PMID- 24759290 OWN - NLM STAT- MEDLINE DCOM- 20141021 LR - 20180508 IS - 1537-2677 (Electronic) IS - 0740-9303 (Linking) VI - 30 IP - 3 DP - 2014 May-Jun TI - Transcranial orbital decompression for progressive compressive optic neuropathy after 3-wall decompression in severe graves' orbitopathy. PG - 215-8 LID - 10.1097/IOP.0000000000000052 [doi] AB - PURPOSE: To determine surgical outcomes after transcranial decompression of the superior orbit in patients with progressive compressive optic neuropathy (CON) secondary to Graves' orbitopathy (GO) who had previously been treated with 3-wall decompression. METHODS: Approval from the West Virginia University Institution Review Board was obtained. A retrospective review of 4 patients with GO who received bilateral transcranial decompression of the orbits for progressive compressive optic neuropathy after bilateral maximal extracranial 3-wall decompression was performed. The patients were treated by the Multidisciplinary Orbit and Skull Base Services at West Virginia University and the University of Michigan. RESULTS: Bilateral transcranial decompression of the orbit for GO was performed on 8 orbits in 4 patients. All 8 orbits had radiographic evidence of compression of the orbital apex, and all patients had been treated with steroids, orbital radiation, and bilateral 3-wall decompression. Preoperative vision ranged from 20/25 to 20/100, which improved to 20/25 or better in all eyes. The visual field mean deviation improved from a mean of -13.05 to -1.67 dB. Hertel measurements improved from a mean of 19.25 to 15.25 mm. Extraocular motility was essentially unchanged. Two patients were noted to have asymptomatic ocular pulsations. There were no other complications, and all patients remained stable during a follow-up period of 5 years (range 2-8 years). CONCLUSIONS: Transcranial decompression is an effective and safe method of salvaging vision when standard treatments fail. This is only the second report of transcranial decompression for refractory compressive optic neuropathy after decompression from a standard approach. FAU - Bingham, Chad M AU - Bingham CM AD - *Department of Ophthalmology, West Virginia University Eye Institute; daggerDepartment of Neurosurgery, West Virginia University, Morgantown, West Virginia; double daggerDepartment of Otolaryngology, and section signDepartment of Ophthalmology, Kellogg Eye Center, University of Michigan, Ann Arbor, Michigan, U.S.A. FAU - Harris, Matheson A AU - Harris MA FAU - Vidor, Ira A AU - Vidor IA FAU - Rosen, Charles L AU - Rosen CL FAU - Linberg, John V AU - Linberg JV FAU - Marentette, Lawrence J AU - Marentette LJ FAU - Elner, Victor M AU - Elner VM FAU - Sivak-Callcott, Jennifer A AU - Sivak-Callcott JA LA - eng PT - Case Reports PT - Journal Article PL - United States TA - Ophthalmic Plast Reconstr Surg JT - Ophthalmic plastic and reconstructive surgery JID - 8508431 SB - IM MH - Aged MH - Decompression, Surgical/*methods MH - Female MH - Graves Ophthalmopathy/*surgery MH - Humans MH - Male MH - Middle Aged MH - Nerve Compression Syndromes/etiology/*surgery MH - Optic Nerve Diseases/etiology/*surgery MH - Orbit/*surgery MH - Orbital Diseases/*surgery MH - *Postoperative Complications MH - Treatment Outcome MH - Visual Acuity/physiology MH - Visual Fields/physiology EDAT- 2014/04/25 06:00 MHDA- 2014/10/22 06:00 CRDT- 2014/04/25 06:00 PHST- 2014/04/25 06:00 [entrez] PHST- 2014/04/25 06:00 [pubmed] PHST- 2014/10/22 06:00 [medline] AID - 10.1097/IOP.0000000000000052 [doi] PST - ppublish SO - Ophthalmic Plast Reconstr Surg. 2014 May-Jun;30(3):215-8. doi: 10.1097/IOP.0000000000000052.