PMID- 24772959
OWN - NLM
STAT- MEDLINE
DCOM- 20140710
LR  - 20140429
IS  - 0301-1208 (Print)
IS  - 0301-1208 (Linking)
VI  - 50
IP  - 5
DP  - 2013 Oct
TI  - Inflammation and MMPs in alcohol-induced liver diseases and protective action of 
      antioxidants.
PG  - 377-86
AB  - The consumption of alcohol causes several liver-associated diseases all over the 
      world. Alcoholic liver diseases (ALD) include hepatic inflammation, fatty liver, 
      hepatitis, liver cirrhosis and fibrosis and finally hepatocellular carcinoma. 
      Although the cellular, metabolic and biochemical mechanisms for these diseases 
      are quite explicable, the roles of matrix metalloproteinases (MMPs) and tissue 
      inhibitors of MMPs (TIMPs) are still under investigation. The present review 
      describes the roles and regulation of MMPs and TIMPs in different ALDs along with 
      the involvement of other pathways. This review also summarizes the present 
      knowledge on clinical and experimental trials with different antioxidants that 
      help against alcohol associated liver diseases.
FAU - Banerjee, Pamela
AU  - Banerjee P
FAU - Jana, Sayantan
AU  - Jana S
FAU - Chakraborty, Somsuta
AU  - Chakraborty S
FAU - Swarnakar, Snehasikta
AU  - Swarnakar S
LA  - eng
PT  - Journal Article
PT  - Review
PL  - India
TA  - Indian J Biochem Biophys
JT  - Indian journal of biochemistry & biophysics
JID - 0310774
RN  - 0 (Antioxidants)
RN  - EC 3.4.24.- (Matrix Metalloproteinases)
SB  - IM
MH  - Antioxidants/*pharmacology
MH  - Cytoprotection/drug effects
MH  - Inflammation/complications
MH  - Liver Diseases, Alcoholic/complications/*enzymology/pathology/*prevention & 
      control
MH  - Matrix Metalloproteinases/*metabolism
EDAT- 2014/04/30 06:00
MHDA- 2014/07/11 06:00
CRDT- 2014/04/30 06:00
PHST- 2014/04/30 06:00 [entrez]
PHST- 2014/04/30 06:00 [pubmed]
PHST- 2014/07/11 06:00 [medline]
PST - ppublish
SO  - Indian J Biochem Biophys. 2013 Oct;50(5):377-86.