PMID- 24746069
OWN - NLM
STAT- MEDLINE
DCOM- 20140916
LR  - 20181202
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1343
DP  - 2014 May 23
TI  - Determination of fungicides in white grape bagasse by pressurized liquid 
      extraction and gas chromatography tandem mass spectrometry.
PG  - 18-25
LID - S0021-9673(14)00468-3 [pii]
LID - 10.1016/j.chroma.2014.03.057 [doi]
AB  - Ultrasound-assisted extraction (UAE) and pressurized liquid extraction (PLE) 
      followed by gas chromatography-triple quadrupole-mass spectrometry (GC TQ-MS) 
      were used for the rapid determination of 11 fungicides (metalaxyl, cyprodinil, 
      procymidone, iprovalicarb, myclobutanyl, kresoxim-methyl, benalaxyl, fenhexamide, 
      tebuconazole, iprodione and dimethomorph) in white grape bagasse. The extractions 
      were optimized on real non-spiked samples by means of experimental design and the 
      optimal conditions were selected to achieve the method validation. The PLE 
      procedure showed much higher efficiency than UAE for the target fungicides. Under 
      the selected extraction conditions, PLE showed satisfactory linearity, 
      repeatability and reproducibility. Recoveries for the majority of studied 
      fungicides were higher than 80% with relative standard deviations (RSD) lower 
      than 12%. Limits of detection (LODs) for GC TQ-MS were very low, at the sub 
      ngg(-1) for the majority of the target fungicides, well below the European 
      maximum residue limits (MRLs) for wine and table grapes, and vine leaves. 
      Eighteen white grape bagasse samples were analyzed and nine out of eleven targets 
      were detected in the samples. Seven of them were detected in more than 50% of the 
      samples and most samples contained at least four of the target analytes. The most 
      frequently found compounds were tebuconazole and dimethomorph with concentrations 
      between 1.6-130 and 2.0-1788ngg(-1), respectively. Some samples showed high 
      levels of many of the studied fungicides (high ngg(-1), even mugg(-1) for 
      cyprodinil, fenhexamide, iprodione and dimethomorph), but all of them below the 
      European maximum residue limits (MRLs) for wine grapes.
CI  - Copyright (c) 2014 Elsevier B.V. All rights reserved.
FAU - Celeiro, Maria
AU  - Celeiro M
AD  - Department of Analytical Chemistry, Nutrition and Food Science, Faculty of 
      Chemistry, Campus Vida, University of Santiago de Compostela, E-15782 Santiago de 
      Compostela, Spain.
FAU - Llompart, Maria
AU  - Llompart M
AD  - Department of Analytical Chemistry, Nutrition and Food Science, Faculty of 
      Chemistry, Campus Vida, University of Santiago de Compostela, E-15782 Santiago de 
      Compostela, Spain. Electronic address: maria.llompart@usc.es.
FAU - Lamas, J Pablo
AU  - Lamas JP
AD  - Department of Analytical Chemistry, Nutrition and Food Science, Faculty of 
      Chemistry, Campus Vida, University of Santiago de Compostela, E-15782 Santiago de 
      Compostela, Spain.
FAU - Lores, Marta
AU  - Lores M
AD  - Department of Analytical Chemistry, Nutrition and Food Science, Faculty of 
      Chemistry, Campus Vida, University of Santiago de Compostela, E-15782 Santiago de 
      Compostela, Spain.
FAU - Garcia-Jares, Carmen
AU  - Garcia-Jares C
AD  - Department of Analytical Chemistry, Nutrition and Food Science, Faculty of 
      Chemistry, Campus Vida, University of Santiago de Compostela, E-15782 Santiago de 
      Compostela, Spain.
FAU - Dagnac, Thierry
AU  - Dagnac T
AD  - Galician Institute for Food Quality (INGACAL), Agronomic and Agrarian Research 
      Centre (CIAM), E-15080 A Coruna, Spain.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140328
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Fungicides, Industrial)
RN  - 9004-34-6 (Cellulose)
RN  - 9006-97-7 (bagasse)
SB  - IM
MH  - Cellulose/*chemistry
MH  - Fungicides, Industrial/*analysis
MH  - Gas Chromatography-Mass Spectrometry/*methods
MH  - Limit of Detection
MH  - Reproducibility of Results
MH  - Tandem Mass Spectrometry/*methods
MH  - Vitis/*chemistry
MH  - Wine/*analysis
OTO - NOTNLM
OT  - Bagasse
OT  - Fungicides
OT  - GC-MS
OT  - GC-TQ-MS
OT  - Pressurized liquid extraction
OT  - Ultrasound-assisted extraction
EDAT- 2014/04/22 06:00
MHDA- 2014/09/17 06:00
CRDT- 2014/04/22 06:00
PHST- 2013/12/27 00:00 [received]
PHST- 2014/03/20 00:00 [revised]
PHST- 2014/03/21 00:00 [accepted]
PHST- 2014/04/22 06:00 [entrez]
PHST- 2014/04/22 06:00 [pubmed]
PHST- 2014/09/17 06:00 [medline]
AID - S0021-9673(14)00468-3 [pii]
AID - 10.1016/j.chroma.2014.03.057 [doi]
PST - ppublish
SO  - J Chromatogr A. 2014 May 23;1343:18-25. doi: 10.1016/j.chroma.2014.03.057. Epub 
      2014 Mar 28.