnostic Laboratory, Faculty of Veterinary Medicine, Chiang 
      Mai University, Chiang Mai 50100, Thailand.
FAU - Chuammitri, Phongsakorn
AU  - Chuammitri P
AD  - Department of Veterinary Biosciences and Veterinary Public Health, Faculty of 
      Veterinary Medicine, Chiang Mai University, Chiang Mai 50100, Thailand.
LA  - eng
PT  - Journal Article
DEP - 20140309
PL  - United States
TA  - Vet Med Int
JT  - Veterinary medicine international
JID - 101524203
PMC - PMC3972871
EDAT- 2014/04/20 06:00
MHDA- 2014/04/20 06:01
PMCR- 2014/03/09
CRDT- 2014/04/19 06:00
PHST- 2013/11/07 00:00 [received]
PHST- 2014/02/05 00:00 [revised]
PHST- 2014/02/06 00:00 [accepted]
PHST- 2014/04/19 06:00 [entrez]
PHST- 2014/04/20 06:00 [pubmed]
PHST- 2014/04/20 06:01 [medline]
PHST- 2014/03/09 00:00 [pmc-release]
AID - 10.1155/2014/947589 [doi]
PST - ppublish
SO  - Vet Med Int. 2014;2014:947589. doi: 10.1155/2014/947589. Epub 2014 Mar 9.