PMID- 24771010
OWN - NLM
STAT- MEDLINE
DCOM- 20150115
LR  - 20221207
IS  - 1439-3646 (Electronic)
IS  - 0947-7349 (Linking)
VI  - 122
IP  - 4
DP  - 2014 Apr
TI  - The relationship between acute coronary syndrome and stress hyperglycemia.
PG  - 222-6
LID - 10.1055/s-0034-1367002 [doi]
AB  - BACKGROUND AND OBJECTIVE: Hyperglycemia on admission is associated with increased 
      mortality and morbidity in acute coronary syndrome (ACS) irrespective of presence 
      of diabetes mellitus. To the best of our knowledge, no evidence on the 
      relationship between stress hyperglycemia (SH) and the extent of coronary artery 
      disease is found in the literature. Our objective in this study is to assess the 
      relationship of SH with the prognosis of acute coronary syndrome, extent of 
      coronary artery disease (CAD), development of arrhythmia, and major adverse 
      cardiac events. METHOD: 89 patients who were hospitalized in the coronary 
      intensive care unit with diagnosis of ACS between January 2010 and June 2010 were 
      enrolled in the study. The patients were separated into 2 groups as having stress 
      hypergly-cemia or not, according to their blood glucose levels on admission. TIMI 
      and GRACE risk scores were obtained and GENSINI scoring was performed to assess 
      CAD extent for all the patients. Major adverse cardiac events (MACE) (death, MI, 
      re-revascularization, stroke) were recorded for all patients while in the 
      hospital and at 1st and 6th months. RESULTS: In our study, MACE, GENSINI scores 
      at 6 months and development of in-hospital arrhythmia rates were statistically 
      significantly higher and left ventricular ejection fractions were statistically 
      significantly lower in the group with SH. The association of TIMI, GRACE, 
      GENSINI, New York Heart Association (NYHA) and Killip classifications with blood 
      glucose, fasting blood glucose and HbA1c on admission was confirmed. CONCLUSION: 
      Prognostic course happens to be worse and CAD is more extensive in patients with 
      SH. In addition, blood glucose values may have to be estimated lower compared to 
      the samples in the literature, in order to diagnose SH.
CI  - (c) J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart . New York.
FAU - Ayhan, H
AU  - Ayhan H
AD  - Department of Cardiology, Faculty of Medicine, Yildirim Beyazit University.
FAU - Durmaz, T
AU  - Durmaz T
AD  - Department of Cardiology, Faculty of Medicine, Yildirim Beyazit University.
FAU - Keles, T
AU  - Keles T
AD  - Department of Cardiology, Faculty of Medicine, Yildirim Beyazit University.
FAU - Bayram, N A
AU  - Bayram NA
AD  - Department of Cardiology, Ankara Ataturk Education and Research Hospital.
FAU - Bilen, E
AU  - Bilen E
AD  - Department of Cardiology, Ankara Ataturk Education and Research Hospital.
FAU - Akcay, M
AU  - Akcay M
AD  - Department of Cardiology, Faculty of Medicine, Yildirim Beyazit University.
FAU - Ersoy, R
AU  - Ersoy R
AD  - Department of Endocrinology, Ankara Ataturk Education and Research Hospital.
FAU - Bozkurt, E
AU  - Bozkurt E
AD  - Department of Cardiology, Faculty of Medicine, Yildirim Beyazit University.
LA  - eng
PT  - Journal Article
DEP - 20140425
PL  - Germany
TA  - Exp Clin Endocrinol Diabetes
JT  - Experimental and clinical endocrinology & diabetes : official journal, German 
      Society of Endocrinology [and] German Diabetes Association
JID - 9505926
RN  - 0 (Blood Glucose)
RN  - 0 (Glycated Hemoglobin A)
RN  - 0 (Troponin I)
RN  - 9007-41-4 (C-Reactive Protein)
RN  - EC 2.7.3.2 (Creatine Kinase)
SB  - IM
MH  - Acute Coronary Syndrome/blood/*complications
MH  - Aged
MH  - Blood Glucose/metabolism
MH  - C-Reactive Protein/metabolism
MH  - Creatine Kinase/blood
MH  - Female
MH  - Glycated Hemoglobin/analysis
MH  - Humans
MH  - Hyperglycemia/blood/*complications
MH  - Male
MH  - Middle Aged
MH  - Prospective Studies
MH  - Statistics, Nonparametric
MH  - Stress, Physiological/*physiology
MH  - Troponin I/blood
EDAT- 2014/04/29 06:00
MHDA- 2015/01/16 06:00
CRDT- 2014/04/29 06:00
PHST- 2014/04/29 06:00 [entrez]
PHST- 2014/04/29 06:00 [pubmed]
PHST- 2015/01/16 06:00 [medline]
AID - 10.1055/s-0034-1367002 [doi]
PST - ppublish
SO  - Exp Clin Endocrinol Diabetes. 2014 Apr;122(4):222-6. doi: 10.1055/s-0034-1367002. 
      Epub 2014 Apr 25.