PMID- 24745866 OWN - NLM STAT- MEDLINE DCOM- 20141209 LR - 20140421 IS - 2093-8152 (Electronic) IS - 2005-2901 (Linking) VI - 7 IP - 2 DP - 2014 Apr TI - Direct moxibustion to treat spleen qi and yang deficiency fatigue: a pilot study. PG - 76-82 LID - S2005-2901(13)00091-5 [pii] LID - 10.1016/j.jams.2013.04.003 [doi] AB - Limited research suggests that indirect moxibustion may be beneficial for treating fatigue, but no studies to evaluate direct moxibustion have been conducted in the United States. Thus, we explored the usefulness of four outcome measures for evaluating the effectiveness of direct moxibustion for patients with spleen qi and yang deficiency fatigue (SQYDF). Eleven female volunteers, ages 25-60 years, were enrolled. Three to five rice grains in thread-sized moxa cones were burned on 11 acupuncture points once per week for 8 weeks. Eight participants completed the study. The most common adverse events (AEs) were temporary worsening of fatigue, lightheadedness, and headache. Symptomatic improvement was seen on the SF-36 energy/fatigue scale (p=0.003), SF-36 social function scale (p=0.008) and Flinders fatigue scale (p=0.014). The skin conductance at acupoints showed no consistent diagnostic baseline meridian patterns. Heart rate variability data showed an improved low frequency/high frequency (LF/HF) ratio in three of four participants. Direct moxibustion is safe in patients with SQYDF. The Flinders Fatigue Scale (FFS) and the SF-36 are useful outcome measures for evaluating the effects of direct moxibustion, and the heart rate variability (HRV) may be, but the skin conductance did not correlate with SQYDF diagnosis or with symptomatic improvement. CI - Copyright (c) 2014. Published by Elsevier B.V. FAU - Thorne, Tracy L AU - Thorne TL AD - National College of Natural Medicine, Helfgott Institute, Portland, OR, USA. Electronic address: tracy@tracythorne.net. FAU - Hanes, Doug A AU - Hanes DA AD - National College of Natural Medicine, Helfgott Institute, Portland, OR, USA. FAU - Wild, Heather AU - Wild H AD - Rentrek, Portland, OR, USA. FAU - Colbert, Agatha AU - Colbert A AD - Helfgott Research Institute, National College of Natural Medicine, Portland, OR, USA. LA - eng PT - Journal Article DEP - 20130424 PL - Korea (South) TA - J Acupunct Meridian Stud JT - Journal of acupuncture and meridian studies JID - 101490763 SB - IM MH - Adult MH - Fatigue/*therapy MH - Female MH - Galvanic Skin Response MH - Heart Rate MH - Humans MH - Middle Aged MH - Moxibustion/*methods MH - Pilot Projects MH - *Qi MH - Yang Deficiency/*therapy OTO - NOTNLM OT - Sawada OT - direct moxibustion OT - moxa OT - moxibustion OT - okyu OT - tonnetskyu EDAT- 2014/04/22 06:00 MHDA- 2014/12/15 06:00 CRDT- 2014/04/22 06:00 PHST- 2012/12/11 00:00 [received] PHST- 2013/03/12 00:00 [revised] PHST- 2013/03/21 00:00 [accepted] PHST- 2014/04/22 06:00 [entrez] PHST- 2014/04/22 06:00 [pubmed] PHST- 2014/12/15 06:00 [medline] AID - S2005-2901(13)00091-5 [pii] AID - 10.1016/j.jams.2013.04.003 [doi] PST - ppublish SO - J Acupunct Meridian Stud. 2014 Apr;7(2):76-82. doi: 10.1016/j.jams.2013.04.003. Epub 2013 Apr 24.