PMID- 24748231
OWN - NLM
STAT- MEDLINE
DCOM- 20141017
LR  - 20220311
IS  - 1573-2568 (Electronic)
IS  - 0163-2116 (Linking)
VI  - 59
IP  - 9
DP  - 2014 Sep
TI  - The use of double lasso, fully covered self-expandable metal stents with new 
      "anchoring flap" system in the treatment of benign biliary diseases.
PG  - 2308-13
LID - 10.1007/s10620-014-3158-7 [doi]
AB  - BACKGROUND: Many benign biliary diseases (BBD) can be treated with fully covered, 
      self-expandable metal stents (FCSEMS) but stent migration occurs in up to 35.7 %. 
      The aim of this study was to prospectively assess the rate of, safety and 
      effectiveness and stent migration of a new biliary FCSEMS with an anti-migration 
      flap (FCSEMS-AF) in patients with BBD. PATIENTS AND METHODS: This was a 
      prospective study from four Italian referral endoscopy centers of 32 consecutive 
      patients (10 females and 22 males; mean age: 60.1 +/- 14.8 years; range: 32-84 
      years) with BBD who were offered endoscopic placement of a FCSEMS-AF as 
      first-line therapy. RESULTS: Were 24 strictures and 8 leaks. Stent placement was 
      technically successful in 32/32 patients (100 %). Immediate clinical improvement 
      was seen in all 32 patients (100 %). One late stent migration occurred (3.3 %). 
      FCSEMS-AF were removed from 30 of the 32 patients (93.7 %) at a mean (+/- SD) of 
      124.4 +/- 84.2 days (range: 10-386 days) after placement. All patients remained 
      clinically and biochemically well at 1- and 3-month follow-up. One patient (3.3 
      %) with a post-laparoscopic cholecystectomy stricture developed distal stent 
      migration at 125 days. CONCLUSION: This new FCSEMS with anti-migration flap seems 
      to be a safe and effective first-line treatment option for patients with BBD.
FAU - Mangiavillano, B
AU  - Mangiavillano B
AD  - Gastrointestinal Endoscopy, Azienda Ospedaliera San Paolo, Universitary Hospital, 
      University of Milan, Via A. di Rudini no. 8, 20142, Milan, Italy, 
      b_mangiavillano@hotmail.com.
FAU - Manes, G
AU  - Manes G
FAU - Baron, T H
AU  - Baron TH
FAU - Frego, R
AU  - Frego R
FAU - Dinelli, M
AU  - Dinelli M
FAU - Radaelli, F
AU  - Radaelli F
FAU - Teruzzi, V
AU  - Teruzzi V
FAU - Amato, A
AU  - Amato A
FAU - Pallotta, S
AU  - Pallotta S
FAU - Santoro, T
AU  - Santoro T
FAU - Masci, E
AU  - Masci E
LA  - eng
PT  - Journal Article
DEP - 20140420
PL  - United States
TA  - Dig Dis Sci
JT  - Digestive diseases and sciences
JID - 7902782
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Anastomosis, Surgical/adverse effects
MH  - Anastomotic Leak/etiology/*therapy
MH  - Bile Duct Diseases/etiology/*therapy
MH  - Bile Ducts/*surgery
MH  - Cholangiopancreatography, Endoscopic Retrograde
MH  - Cholangitis, Sclerosing/complications
MH  - Cholecystectomy/adverse effects
MH  - Constriction, Pathologic/etiology/therapy
MH  - Device Removal
MH  - Equipment Design
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Pancreatitis, Chronic/complications
MH  - Prospective Studies
MH  - *Stents/adverse effects
MH  - Time Factors
MH  - Treatment Outcome
EDAT- 2014/04/22 06:00
MHDA- 2014/10/18 06:00
CRDT- 2014/04/22 06:00
PHST- 2014/03/13 00:00 [received]
PHST- 2014/04/05 00:00 [accepted]
PHST- 2014/04/22 06:00 [entrez]
PHST- 2014/04/22 06:00 [pubmed]
PHST- 2014/10/18 06:00 [medline]
AID - 10.1007/s10620-014-3158-7 [doi]
PST - ppublish
SO  - Dig Dis Sci. 2014 Sep;59(9):2308-13. doi: 10.1007/s10620-014-3158-7. Epub 2014 
      Apr 20.