PMID- 24772398
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20140624
LR  - 20220408
IS  - 2251-8363 (Print)
IS  - 2251-8819 (Electronic)
IS  - 2251-8363 (Linking)
VI  - 3
IP  - 2
DP  - 2014
TI  - Dengue-associated kidney disease.
PG  - 57-62
LID - 10.12860/jnp.2014.13 [doi]
AB  - CONTEXT: A mosquito-borne viral illness highly prevalent in the tropics and 
      subtropics, dengue is considered a major global health threat by the World Health 
      Organization. EVIDENCE ACQUISITIONS: Directory of Open Access Journals (DOAJ), 
      Google Scholar, PubMed (NLM), LISTA (EBSCO) and Web of Science have been 
      searched. RESULTS: An RNA virus from the genus Flavivirus, dengue virus is 
      transmitted by Aedes aegypti,the yellow fever mosquito. Dengue is asymptomatic in 
      as many as one half of infected individuals. Dengue fever is an acute febrile 
      illness accompanied by constitutional symptoms. Dengue hemorrhagic fever and 
      dengue shock syndrome are the severe forms of dengue infection.Dengue infection 
      has been associated with a variety of renal disorders. Acute renal failure is a 
      potential complication of severe dengue infection and is typically associated 
      with hypotension, rhabdomyolysis, or hemolysis. Acute renal failure complicates 
      severe dengue infection in 2-5% of the cases and carries a high mortality rate. 
      Proteinuria has been detected in as high as 74% of patients with severe dengue 
      infection. Hematuria has been reported in up to 12.5% of patients. Various types 
      of glomerulonephritis have been reported during or shortly after dengue infection 
      in humans and mouse models of dengue infection. Mesangial proliferation and 
      immune complex deposition are the dominant histologic features of 
      dengue-associated glomerulonephritis. On a rare occasion, dengue infection is 
      associated with systemic autoimmune disorders involving the kidneys. CONCLUSIONS: 
      In the vast majority of cases, dengue infection and associated renal disorders 
      are self-limited.
FAU - Lizarraga, Karlo J
AU  - Lizarraga KJ
AD  - Department of Medicine, University of Miami, USA.
FAU - Nayer, Ali
AU  - Nayer A
AD  - Division of Nephrology and Hypertension, University of Miami, USA.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20131228
PL  - Iran
TA  - J Nephropathol
JT  - Journal of nephropathology
JID - 101611182
PMC - PMC3999585
OTO - NOTNLM
OT  - Acute renal failure
OT  - Dengue infection
OT  - Glomerulonephritis
OT  - Hematuria
OT  - Proteinuria
EDAT- 2014/04/29 06:00
MHDA- 2014/04/29 06:01
PMCR- 2014/01/01
CRDT- 2014/04/29 06:00
PHST- 2013/08/10 00:00 [received]
PHST- 2013/11/29 00:00 [accepted]
PHST- 2014/04/29 06:00 [entrez]
PHST- 2014/04/29 06:00 [pubmed]
PHST- 2014/04/29 06:01 [medline]
PHST- 2014/01/01 00:00 [pmc-release]
AID - 10.12860/jnp.2014.13 [doi]
PST - ppublish
SO  - J Nephropathol. 2014;3(2):57-62. doi: 10.12860/jnp.2014.13. Epub 2013 Dec 28.