PMID- 24761917
OWN - NLM
STAT- MEDLINE
DCOM- 20150107
LR  - 20190606
IS  - 2476-762X (Electronic)
IS  - 1513-7368 (Linking)
VI  - 15
IP  - 6
DP  - 2014
TI  - Underutilization of curative treatment among patients with non small cell lung 
      cancer: experience from a tertiary care centre in India.
PG  - 2875-8
AB  - BACKGROUND: Lung cancer is one of the commonest and most lethal cancers 
      throughout the world. The majority of the patients present at advance stage and 
      are not suitable for curative intent treatment. Even among patients with 
      localized disease, there has been underutilization of curative treatment 
      modalities. The aim of this study was to analyze the radical treatment 
      utilization rates in patients with non small cell lung cancer (NSCLC) treated at 
      our centre. MATERIALS AND METHODS: We analyzed case records of 104 patients with 
      a pathologically confirmed diagnosis of NSCLC having stage 1-3B disease who were 
      treated at our centre over last 3 years, to assess the utilization of curative 
      treatment modalities i.e. surgery or radical radiotherapy. RESULTS: The median 
      age of this cohort was 58 years. Out of 104 patients only 33 (31.7%) received 
      curative intent treatment, 14 undergoing curative resection and 19 receiving 
      radical doses of radiotherapy. The baseline characteristics of both the groups 
      (with or without radical treatment) were not different. Major factors associated 
      with underutilization with curative treatment were progressive disease or loss of 
      follow up after chemotherapy and inappropriate use of TKI and/ or palliative 
      radiotherapy in patients with stage 1-3B disease. Patients who did not receive 
      radical treatment had inferior PFS and OS than those who received radical 
      treatment. CONCLUSIONS: In our practice we observed gross underutilization of 
      curative intent treatment modalities in patients with NSCLCs which is associated 
      with inferior survival.
FAU - Malik, Prabhat Singh
AU  - Malik PS
AD  - Departments of Medical Oncology, Dr. B.R.A. Institute Rotary Cancer Hospital, All 
      India Institute of Medical Sciences, New Delhi, India E-mail : 
      drprabhatsm@gmail.com.
FAU - Malik, Anita
AU  - Malik A
FAU - Deo, Suryanarayana Venkata
AU  - Deo SV
FAU - Mohan, Anant
AU  - Mohan A
FAU - Mohanti, Bidhu Kalyan
AU  - Mohanti BK
FAU - Raina, Vinod
AU  - Raina V
LA  - eng
PT  - Journal Article
PL  - Thailand
TA  - Asian Pac J Cancer Prev
JT  - Asian Pacific journal of cancer prevention : APJCP
JID - 101130625
SB  - IM
MH  - Adenocarcinoma/mortality/pathology/therapy
MH  - Adult
MH  - Aged
MH  - Carcinoma, Large Cell/mortality/pathology/therapy
MH  - Carcinoma, Non-Small-Cell Lung/mortality/pathology/*therapy
MH  - Carcinoma, Squamous Cell/mortality/pathology/therapy
MH  - Combined Modality Therapy/*statistics & numerical data
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - India
MH  - Lung Neoplasms/mortality/pathology/therapy
MH  - Male
MH  - Middle Aged
MH  - Neoplasm Staging
MH  - *Patient Compliance
MH  - *Practice Patterns, Physicians'
MH  - Prognosis
MH  - Survival Rate
MH  - Tertiary Care Centers
EDAT- 2014/04/26 06:00
MHDA- 2015/01/08 06:00
CRDT- 2014/04/26 06:00
PHST- 2014/04/26 06:00 [entrez]
PHST- 2014/04/26 06:00 [pubmed]
PHST- 2015/01/08 06:00 [medline]
AID - 10.7314/apjcp.2014.15.6.2875 [doi]
PST - ppublish
SO  - Asian Pac J Cancer Prev. 2014;15(6):2875-8. doi: 10.7314/apjcp.2014.15.6.2875.