PMID- 24781821
OWN - NLM
STAT- MEDLINE
DCOM- 20161109
LR  - 20220408
VI  - 124
IP  - 6
DP  - 2014
TI  - Nutritional habits and oxidative stress in postmenopausal age.
PG  - 298-305
LID - AOP_14_036 [pii]
AB  - INTRODUCTION:  Postmenopausal obesity increases the risk of oxidative stress, but 
      such an association in newly diagnosed dyslipidemia after menopause requires 
      detailed research. OBJECTIVES:  The aim of the study was to evaluate the 
      relations between oxidative processes, newly diagnosed dyslipidemia, and 
      nutritional behavior in postmenopausal women who did not receive hypolipidemic 
      treatment. PATIENTS AND METHODS:  The nutritional status, dietary habits, and 
      oxidative stress parameters were evaluated in 102 postmenopausal women (51 obese 
      and 51 normal‑weight subjects) without lipid disturbances before menopause. 
      RESULTS:  In obese subjects, hypercholesterolemia, higher levels of 
      malondialdehyde and advanced oxidation protein products (AOPPs), and a positive 
      correlation between AOPPs and low‑density lipoprotein cholesterol (LDL-C) were 
      observed. Plasma superoxide dismutase (SOD) activity positively correlated with 
      high‑density lipoprotein cholesterol (HDL-C) and negatively with the ratios of 
      total cholesterol to HDL-C and LDL-C to HDL-C in both groups. In obese women, 
      daily food rations were characterized by a higher intake of copper and of energy 
      from fat and saturated fatty acids (SFA), while the intake of carbohydrates and 
      selenium was lower than that in lean women (P <0.05). The multivariable models 
      showed a significant effect of SFA and selenium intake on the variability of 
      serum SOD activity (P = 0.003; R2adj = 17%) and malondialdehyde concentrations (P 
      = 0.00001; R2adj = 45%) in obese women. CONCLUSIONS:  The study showed that 
      oxidative stress processes are present at early stages of hypercholesterolemia in 
      obese postmenopausal women and may be caused by a poorly balanced diet.
FAU - Grygiel-Gorniak, Bogna
AU  - Grygiel-Gorniak B
FAU - Marcinkowska, Justyna
AU  - Marcinkowska J
FAU - Szczepanik, Adam
AU  - Szczepanik A
FAU - Przyslawski, Juliusz
AU  - Przyslawski J
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140429
PL  - Poland
TA  - Pol Arch Med Wewn
JT  - Polskie Archiwum Medycyny Wewnetrznej
JID - 0401225
SB  - IM
MH  - Dyslipidemias/*physiopathology
MH  - Feeding Behavior/*physiology
MH  - Female
MH  - Humans
MH  - Hypercholesterolemia/*physiopathology
MH  - Middle Aged
MH  - Nutritional Status/*physiology
MH  - Obesity/*physiopathology
MH  - Oxidative Stress/*physiology
MH  - Postmenopause/*physiology/*psychology
EDAT- 2014/05/02 06:00
MHDA- 2016/11/10 06:00
CRDT- 2014/05/01 06:00
PHST- 2014/05/01 06:00 [entrez]
PHST- 2014/05/02 06:00 [pubmed]
PHST- 2016/11/10 06:00 [medline]
AID - AOP_14_036 [pii]
AID - 10.20452/pamw.2293 [doi]
PST - ppublish
SO  - Pol Arch Med Wewn. 2014;124(6):298-305. doi: 10.20452/pamw.2293. Epub 2014 Apr 
      29.