PMID- 24773097
OWN - NLM
STAT- MEDLINE
DCOM- 20150223
LR  - 20181202
IS  - 1941-837X (Electronic)
IS  - 1369-6998 (Linking)
VI  - 17
IP  - 7
DP  - 2014 Jul
TI  - Incremental costs associated with myocardial infarction and stroke in patients 
      with type 2 diabetes mellitus: an overview for economic modeling.
PG  - 469-80
LID - 10.3111/13696998.2014.915847 [doi]
AB  - OBJECTIVE: To identify cost estimates related to myocardial infarction (MI) or 
      stroke in patients with type 2 diabetes mellitus (T2DM) for use in economic 
      models. METHODS: A systematic literature review was conducted. Electronic 
      databases and conference abstracts were screened against inclusion criteria, 
      which included studies performed in patients who had T2DM before experiencing an 
      MI or stroke. Primary cost studies and economic models were included. Costs were 
      converted to 2012 pounds sterling. RESULTS: Fifty-four studies were identified: 
      13 primary cost studies and 41 economic evaluations using secondary sources for 
      complication costs. Primary studies provided costs from 10 countries. Estimates 
      for a fatal event ranged from  pound2482- pound5222 for MI and from  pound4900- pound6694 for stroke. 
      Costs for the year a non-fatal event occurred ranged from  pound5071- pound29,249 for MI 
      and from  pound5171- pound38,732 for stroke. Annual follow-up costs ranged from  pound945- pound1616 
      for an MI and from  pound4704- pound12,926 for a stroke. Economic evaluations from 12 
      countries were identified, and costs of complications showed similar variability 
      to the primary studies. DISCUSSION: The costs identified within primary studies 
      varied between and within countries. Many studies used costs estimated in studies 
      not specific to patients with T2DM. Data gaps included a detailed breakdown of 
      resource use, which affected the ability to compare data across countries. 
      CONCLUSIONS: In the development of economic models for patients with T2DM, the 
      use of accurate estimates of costs associated with MI and stroke is important. 
      When country-specific costs are not available, clear justification for the choice 
      of estimates should be provided.
FAU - Brennan, Victoria K
AU  - Brennan VK
AD  - RTI Health Solutions , Ann Arbor, MI , USA.
FAU - Colosia, Ann D
AU  - Colosia AD
FAU - Copley-Merriman, Catherine
AU  - Copley-Merriman C
FAU - Mauskopf, Josephine
AU  - Mauskopf J
FAU - Hass, Bastian
AU  - Hass B
FAU - Palencia, Roberto
AU  - Palencia R
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PT  - Systematic Review
DEP - 20140502
PL  - England
TA  - J Med Econ
JT  - Journal of medical economics
JID - 9892255
SB  - IM
MH  - Comorbidity
MH  - Costs and Cost Analysis
MH  - Cross-Cultural Comparison
MH  - Databases, Bibliographic
MH  - Diabetes Mellitus, Type 2/*economics/epidemiology
MH  - Humans
MH  - Models, Economic
MH  - Myocardial Infarction/*economics/epidemiology
MH  - Stroke/*economics/epidemiology
OTO - NOTNLM
OT  - Cost
OT  - Economic evaluation
OT  - Myocardial infarction
OT  - Stroke
OT  - Type 2 diabetes mellitus
EDAT- 2014/04/30 06:00
MHDA- 2015/02/24 06:00
CRDT- 2014/04/30 06:00
PHST- 2014/04/30 06:00 [entrez]
PHST- 2014/04/30 06:00 [pubmed]
PHST- 2015/02/24 06:00 [medline]
AID - 10.3111/13696998.2014.915847 [doi]
PST - ppublish
SO  - J Med Econ. 2014 Jul;17(7):469-80. doi: 10.3111/13696998.2014.915847. Epub 2014 
      May 2.