PMID- 24761427
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240322
IS  - 2306-9317 (Print)
IS  - 2306-9317 (Electronic)
IS  - 2306-9317 (Linking)
VI  - 1
IP  - 1
DP  - 2012 Dec 1
TI  - Material Mismatch Effect on the Fracture of a Bone-Composite Cement Interface.
PG  - 1-8
AB  - The interfacial mechanics at the bone-implant interface is a critical issue for 
      implant fixation and the filling of bone defects created by tumors and/or their 
      excision. Our previous study found that micron and nano sizes MgO particles 
      improved the fracture toughness of bone-cement interfaces under tension loading. 
      The strength of bonding of different types of bone with different types of 
      implants may not be the same. The aims of this research were to determine the 
      influences of material mismatch due to bone orientation and a magnesium oxide 
      (MgO) filler material for PMMA bone cement on the mechanical strength between 
      bone and bone cement specimens. This research studied the longitudinal and 
      transverse directions bovine cortical bone as different bone materials and poly 
      Methyl MethAcrylate (PMMA) bone cement with and without MgO additives as 
      different implant materials. The scope of work for this study was: (1) to 
      determine the bending strength and modulus of different bone and bone cement 
      specimens, (2) to determine whether inclusion of MgO particles on PMMA has any 
      influence on these mechanical properties of PMMA, and (3) to determine whether 
      bone orientation and inclusion of MgO particles with PMMA has any influence on 
      the interface strength between bone and PMMA. This study showed that bone 
      orientation has statistically significant effect on the bonding strength between 
      bone and bone cement specimens (P value<0.05). This study also found that while 
      MgO additive decreased the bending strength and modulus of PMMA bone cement, but 
      the inclusion of MgO additives with PMMA bone cement has no statistically 
      significant effect on the bonding strength between bone and bone cement specimens 
      (P value>0.05).
FAU - Khandaker, M
AU  - Khandaker M
AD  - Department of Engineering and Physics, University of Central Oklahoma, Edmond, 
      Oklahoma.
FAU - Tarantini, S
AU  - Tarantini S
AD  - Department of Engineering and Physics, University of Central Oklahoma, Edmond, 
      Oklahoma.
LA  - eng
GR  - P20 GM103447/GM/NIGMS NIH HHS/United States
GR  - P20 RR016478/RR/NCRR NIH HHS/United States
PT  - Journal Article
PL  - China (Republic : 1949- )
TA  - Adv Mater Sci Appl
JT  - Advances in materials science and applications
JID - 101601640
PMC - PMC3992523
MID - NIHMS435028
OTO - NOTNLM
OT  - Additives
OT  - Cortical Bone
OT  - Mechanical Properties
OT  - Mgo
OT  - PMMA
EDAT- 2012/12/01 00:00
MHDA- 2012/12/01 00:01
PMCR- 2014/04/21
CRDT- 2014/04/25 06:00
PHST- 2014/04/25 06:00 [entrez]
PHST- 2012/12/01 00:00 [pubmed]
PHST- 2012/12/01 00:01 [medline]
PHST- 2014/04/21 00:00 [pmc-release]
AID - 10.5963/AMSA0101001 [doi]
PST - ppublish
SO  - Adv Mater Sci Appl. 2012 Dec 1;1(1):1-8. doi: 10.5963/AMSA0101001.