PMID- 24780180
OWN - NLM
STAT- MEDLINE
DCOM- 20151105
LR  - 20211021
IS  - 1873-6513 (Electronic)
IS  - 0885-3924 (Print)
IS  - 0885-3924 (Linking)
VI  - 48
IP  - 6
DP  - 2014 Dec
TI  - Mindfulness-oriented recovery enhancement ameliorates the impact of pain on 
      self-reported psychological and physical function among opioid-using chronic pain 
      patients.
PG  - 1091-9
LID - S0885-3924(14)00219-X [pii]
LID - 10.1016/j.jpainsymman.2014.03.006 [doi]
AB  - CONTEXT: Chronic pain impacts one-third of the U.S. population, and its effects 
      are debilitating for individuals and costly to the medical system. Although 
      opioids are commonly prescribed to address chronic pain, they confer risk for 
      misuse and addiction in some patients and may not fully restore life 
      function-particularly with regard to psychosocial factors. Because of the 
      multiplicity of impacts that chronic pain may have on daily functioning, 
      broad-spectrum behavioral interventions are needed. OBJECTIVES: The purpose of 
      this study was to conduct follow-up analyses from a pilot randomized controlled 
      trial of Mindfulness-Oriented Recovery Enhancement (MORE) to assess specific 
      effects of MORE on various biopsychosocial aspects of pain-related impairment. 
      METHODS: Chronic pain patients (N = 115; mean age, 48 +/- 14 years; 68% female) 
      were randomly assigned to either eight weeks of MORE or a support group. Domains 
      of pain-related functional interference were measured with the Brief Pain 
      Inventory at pre- and post-treatment and at a three-month follow-up. Treatment 
      effects were analyzed with multivariate intention-to-treat models. RESULTS: MORE 
      participants reported significantly greater reductions in functional interference 
      than support group participants at post-treatment across all domains, including 
      general activity, mood, walking ability, normal work, relationships, sleep, and 
      enjoyment of life. These effects were largely maintained by the three-month 
      follow-up; however, general activity level and walking ability were no longer 
      significant, indicating differential long-term effects between physiological and 
      psychological functioning. CONCLUSION: Findings demonstrate preliminary efficacy 
      of MORE as a treatment for pain-related functional impairments and suggest that 
      effects may be more pronounced and durable for aspects of psychological function.
CI  - Copyright (c) 2014 American Academy of Hospice and Palliative Medicine. Published 
      by Elsevier Inc. All rights reserved.
FAU - Garland, Eric L
AU  - Garland EL
AD  - Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA; College 
      of Social Work, University of Utah, Salt Lake City, Utah, USA. Electronic 
      address: elgarlan@gmail.com.
FAU - Thomas, Elizabeth
AU  - Thomas E
AD  - College of Social Work, University of Utah, Salt Lake City, Utah, USA.
FAU - Howard, Matthew O
AU  - Howard MO
AD  - School of Social Work, University of North Carolina, Chapel Hill, North Carolina, 
      USA.
LA  - eng
GR  - R03 DA032517/DA/NIDA NIH HHS/United States
GR  - R34 DA037005/DA/NIDA NIH HHS/United States
GR  - DA037005/DA/NIDA NIH HHS/United States
GR  - DA032517/DA/NIDA NIH HHS/United States
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, N.I.H., Extramural
DEP - 20140426
PL  - United States
TA  - J Pain Symptom Manage
JT  - Journal of pain and symptom management
JID - 8605836
RN  - 0 (Analgesics, Opioid)
SB  - IM
MH  - Analgesics, Opioid/*therapeutic use
MH  - Chronic Pain/physiopathology/*psychology/*therapy
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Mindfulness/*methods
MH  - Multivariate Analysis
MH  - Pain Measurement
MH  - Pilot Projects
MH  - Quality of Life
MH  - Self Report
MH  - Treatment Outcome
PMC - PMC4209314
MID - NIHMS589996
OTO - NOTNLM
OT  - Mindfulness
OT  - chronic pain
OT  - function
OT  - impairment
OT  - opioid
OT  - quality of life
EDAT- 2014/05/02 06:00
MHDA- 2015/11/06 06:00
PMCR- 2015/12/01
CRDT- 2014/05/01 06:00
PHST- 2013/11/21 00:00 [received]
PHST- 2014/03/03 00:00 [revised]
PHST- 2014/04/02 00:00 [accepted]
PHST- 2014/05/01 06:00 [entrez]
PHST- 2014/05/02 06:00 [pubmed]
PHST- 2015/11/06 06:00 [medline]
PHST- 2015/12/01 00:00 [pmc-release]
AID - S0885-3924(14)00219-X [pii]
AID - 10.1016/j.jpainsymman.2014.03.006 [doi]
PST - ppublish
SO  - J Pain Symptom Manage. 2014 Dec;48(6):1091-9. doi: 
      10.1016/j.jpainsymman.2014.03.006. Epub 2014 Apr 26.