PMID- 24748531
OWN - NLM
STAT- MEDLINE
DCOM- 20150123
LR  - 20211021
IS  - 1439-6327 (Electronic)
IS  - 1439-6319 (Linking)
VI  - 114
IP  - 7
DP  - 2014
TI  - Co-ingestion of caffeine and carbohydrate after meal does not improve performance 
      at high-intensity intermittent sprints with short recovery times.
PG  - 1533-43
LID - 10.1007/s00421-014-2888-8 [doi]
AB  - PURPOSE: To determine the effects of co-ingesting caffeine (CAF) and carbohydrate 
      (CHO) on high-intensity intermittent sprints (HIS) performance and physiological 
      responses. METHODS: Twelve active males underwent 4 interventions at least 7 days 
      apart in a randomized, double-blind, placebo-controlled, balanced trial. A meal 
      contained 65 % CHO was provided 2 h before the HIS test. Participants ingested 
      the placebo (PLA) or CAF (6 mg kg(-1) BW) 1 h before taking an HIS test, and 
      ingested a PLA or CHO solution (0.8 g kg(-1) BW) before undergoing the testing 
      protocol. The HIS protocol comprised ten sets of 5 x 4-s sprints on a cycle 
      ergometer with a 2-min recovery between each set. RESULTS: There was no 
      significant difference between peak power output and mean power output between 
      trials (p > 0.05). Compared with PLA, CAF + CHO resulted in a 5.2 % reduction in 
      total work, corresponding to a 24.7-25.7 % increase in fatigue at the end stage 
      of the HIS. The administration of CAF + CHO supplementation also resulted in an 
      11.1 % increase in blood lactate, and elevated blood glucose concentrations 
      throughout HIS testing compared with PLA (p < 0.05). Cortisol concentrations also 
      increased with CAF + CHO intake compared with PLA; however, there was no 
      significant effect of CAF + CHO supplementation on testosterone concentrations. 
      CONCLUSION: Co-ingestion of CAF and CHO did not improve high-intensity sprint 
      cycling performance or reduce fatigue in active males. Moreover, combined CAF and 
      CHO supplementation might facilitate catabolism during prolonged high-intensity 
      intermittent exercise.
FAU - Lee, Chia-Lun
AU  - Lee CL
AD  - Physical Education Section of General Education, National Sun Yat-sen University, 
      Kaohsiung, Taiwan, karenlee1129@gmail.com.
FAU - Cheng, Ching-Feng
AU  - Cheng CF
FAU - Lee, Chia-Jung
AU  - Lee CJ
FAU - Kuo, Yu-Hsuan
AU  - Kuo YH
FAU - Chang, Wen-Dien
AU  - Chang WD
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20140420
PL  - Germany
TA  - Eur J Appl Physiol
JT  - European journal of applied physiology
JID - 100954790
RN  - 0 (Biomarkers)
RN  - 0 (Blood Glucose)
RN  - 0 (Central Nervous System Stimulants)
RN  - 0 (Dietary Carbohydrates)
RN  - 33X04XA5AT (Lactic Acid)
RN  - 3G6A5W338E (Caffeine)
RN  - 3XMK78S47O (Testosterone)
RN  - WI4X0X7BPJ (Hydrocortisone)
SB  - IM
MH  - Bicycling
MH  - Biomarkers/blood
MH  - Blood Glucose/drug effects/metabolism
MH  - Caffeine/*administration & dosage
MH  - Central Nervous System Stimulants/*administration & dosage
MH  - Dietary Carbohydrates/*administration & dosage
MH  - Double-Blind Method
MH  - Exercise Test
MH  - Humans
MH  - Hydrocortisone/blood
MH  - Lactic Acid/blood
MH  - Male
MH  - Muscle Contraction/drug effects
MH  - Muscle Fatigue
MH  - Muscle, Skeletal/*drug effects/metabolism
MH  - Physical Endurance/*drug effects
MH  - Recovery of Function
MH  - Taiwan
MH  - Testosterone/blood
MH  - Time Factors
MH  - Young Adult
EDAT- 2014/04/22 06:00
MHDA- 2015/01/24 06:00
CRDT- 2014/04/22 06:00
PHST- 2013/11/12 00:00 [received]
PHST- 2014/04/03 00:00 [accepted]
PHST- 2014/04/22 06:00 [entrez]
PHST- 2014/04/22 06:00 [pubmed]
PHST- 2015/01/24 06:00 [medline]
AID - 10.1007/s00421-014-2888-8 [doi]
PST - ppublish
SO  - Eur J Appl Physiol. 2014;114(7):1533-43. doi: 10.1007/s00421-014-2888-8. Epub 
      2014 Apr 20.