PMID- 24788068
OWN - NLM
STAT- MEDLINE
DCOM- 20141218
LR  - 20220311
IS  - 1932-6203 (Electronic)
IS  - 1932-6203 (Linking)
VI  - 9
IP  - 5
DP  - 2014
TI  - Are the 10 meter and 6 minute walk tests redundant in patients with spinal cord 
      injury?
PG  - e94108
LID - 10.1371/journal.pone.0094108 [doi]
LID - e94108
AB  - OBJECTIVE: To evaluate the relationship and redundancy between gait speeds 
      measured by the 10 Meter Walk Test (10MWT) and 6 Minute Walk Test (6MWT) after 
      motor incomplete spinal cord injury (iSCI). To identify gait speed thresholds 
      supporting functional ambulation as measured with the Spinal Cord Injury 
      Functional Ambulation Inventory (SCI-FAI). DESIGN: Prospective observational 
      cohort. SETTING: Seven outpatient rehabilitation centers from the Christopher and 
      Dana Reeve Foundation NeuroRecovery Network (NRN). PARTICIPANTS: 249 NRN patients 
      with American Spinal Injury Association Impairment Scale (AIS) level C (n = 20), 
      D (n = 179) and (n = 50) iSCI not AIS evaluated, from February 2008 through April 
      2011. INTERVENTIONS: Locomotor training using body weight support and walking on 
      a treadmill, overground and home/community practice. MAIN OUTCOME MEASURE(S): 
      10MWT and 6MWT collected at enrollment, approximately every 20 sessions, and upon 
      discharge. RESULTS: The 10MWT and 6MWT speeds were highly correlated and the 
      10MWT speeds were generally faster. However, the predicted 6MWT gait speed from 
      the 10MWT, revealed increasing error with increased gait speed. Regression lines 
      remained significantly different from lines of agreement, when the group was 
      divided into fast (>/=0.44 m/s) and slow walkers (<0.44 m/s). Significant 
      differences between 6MWT and 10MWT gait speeds were observed across SCI-FAI 
      walking mobility categories (Wilcoxon sign rank test p<.001), and mean speed 
      thresholds for limited community ambulation differed for each measure. The 
      smallest real difference for the 6MWT and 10MWT, as well as the minimally 
      clinically important difference (MCID) values, were also distinct for the two 
      tests. CONCLUSIONS: While the speeds were correlated between the 6MWT and 10MWT, 
      redundancy in the tests using predictive modeling was not observed. Different 
      speed thresholds and separate MCIDs were defined for community ambulation for 
      each test.
FAU - Forrest, Gail F
AU  - Forrest GF
AD  - Human Performance and Engineering Laboratory, Kessler Foundation Research Center, 
      West Orange, New Jersey, United States of America; Department of Physical 
      Medicine and Rehabilitation, Rutgers, New Jersey Medical School, Newark, New 
      Jersey, United States of America.
FAU - Hutchinson, Karen
AU  - Hutchinson K
AD  - Department of Physical Therapy and Athletic Training, Boston University, Boston, 
      Massachusetts, United States of America.
FAU - Lorenz, Douglas J
AU  - Lorenz DJ
AD  - Department of Bioinformatics and Biostatistics, School of Public Health and 
      Information Sciences, University of Louisville, Louisville, Kentucky, United 
      States of America; Kentucky Spinal Cord Research Center, University of 
      Louisville, Louisville, Kentucky, United States of America.
FAU - Buehner, Jeffrey J
AU  - Buehner JJ
AD  - Wexner Medical Center at the Ohio State University- Dodd Hall, Columbus, Ohio, 
      United States of America.
FAU - Vanhiel, Leslie R
AU  - Vanhiel LR
AD  - Hulse Spinal Cord Injury Lab and Crawford Research Institute, Shepherd Center, 
      Atlanta, Georgia, United States of America.
FAU - Sisto, Sue Ann
AU  - Sisto SA
AD  - State University of New York at Stony Brook, School of Health Technology and 
      Management, Research and Development Park, Rehabilitation Research and Movement 
      Performance Laboratory, Stony Brook, New York, United States of America.
FAU - Basso, D Michele
AU  - Basso DM
AD  - The Ohio State University, School of Allied Medical Professions, Center for Brain 
      and Spinal Cord Repair, Columbus, Ohio, United States of America.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140501
PL  - United States
TA  - PLoS One
JT  - PloS one
JID - 101285081
SB  - IM
MH  - Adult
MH  - *Exercise Therapy
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Spinal Cord Injuries/*rehabilitation
MH  - Treatment Outcome
MH  - *Walking
PMC - PMC4006773
COIS- Competing Interests: The authors have declared that no competing interests exist.
EDAT- 2014/05/03 06:00
MHDA- 2014/12/19 06:00
PMCR- 2014/05/01
CRDT- 2014/05/03 06:00
PHST- 2013/07/25 00:00 [received]
PHST- 2014/03/12 00:00 [accepted]
PHST- 2014/05/03 06:00 [entrez]
PHST- 2014/05/03 06:00 [pubmed]
PHST- 2014/12/19 06:00 [medline]
PHST- 2014/05/01 00:00 [pmc-release]
AID - PONE-D-13-30731 [pii]
AID - 10.1371/journal.pone.0094108 [doi]
PST - epublish
SO  - PLoS One. 2014 May 1;9(5):e94108. doi: 10.1371/journal.pone.0094108. eCollection 
      2014.