PMID- 24785495 OWN - NLM STAT- MEDLINE DCOM- 20141217 LR - 20160518 IS - 1939-3229 (Electronic) IS - 1939-3210 (Linking) VI - 3 IP - 2 DP - 2010 TI - Assessing quality of raw milk in southern Greece in the aspect of certain benzimidazole residues. PG - 73-9 LID - 10.1080/19440049.2010.487877 [doi] AB - Benzimidazoles are veterinary drugs widely used against endoparasites in food-producing animals. Albendazole (ABZ), a benzimidazole, is believed to cause embryotoxicity, teratogenicity and other adverse health effects. This study assessed the residue levels of ABZ and its two major metabolites, the sulfoxide (ABZ-SO) and sulfone (ABZ-SO2), in raw milk samples collected from farms in southern Greece during the spring and autumn of 2008. Analysis was performed by HPLC using a diode array detector. A total of 16% of the 89 samples examined were positive for ABZ metabolites in the range 11-70 ng ml(-1), but the parent compound was not detected in any sample. A geographical variation in positive samples was observed, but season or milk type (ovine, bovine, goat) was unrelated to the presence of residues. Considering the lipophilic character of these substances and the possibility of higher concentrations in dairy foods, we suggest greater controlled usage of these drugs. FAU - Tsiboukis, Dimitrios AU - Tsiboukis D AD - a Laboratory of Public Health, Medical School, University of Patras , Patras GR-26 504 , Greece. FAU - Sazakli, Eleni AU - Sazakli E FAU - Gortzi, Olga AU - Gortzi O FAU - Hadjichristodoulou, Christos AU - Hadjichristodoulou C FAU - Matara, Chrisanthi AU - Matara C FAU - Leotsinidis, Michalis AU - Leotsinidis M LA - eng PT - Journal Article PL - England TA - Food Addit Contam Part B Surveill JT - Food additives & contaminants. Part B, Surveillance JID - 101317183 RN - 0 (Anthelmintics) RN - 0 (Sulfones) RN - 0 (Sulfoxides) RN - F4216019LN (Albendazole) SB - IM MH - Albendazole/analogs & derivatives/*analysis MH - Animals MH - Anthelmintics/*analysis MH - Cattle MH - Chromatography, High Pressure Liquid MH - *Diet MH - Environmental Exposure/*analysis MH - Food Contamination/*analysis MH - Goats MH - Greece MH - Humans MH - Milk/*chemistry MH - Seasons MH - Sheep MH - Sulfones/analysis MH - Sulfoxides/analysis OTO - NOTNLM OT - albendazole OT - anthelmintics OT - milk OT - veterinary drugs EDAT- 2010/06/01 00:00 MHDA- 2014/12/18 06:00 CRDT- 2014/05/03 06:00 PHST- 2014/05/03 06:00 [entrez] PHST- 2010/06/01 00:00 [pubmed] PHST- 2014/12/18 06:00 [medline] AID - 10.1080/19440049.2010.487877 [doi] PST - ppublish SO - Food Addit Contam Part B Surveill. 2010;3(2):73-9. doi: 10.1080/19440049.2010.487877.