PMID- 24749733
OWN - NLM
STAT- MEDLINE
DCOM- 20150710
LR  - 20141113
IS  - 1460-2202 (Electronic)
IS  - 0271-3683 (Linking)
VI  - 39
IP  - 12
DP  - 2014 Dec
TI  - The effect of fractal contact lenses on peripheral refraction in myopic model 
      eyes.
PG  - 1151-60
LID - 10.3109/02713683.2014.903498 [doi]
AB  - PURPOSE: To test multizone contact lenses in model eyes: Fractal Contact Lenses 
      (FCLs), designed to induce myopic peripheral refractive error (PRE). METHODS: 
      Zemax ray-tracing software was employed to simulate myopic and 
      accommodation-dependent model eyes fitted with FCLs. PRE, defined in terms of 
      mean sphere M and 90 degrees -180 degrees  astigmatism J180, was computed at different peripheral 
      positions, ranging from 0 to 35 degrees  in steps of 5 degrees , and for different pupil 
      diameters (PDs). Simulated visual performance and changes in the PRE were also 
      analyzed for contact lens decentration and model eye accommodation. For 
      comparison purposes, the same simulations were performed with another 
      commercially available contact lens designed for the same intended use: the Dual 
      Focus (DF). RESULTS: PRE was greater with FCL than with DF when both designs were 
      tested for a 3.5 mm PD, and with and without decentration of the lenses. However, 
      PRE depended on PD with both multizone lenses, with a remarkable reduction of the 
      myopic relative effect for a PD of 5.5 mm. The myopic PRE with contact lenses 
      decreased as the myopic refractive error increased, but this could be compensated 
      by increasing the power of treatment zones. A peripheral myopic shift was also 
      induced by the FCLs in the accommodated model eye. In regard to visual 
      performance, a myopia under-correction with reference to the circle of least 
      confusion was obtained in all cases for a 5.5 mm PD. The ghost images, generated 
      by treatment zones of FCL, were dimmer than the ones produced with DF lens of the 
      same power. CONCLUSIONS: FCLs produce a peripheral myopic defocus without 
      compromising central vision in photopic conditions. FCLs have several design 
      parameters that can be varied to obtain optimum results: lens diameter, number of 
      zones, addition and asphericity; resulting in a very promising customized lens 
      for the treatment of myopia progression.
FAU - Rodriguez-Vallejo, Manuel
AU  - Rodriguez-Vallejo M
AD  - Centro de Tecnologias Fisicas, Universitat Politecnica de Valencia , Valencia , 
      Spain and.
FAU - Benlloch, Josefa
AU  - Benlloch J
FAU - Pons, Amparo
AU  - Pons A
FAU - Monsoriu, Juan A
AU  - Monsoriu JA
FAU - Furlan, Walter D
AU  - Furlan WD
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140421
PL  - England
TA  - Curr Eye Res
JT  - Current eye research
JID - 8104312
SB  - IM
MH  - Accommodation, Ocular/physiology
MH  - *Contact Lenses, Hydrophilic
MH  - *Fractals
MH  - Humans
MH  - *Models, Biological
MH  - Myopia/physiopathology/*therapy
MH  - Prosthesis Design
MH  - Refraction, Ocular/*physiology
MH  - Visual Fields/physiology
OTO - NOTNLM
OT  - Contact lenses
OT  - model eyes
OT  - myopia
OT  - myopia progression
OT  - peripheral refraction
EDAT- 2014/04/23 06:00
MHDA- 2015/07/15 06:00
CRDT- 2014/04/23 06:00
PHST- 2014/04/23 06:00 [entrez]
PHST- 2014/04/23 06:00 [pubmed]
PHST- 2015/07/15 06:00 [medline]
AID - 10.3109/02713683.2014.903498 [doi]
PST - ppublish
SO  - Curr Eye Res. 2014 Dec;39(12):1151-60. doi: 10.3109/02713683.2014.903498. Epub 
      2014 Apr 21.