PMID- 24748438
OWN - NLM
STAT- MEDLINE
DCOM- 20150820
LR  - 20211021
IS  - 1432-0991 (Electronic)
IS  - 0343-8651 (Linking)
VI  - 69
IP  - 3
DP  - 2014 Sep
TI  - Production and in vivo antioxidant activity of Zn, Ge, Se-enriched mycelia by 
      Cordyceps sinensis SU-01.
PG  - 270-6
LID - 10.1007/s00284-014-0582-z [doi]
AB  - Cordyceps sinensis, a traditionally edible and medicinal fungus in China, cannot 
      be artificially solid-cultured. Zinc (Zn), germanium (Ge), and selenium (Se) are 
      the essential trace elements for human body. In this work, C. sinensis SU-01 was 
      cultivated in liquid medium simultaneously containing Zn, Ge, and Se. The 
      bioactive ingredients and in vivo antioxidant activities of Zn, Ge, Se-enriched 
      mycelia (ZGSM) of C. sinensis SU-01 were investigated. Under the determined 
      conditions, the Zn, Ge, and Se contents of ZGSM were 2543.16 +/- 158.92, 1873.85 +/- 
      81.82, and 1260.16 +/- 107.12 mug/g, respectively. The optimal concentrations of Zn, 
      Ge, and Se had a positive effect on biosynthesis of protein, polysaccharide, 
      cordycepic acid, and amino acids. The activities of glutathione peroxidase 
      (GSH-Px) and superoxide dismutase (SOD) of mice blood were 3.72 +/- 0.15 and 28.74 
      +/- 2.53 % higher than that of control, respectively, and the content of 
      malondialdehyde (MDA) was 41.01 +/- 3.66 % lower than that of control.
FAU - Zheng, Lan
AU  - Zheng L
AD  - College of Life Science, Shandong Agricultural University, Taian, Shandong, 
      271018, People's Republic of China.
FAU - Hao, Long
AU  - Hao L
FAU - Ma, Hua
AU  - Ma H
FAU - Tian, Chengye
AU  - Tian C
FAU - Li, Tong
AU  - Li T
FAU - Sun, Xinyi
AU  - Sun X
FAU - Jia, Mengshi
AU  - Jia M
FAU - Jia, Le
AU  - Jia L
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140420
PL  - United States
TA  - Curr Microbiol
JT  - Current microbiology
JID - 7808448
RN  - 0 (Antioxidants)
RN  - 00072J7XWS (Germanium)
RN  - H6241UJ22B (Selenium)
RN  - J41CSQ7QDS (Zinc)
SB  - IM
MH  - Animals
MH  - Antioxidants/*analysis
MH  - Blood Chemical Analysis
MH  - Cordyceps/growth & development/*metabolism
MH  - Diet/*methods
MH  - Germanium/*metabolism
MH  - Mice
MH  - Mycelium/genetics/*metabolism
MH  - Selenium/*metabolism
MH  - Zinc/*metabolism
EDAT- 2014/04/22 06:00
MHDA- 2015/08/21 06:00
CRDT- 2014/04/22 06:00
PHST- 2013/08/01 00:00 [received]
PHST- 2014/02/26 00:00 [accepted]
PHST- 2014/04/22 06:00 [entrez]
PHST- 2014/04/22 06:00 [pubmed]
PHST- 2015/08/21 06:00 [medline]
AID - 10.1007/s00284-014-0582-z [doi]
PST - ppublish
SO  - Curr Microbiol. 2014 Sep;69(3):270-6. doi: 10.1007/s00284-014-0582-z. Epub 2014 
      Apr 20.