PMID- 24780351
OWN - NLM
STAT- MEDLINE
DCOM- 20151123
LR  - 20161125
IS  - 1878-4119 (Electronic)
IS  - 1010-5182 (Linking)
VI  - 42
IP  - 7
DP  - 2014 Oct
TI  - Stability study of total temporomandibular joint replacement on sheep.
PG  - 1265-70
LID - S1010-5182(14)00088-2 [pii]
LID - 10.1016/j.jcms.2014.03.008 [doi]
AB  - OBJECTIVE: To evaluate the stability of our custom-made prosthesis by 
      establishing the model of sheep total temporomandibular joint (TMJ) replacement. 
      METHODS: Six sheep were included in our study. Spiral computed tomography (CT) 
      data of all sheep was obtained and transformed into 3-dimensional model by 
      surgicase5.0 software preoperatively. Total TMJ prostheses were made based on the 
      skull model. Ultra-high molecular weight polyethylene was used to make glenoid 
      fossa lining, while titanium alloy to prefabricate mandibular retention handle 
      and titanium plate over glenoid fossa. Cobalt-chromium-molybdenum alloy was also 
      used to prefabricate the condyle. The right sides of all sheep, as the 
      experimental group, were carried out total TMJ replacement, while the left sides 
      were as the control group. The bone in both experimental and control side were 
      excised after 3 and 6 months. Scanning electron microscope (SEM) was used to 
      observe the interface between bone and prosthesis. Van Gieson staining and 
      immunohistochemical staining (IHC) were used respectively to observe the 
      interface of titanium screw and bone and the expression of alkaline phosphatase 
      (ALP). RESULTS: SEM and Van Gieson staining showed that there was immature bone 
      and osteoid formed in the interface of prosthesis and bone after 3 months. While 
      after 6 months, there was osseointegration between them. IHC showed that the 
      expression of ALP in the experimental side was much higher than in the control 
      side after 3 months and its expression decreased after 6 months with no 
      difference from the control side. CONCLUSION: The custom-made TMJ prosthesis 
      which was designed and manufactured by ourselves has good stability after total 
      TMJ replacement.
CI  - Copyright (c) 2014 European Association for Cranio-Maxillo-Facial Surgery. 
      Published by Elsevier Ltd. All rights reserved.
FAU - Shen, Pei
AU  - Shen P
AD  - Department of Oral Surgery, Ninth People's Hospital, College of Stomatology, 
      Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of 
      Stomatology & Shanghai Research Institute of Stomatology, No. 639, ZhiZaoJu Rd, 
      200011 Shanghai, People's Republic of China.
FAU - Zhang, Shan Yong
AU  - Zhang SY
AD  - Department of Oral Surgery, Ninth People's Hospital, College of Stomatology, 
      Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of 
      Stomatology & Shanghai Research Institute of Stomatology, No. 639, ZhiZaoJu Rd, 
      200011 Shanghai, People's Republic of China. Electronic address: 
      zhangshanyong@126.com.
FAU - Yang, Chi
AU  - Yang C
AD  - Department of Oral Surgery, Ninth People's Hospital, College of Stomatology, 
      Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of 
      Stomatology & Shanghai Research Institute of Stomatology, No. 639, ZhiZaoJu Rd, 
      200011 Shanghai, People's Republic of China.
FAU - Yun, Bai
AU  - Yun B
AD  - Department of Oral Surgery, Ninth People's Hospital, College of Stomatology, 
      Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of 
      Stomatology & Shanghai Research Institute of Stomatology, No. 639, ZhiZaoJu Rd, 
      200011 Shanghai, People's Republic of China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140402
PL  - Scotland
TA  - J Craniomaxillofac Surg
JT  - Journal of cranio-maxillo-facial surgery : official publication of the European 
      Association for Cranio-Maxillo-Facial Surgery
JID - 8704309
RN  - 0 (Alloys)
RN  - 0 (Biocompatible Materials)
RN  - 0 (Coloring Agents)
RN  - 0 (Polyethylenes)
RN  - 0 (ultra-high molecular weight polyethylene)
RN  - 12629-02-6 (Vitallium)
RN  - D1JT611TNE (Titanium)
RN  - EC 3.1.3.1 (Alkaline Phosphatase)
SB  - IM
MH  - Alkaline Phosphatase/analysis
MH  - Alloys/chemistry
MH  - Animals
MH  - Arthroplasty, Replacement/*methods
MH  - Biocompatible Materials/chemistry
MH  - Bone Matrix/pathology
MH  - Bone-Implant Interface/pathology
MH  - Coloring Agents
MH  - Computer Simulation
MH  - Imaging, Three-Dimensional/methods
MH  - *Joint Prosthesis
MH  - Mandible/pathology
MH  - Microscopy, Electron, Scanning
MH  - Models, Animal
MH  - Osseointegration/physiology
MH  - Osteogenesis/physiology
MH  - Polyethylenes/chemistry
MH  - *Prosthesis Design
MH  - Sheep
MH  - Temporal Bone/pathology
MH  - Temporomandibular Joint/diagnostic imaging/pathology/*surgery
MH  - Titanium/chemistry
MH  - Tomography, Spiral Computed/methods
MH  - User-Computer Interface
MH  - Vitallium/chemistry
OTO - NOTNLM
OT  - Osseointegration
OT  - Sheep
OT  - Stability
OT  - Total temporomandibular joint replacement
EDAT- 2014/05/02 06:00
MHDA- 2015/12/15 06:00
CRDT- 2014/05/01 06:00
PHST- 2013/07/25 00:00 [received]
PHST- 2014/01/11 00:00 [revised]
PHST- 2014/03/10 00:00 [accepted]
PHST- 2014/05/01 06:00 [entrez]
PHST- 2014/05/02 06:00 [pubmed]
PHST- 2015/12/15 06:00 [medline]
AID - S1010-5182(14)00088-2 [pii]
AID - 10.1016/j.jcms.2014.03.008 [doi]
PST - ppublish
SO  - J Craniomaxillofac Surg. 2014 Oct;42(7):1265-70. doi: 10.1016/j.jcms.2014.03.008. 
      Epub 2014 Apr 2.